6WK7
 
 | | Crystal Structure Analysis of a poly(thymine) DNA duplex | | 分子名称: | 1,3,5-triazine-2,4,6-triamine, DNA (5'-D(*TP*TP*TP*TP*TP*T)-3') | | 著者 | Li, Q, Zhao, J, Liu, L, Mandal, S, Rizzuto, F.J, He, H, Wei, S, Jonchhe, S, Sleiman, H.F, Mao, H, Mao, C. | | 登録日 | 2020-04-15 | | 公開日 | 2020-07-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.423 Å) | | 主引用文献 | A poly(thymine)-melamine duplex for the assembly of DNA nanomaterials.
Nat Mater, 19, 2020
|
|
5E89
 | | Crystal structure of Human galectin-3 CRD in complex with 3-fluophenyl-1,2,3-triazolyl thiodigalactoside inhibitor | | 分子名称: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, CHLORIDE ION, Galectin-3 | | 著者 | Collins, P.M, Blanchard, H. | | 登録日 | 2015-10-13 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition.
Chembiochem, 17, 2016
|
|
5E8A
 | | Crystal structure of Human galectin-3 CRD in complex with 4-fluophenyl-1,2,3-triazolyl thiodigalactoside inhibitor | | 分子名称: | 3-deoxy-3-[4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, CHLORIDE ION, Galectin-3 | | 著者 | Collins, P.M, Blanchard, H. | | 登録日 | 2015-10-13 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition.
Chembiochem, 17, 2016
|
|
6DVD
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) with 6 nt spacer and bromine labelled in position "-11 | | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*A)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2018-06-23 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.899 Å) | | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
|
|
6DVB
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer | | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2018-06-23 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
|
|
6DVE
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF selenomethionine-labelled sigma factor L) with 6 nt spacer | | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*GP*AP*GP*TP*AP*AP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2018-06-23 | | 公開日 | 2019-02-20 | | 最終更新日 | 2019-02-27 | | 実験手法 | X-RAY DIFFRACTION (3.812 Å) | | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
|
|
6DV9
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer | | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2018-06-23 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
|
|
5UHF
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-IX336 | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.345 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UHG
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-AAP1 and Rifampin | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.971 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UH6
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2ntRNA in complex with Rifampin | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.837 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UH8
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.176 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UH9
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.402 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UHE
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-AAP1 | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4.039 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UH5
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-10 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.746 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UH7
 | |
5UHD
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA in complex with Rifampin | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4.01 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UHC
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.796 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UHA
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.906 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
5UHB
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with Rifampin | | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2017-01-11 | | 公開日 | 2017-04-12 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.29 Å) | | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66, 2017
|
|
6ASG
 | | Crystal structure of Thermus thermophilus RNA polymerase core enzyme | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Liu, Y, Lin, W, Ying, R, Ebright, R.H. | | 登録日 | 2017-08-24 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).
Mol. Cell, 70, 2018
|
|
6FBV
 | | Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Das, K, Lin, W, Ebright, E. | | 登録日 | 2017-12-19 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).
Mol. Cell, 70, 2018
|
|
6DVC
 | | Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer | | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | | 登録日 | 2018-06-23 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
|
|
6TF7
 | | Human galectin-3c in complex with a galactose derivative | | 分子名称: | 4-fluoranyl-~{N}-[[(2~{S},3~{R},4~{R},5~{R},6~{R})-6-(hydroxymethyl)-3,5-bis(oxidanyl)-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxan-2-yl]methyl]naphthalene-1-carboxamide, CHLORIDE ION, Galectin-3, ... | | 著者 | Nilsson, U.J, Zetterberg, F, Hakansson, M, Logan, D.T. | | 登録日 | 2019-11-13 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | 3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-sites for High-Affinity and High-Selectivity Inhibition of Galectin-3.
Molecules, 24, 2019
|
|
6TF6
 | | Human galectin-3c in complex with a galactose derivative | | 分子名称: | CHLORIDE ION, Galectin-3, ~{N}-[[(2~{S},3~{S},4~{R},5~{S},6~{R})-4-[[5,6-bis(fluoranyl)-2-oxidanylidene-chromen-3-yl]methoxy]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]methyl]-4-fluoranyl-naphthalene-1-carboxamide | | 著者 | Nilsson, U.J, Zetterberg, F, Hakansson, M, Logan, D.T. | | 登録日 | 2019-11-13 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | 3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-sites for High-Affinity and High-Selectivity Inhibition of Galectin-3.
Molecules, 24, 2019
|
|
1MFA
 | |
