Crystal structure of Mycobacterium tuberculosis transcription initiation complex

Summary for 5UHA

Related5UH6 5UH7 5UH8 5UH9 5UHB 5UHC 5UHD 5UHE 5UHF 5UHG
DescriptorDNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (9 entities in total)
Functional Keywordsrna polymerase complex, transcription, dna, rna, transcription-dna complex, transcription/dna
Biological sourceMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Cellular locationCytoplasm  P9WGI1
Total number of polymer chains8
Total molecular weight434461.71
Lin, W.,Das, K.,Feng, Y.,Ebright, R.H. (deposition date: 2017-01-11, release date: 2017-04-12, Last modification date: 2017-11-22)
Primary citation
Lin, W.,Mandal, S.,Degen, D.,Liu, Y.,Ebright, Y.W.,Li, S.,Feng, Y.,Zhang, Y.,Mandal, S.,Jiang, Y.,Liu, S.,Gigliotti, M.,Talaue, M.,Connell, N.,Das, K.,Arnold, E.,Ebright, R.H.
Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Mol. Cell, 66:169-179.e8, 2017
PubMed: 28392175 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2017.03.001
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27780.7%2.0%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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