4PV6
 
 | | Crystal Structure Analysis of Ard1 from Thermoplasma volcanium | | 分子名称: | ACETYL COENZYME *A, COENZYME A, N-terminal acetyltransferase complex subunit [ARD1] | | 著者 | Ma, C, Lee, S.J, Lee, B.J. | | 登録日 | 2014-03-15 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | Structure of Thermoplasma volcanium Ard1 belongs to N-acetyltransferase family member suggesting multiple ligand binding modes with acetyl coenzyme A and coenzyme A.
Biochim.Biophys.Acta, 1844, 2014
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5H5U
 | | Mechanistic insights into the alternative translation termination by ArfA and RF2 | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Ma, C, Kurita, D, Li, N, Chen, Y, Himeno, H, Gao, N. | | 登録日 | 2016-11-09 | | 公開日 | 2017-01-25 | | 最終更新日 | 2018-10-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanistic insights into the alternative translation termination by ArfA and RF2
Nature, 541, 2017
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6K6U
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4Z9E
 | | Alba from Thermoplasma volcanium | | 分子名称: | DNA/RNA-binding protein Alba | | 著者 | Ma, C, Lee, S.J, Pathak, C, Lee, B.J. | | 登録日 | 2015-04-10 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Alba from Thermoplasma volcanium belongs to alpha-NAT's: An insight into the structural aspects of Tv Alba and its acetylation by Tv Ard1.
Arch.Biochem.Biophys., 590, 2016
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5H4P
 | | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1 | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Ma, C, Wu, S, Li, N, Chen, Y, Yan, K, Li, Z, Zheng, L, Lei, J, Woolford, J.L, Gao, N. | | 登録日 | 2016-11-01 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
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4PQP
 | | Crystal structure of human SNX14 PX domain in space group P43212 | | 分子名称: | GLYCEROL, Sorting nexin-14 | | 著者 | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | | 登録日 | 2014-03-03 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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4PQO
 | | Structure of the human SNX14 PX domain in space group I41 | | 分子名称: | Sorting nexin-14 | | 著者 | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | | 登録日 | 2014-03-03 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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2L2I
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6WTT
 | | Crystals Structure of the SARS-CoV-2 (COVID-19) main protease with inhibitor GC-376 | | 分子名称: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ... | | 著者 | Sacco, M, Ma, C, Chen, Y, Wang, J. | | 登録日 | 2020-05-03 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
Cell Res., 30, 2020
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2KI2
 | | Solution Structure of ss-DNA Binding Protein 12RNP2 Precursor, HP0827(O25501_HELPY) form Helicobacter pylori | | 分子名称: | Ss-DNA binding protein 12RNP2 | | 著者 | Ma, C, Lee, J, Kim, J, Park, S, Kwon, A, Lee, B. | | 登録日 | 2009-04-20 | | 公開日 | 2009-10-20 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of HP0827 (O25501_HELPY) from Helicobacter pylori: model of the possible RNA-binding site
J.Biochem., 146, 2009
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7JRN
 | | Crystal structure of the wild type SARS-CoV-2 papain-like protease (PLPro) with inhibitor GRL0617 | | 分子名称: | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, SULFATE ION, ... | | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | | 登録日 | 2020-08-12 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay.
Acs Cent.Sci., 7, 2021
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6K61
 | | Cryo-EM structure of the tetrameric photosystem I from a heterocyst-forming cyanobacterium Anabaena sp. PCC7120 | | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | 著者 | Zheng, L, Li, Y, Li, X, Zhong, Q, Li, N, Zhang, K, Zhang, Y, Chu, H, Ma, C, Li, G, Zhao, J, Gao, N. | | 登録日 | 2019-05-31 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.37 Å) | | 主引用文献 | Structural and functional insights into the tetrameric photosystem I from heterocyst-forming cyanobacteria.
Nat.Plants, 5, 2019
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2OAZ
 | | Human Methionine Aminopeptidase-2 Complexed with SB-587094 | | 分子名称: | COBALT (II) ION, N-(2-ISOPROPYLPHENYL)-3-[(2-THIENYLMETHYL)THIO]-1H-1,2,4-TRIAZOL-5-AMINE, human Methionine Amino Peptidase 2 | | 著者 | Marino Jr, J.P, Fisher, P.W, Hofmann, G.A, Kirkpatrick, R, Janson, C.A, Johnson, R.K, Ma, C, Mattern, M, Meek, T.D, Ryan, D, Schulz, C, Smith, W.W, Tew, D.G, Tomazek Jr, T.A, Veber, D.F, Xiong, W.C, Yamamoto, Y, Yamashita, K, Yang, G, Thompson, S.K. | | 登録日 | 2006-12-18 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore.
J.Med.Chem., 50, 2007
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6LU8
 | | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | | 登録日 | 2020-01-26 | | 公開日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
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6LQM
 | | Cryo-EM structure of a pre-60S ribosomal subunit - state C | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | | 登録日 | 2020-01-14 | | 公開日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
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6LSR
 | | Cryo-EM structure of a pre-60S ribosomal subunit - state B | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | | 登録日 | 2020-01-20 | | 公開日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
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6LSS
 | | Cryo-EM structure of a pre-60S ribosomal subunit - state preA | | 分子名称: | 28S rRNA, 5S rRNA, 60S ribosomal protein L11, ... | | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | | 登録日 | 2020-01-20 | | 公開日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
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4Y21
 | | Crystal Structure of Munc13-1 MUN domain | | 分子名称: | Protein unc-13 homolog A | | 著者 | Yang, X.Y, Wang, S, Sheng, Y, Zhang, M, Zou, W.J, Wu, L.J, Kang, L.J, Rizo, J, Zhang, R.G, Xu, T, Ma, C. | | 登録日 | 2015-02-09 | | 公開日 | 2015-06-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming.
Nat.Struct.Mol.Biol., 22, 2015
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2XA8
 | | Crystal structure of the Fab domain of omalizumab at 2.41A | | 分子名称: | OMALIZUMAB HEAVY CHAIN, OMALIZUMAB LIGHT CHAIN | | 著者 | Huang, C.H, Hung, F.H.A, Lim, C, Chang, T.W, Ma, C. | | 登録日 | 2010-03-30 | | 公開日 | 2011-05-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structural and Physical Basis for Anti-IgE Therapy.
Sci Rep, 5, 2015
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1ZXO
 | | X-ray Crystal Structure of Protein Q8A1P1 from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR25. | | 分子名称: | conserved hypothetical protein Q8A1P1 | | 著者 | Kuzin, A.P, Yong, W, Forouhar, F, Vorobiev, S, Xiao, R, Ma, C, Acton, T, Montelione, G.T, Hunt, J, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2005-06-08 | | 公開日 | 2005-07-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | X-Ray structure of the hypothetical protein Q8A1P1 at the resolution 3.2A. Northeast Structural Genomics Consortium target BtR25.
To be Published
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3PFT
 | | Crystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN From Mycobacterium goodii | | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavin reductase | | 著者 | Li, Q, Xu, P, Ma, C, Gu, L, Liu, X, Zhang, C, Li, N, Su, J, Li, B, Liu, S. | | 登録日 | 2010-10-29 | | 公開日 | 2011-11-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | The flavin reductase DSZD from a desulfurizing mycobacterium goodii strain: systemic manipulation and investigation based on the crystal structure
To be Published
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2AJA
 | | X-Ray structure of an ankyrin repeat family protein Q5ZSV0 from Legionella pneumophila. Northeast Structural Genomics Consortium target LgR21. | | 分子名称: | ankyrin repeat family protein | | 著者 | Kuzin, A.P, Chen, Y, Acton, T, Xiao, R, Conover, K, Ma, C, Kellie, R, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2005-08-01 | | 公開日 | 2005-08-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | X-Ray structure of an ankyrin repeat family protein Q5ZSV0 from Legionella pneumophila.
To be Published
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3J8G
 | | Electron cryo-microscopy structure of EngA bound with the 50S ribosomal subunit | | 分子名称: | 23S rRNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | | 著者 | Zhang, X, Yan, K, Zhang, Y, Li, N, Ma, C, Li, Z, Zhang, Y, Feng, B, Liu, J, Sun, Y, Xu, Y, Lei, J, Gao, N. | | 登録日 | 2014-10-24 | | 公開日 | 2014-11-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
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3J3W
 | | Atomic model of the immature 50S subunit from Bacillus subtilis (state II-a) | | 分子名称: | 50S ribosomal protein L1, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | 著者 | Li, N, Guo, Q, Zhang, Y, Yuan, Y, Ma, C, Lei, J, Gao, N. | | 登録日 | 2013-04-28 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (10.7 Å) | | 主引用文献 | Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
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3J3V
 | | Atomic model of the immature 50S subunit from Bacillus subtilis (state I-a) | | 分子名称: | 50S ribosomal protein L1, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | 著者 | Li, N, Guo, Q, Zhang, Y, Yuan, Y, Ma, C, Lei, J, Gao, N. | | 登録日 | 2013-04-28 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (13.3 Å) | | 主引用文献 | Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
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