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4XEY
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BU of 4xey by Molmil
Crystal structure of an SH2-kinase domain construct of c-Abl tyrosine kinase
分子名称: N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Tyrosine-protein kinase ABL1
著者Lorenz, S, Deng, P, Kuriyan, J.
登録日2014-12-25
公開日2015-04-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.891 Å)
主引用文献Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity.
Biochem.J., 468, 2015
2VZG
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BU of 2vzg by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha- parvin in complex with paxillin LD2 motif
分子名称: 1,2-ETHANEDIOL, Alpha-parvin, Paxillin, ...
著者Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
登録日2008-08-01
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of the interactions between paxillin LD motifs and alpha-parvin.
Structure, 16, 2008
2VZD
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BU of 2vzd by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha parvin in complex with paxillin LD1 motif
分子名称: 1,2-ETHANEDIOL, ALPHA-PARVIN, GLYCEROL, ...
著者Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
登録日2008-07-31
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin
Structure, 16, 2008
2VZC
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BU of 2vzc by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha parvin
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
登録日2008-07-31
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin
Structure, 16, 2008
2VZI
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BU of 2vzi by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha- parvin in complex with paxillin LD4 motif
分子名称: 1,2-ETHANEDIOL, Alpha-parvin, Paxillin,Paxillin, ...
著者Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
登録日2008-08-01
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural analysis of the interactions between paxillin LD motifs and alpha-parvin.
Structure, 16, 2008
6QH3
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BU of 6qh3 by Molmil
Catalytic domain of the human ubiquitin-conjugating enzyme UBE2S C118M
分子名称: 1,2-ETHANEDIOL, Ubiquitin-conjugating enzyme E2 S
著者Liess, A.K.L, Lorenz, S.
登録日2019-01-15
公開日2019-07-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination.
Structure, 27, 2019
353D
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BU of 353d by Molmil
CRYSTAL STRUCTURE OF DOMAIN A OF THERMUS FLAVUS 5S RRNA AND THE CONTRIBUTION OF WATER MOLECULES TO ITS STRUCTURE
分子名称: RNA (5'-R(*AP*UP*CP*CP*CP*CP*CP*GP*UP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*GP*CP*GP*GP*GP*GP*GP*AP*U)-3')
著者Betzel, C, Lorenz, S, Furste, J.P, Bald, R, Zhang, M, Schneider, T.R, Wilson, K.S, Erdmann, V.A.
登録日1997-09-29
公開日1997-11-10
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of domain A of Thermus flavus 5S rRNA and the contribution of water molecules to its structure.
FEBS Lett., 351, 1994
6QHK
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BU of 6qhk by Molmil
PAO-linked dimer of the catalytic domain of the human ubiquitin-conjugating enzyme UBE2S
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Phenylarsine oxide, ...
著者Liess, A.K.L, Lorenz, S.
登録日2019-01-16
公開日2019-07-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination.
Structure, 27, 2019
8Q0N
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BU of 8q0n by Molmil
HACE1 in complex with RAC1 Q61L
分子名称: E3 ubiquitin-protein ligase HACE1, GUANOSINE-5'-TRIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ...
著者Wolter, M, Duering, J, Dienemann, C, Lorenz, S.
登録日2023-07-28
公開日2024-01-10
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1.
Nat.Struct.Mol.Biol., 31, 2024
8PWL
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BU of 8pwl by Molmil
Cryo-EM structure of a full-length HACE1 dimer
分子名称: E3 ubiquitin-protein ligase HACE1
著者Duering, J, Wolter, M, Dienemann, C, Lorenz, S.
登録日2023-07-20
公開日2024-01-10
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.73 Å)
主引用文献Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1.
Nat.Struct.Mol.Biol., 31, 2024
6XZ1
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BU of 6xz1 by Molmil
Conjugate of the HECT domain of HUWE1 with ubiquitin
分子名称: HECT, UBA and WWE domain containing 1, isoform CRA_a, ...
著者Liu, B, Seenivasan, A, Nair, R, Chen, D, Lowe, E.D, Lorenz, S.
登録日2020-01-31
公開日2021-08-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe.
Acs Chem.Biol., 16, 2021
1JXB
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BU of 1jxb by Molmil
I53A, a point mutant of the cysteine-free variant of E. coli Rnase HI
分子名称: Ribonuclease HI
著者Spudich, G, Lorenz, S, Marqusee, S.
登録日2001-09-06
公開日2002-03-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state.
Protein Sci., 11, 2002
6S98
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BU of 6s98 by Molmil
Crystal structure of the catalytic domain of UBE2S WT.
分子名称: 1,2-ETHANEDIOL, ACETATE ION, SODIUM ION, ...
著者Liess, A.K.L, Lorenz, S.
登録日2019-07-11
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.
Sci.Signal., 13, 2020
6S96
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BU of 6s96 by Molmil
Crystal structure of the catalytic domain of UBE2S C118A.
分子名称: FORMIC ACID, SODIUM ION, Ubiquitin-conjugating enzyme E2 S
著者Liess, A.K.L, Lorenz, S.
登録日2019-07-11
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.
Sci.Signal., 13, 2020
6TGK
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BU of 6tgk by Molmil
Domain swapped E6AP C-lobe dimer
分子名称: ACETATE ION, CALCIUM ION, Ubiquitin-protein ligase E3A
著者Ries, L.K, Feiler, C, Lowe, L.D, Liess, A.K.L, Lorenz, S.
登録日2019-11-16
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of the catalytic C-lobe of the HECT-type ubiquitin ligase E6AP.
Protein Sci., 29, 2020
361D
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BU of 361d by Molmil
CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP
分子名称: RNA (5'-R(*CP*UP*GP*GP*GP*CP*GP*GP*GP*CP*GP*AP*CP*CP*GP*CP*C P*UP*GP*G)-3')
著者Perbandt, M, Nolte, A, Lorenz, S, Erdmann, V.A, Betzel, C.
登録日1997-11-10
公開日1998-07-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of domain E of Thermus flavus 5S rRNA: a helical RNA structure including a hairpin loop.
FEBS Lett., 429, 1998
7AZW
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BU of 7azw by Molmil
Crystal structure of the MIZ1-BTB-domain
分子名称: GLYCEROL, Zinc finger and BTB domain-containing protein 17 isoform X1
著者Orth, B, Sander, B, Diederichs, K, Lorenz, S.
登録日2020-11-17
公開日2021-06-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1.
Structure, 29, 2021
7AZX
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BU of 7azx by Molmil
Crystal structure of the MIZ1-BTB-domain in complex with a HUWE1-derived peptide
分子名称: E3 ubiquitin-protein ligase HUWE1, Zinc finger and BTB domain-containing protein 17 isoform X1
著者Orth, B, Sander, B, Diederichs, K, Lorenz, S.
登録日2020-11-17
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1.
Structure, 29, 2021
7AHF
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BU of 7ahf by Molmil
Dimeric structure of the catalytic domain of the human ubiquitin-conjugating enzyme UBE2S L114E varaiant
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Ubiquitin-conjugating enzyme E2 S
著者Liess, A.K.L, Feiler, C.G, Lorenz, S.
登録日2020-09-24
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural analyses of the ubiquitin-conjugating enzyme UBE2S in different crystal forms
To Be Published
5BNB
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BU of 5bnb by Molmil
Crystal structure of a Ube2S-ubiquitin conjugate
分子名称: Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 S
著者Lorenz, S.G, Feiler, C.G, Kuriyan, J.
登録日2015-05-25
公開日2016-02-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystal Structure of a Ube2S-Ubiquitin Conjugate.
Plos One, 11, 2016
5LP8
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BU of 5lp8 by Molmil
Crystal structure of an asymmetric dimer of the ubiquitin ligase HUWE1
分子名称: E3 ubiquitin-protein ligase HUWE1
著者Sander, B, Lorenz, S.G.
登録日2016-08-12
公開日2017-02-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A conformational switch regulates the ubiquitin ligase HUWE1.
Elife, 6, 2017
8B3G
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BU of 8b3g by Molmil
C(N)RL4CSA-UVSSA-E2-ubiquitin complex.
分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-8, ...
著者Kokic, G, Cramer, P.
登録日2022-09-16
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair.
Nat.Struct.Mol.Biol., 31, 2024
6ELL
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BU of 6ell by Molmil
FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
分子名称: fAB heavy chain, fAB light chain
著者Benz, J, Weigand, S, Dengl, S, Schlothauer, T, Auer, J, Ehler, A, Kettenberger, H, Lorenz, S, Hirschheydt, T, Georges, G.
登録日2017-09-29
公開日2017-11-08
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
To Be Published
6EMJ
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BU of 6emj by Molmil
FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
分子名称: SODIUM ION, fAB heavy chain, fAb light chain
著者Benz, J, Weigand, S, Dengl, S, Schlothauer, T, Auer, J, Ehler, A, Kettenberger, H, Lorenz, S, Hirschheydt, T, Georges, G.
登録日2017-10-02
公開日2017-11-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
To Be Published
6ELJ
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BU of 6elj by Molmil
FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
分子名称: fAB heavy chain, fAB light chain
著者Benz, J, Weigand, S, Dengl, S, Schlothauer, T, Auer, J, Ehler, A, Kettenberger, H, Lorenz, S, Hirschheydt, T, Georges, G.
登録日2017-09-29
公開日2017-11-08
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery
To Be Published

 

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