5LP8
Crystal structure of an asymmetric dimer of the ubiquitin ligase HUWE1
Summary for 5LP8
| Entry DOI | 10.2210/pdb5lp8/pdb |
| Descriptor | E3 ubiquitin-protein ligase HUWE1 (2 entities in total) |
| Functional Keywords | ubiquitin ligase, e3 enzyme, hect, ligase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm : Q7Z6Z7 |
| Total number of polymer chains | 2 |
| Total formula weight | 105903.89 |
| Authors | Sander, B.,Lorenz, S.G. (deposition date: 2016-08-12, release date: 2017-02-22, Last modification date: 2024-01-10) |
| Primary citation | Sander, B.,Xu, W.,Eilers, M.,Popov, N.,Lorenz, S. A conformational switch regulates the ubiquitin ligase HUWE1. Elife, 6:-, 2017 Cited by PubMed: 28193319DOI: 10.7554/eLife.21036 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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