5LP8
Crystal structure of an asymmetric dimer of the ubiquitin ligase HUWE1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | E3 ubiquitin-protein ligase HUWE1 | polymer | 450 | 52951.9 | 2 | UniProt (Q7Z6Z7) Pfam (PF00632) In PDB | Homo sapiens (Human) | ARF-binding protein 1,ARF-BP1,HECT,UBA and WWE domain-containing protein 1,Homologous to E6AP carboxyl terminus homologous protein 9,HectH9,Large structure of UREB1,LASU1,Mcl-1 ubiquitin ligase E3,Mule,Upstream regulatory element-binding protein 1,URE-binding protein 1 |
2 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
B, A: 3951 - 4374 (UniProt: Q7Z6Z7)
PDB | External Database | Details |
---|---|---|
Met 3925 | - | initiating methionine |
Lys 3926 | - | expression tag |
His 3927 | - | expression tag |
His 3928 | - | expression tag |
His 3929 | - | expression tag |
His 3930 | - | expression tag |
His 3931 | - | expression tag |
His 3932 | - | expression tag |
Pro 3933 | - | expression tag |
Met 3934 | - | expression tag |
Ser 3935 | - | expression tag |
Asp 3936 | - | expression tag |
Tyr 3937 | - | expression tag |
Asp 3938 | - | expression tag |
Ile 3939 | - | expression tag |
Pro 3940 | - | expression tag |
Thr 3941 | - | expression tag |
Thr 3942 | - | expression tag |
Glu 3943 | - | expression tag |
Asn 3944 | - | expression tag |
Leu 3945 | - | expression tag |
Tyr 3946 | - | expression tag |
Phe 3947 | - | expression tag |
Gln 3948 | - | expression tag |
Gly 3949 | - | expression tag |
Ala 3950 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 105903.9 | |
All* | Total formula weight | 105903.9 |