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2LI3
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BU of 2li3 by Molmil
Structural and functional analysis of a novel potassium toxin argentinean scorpion Tityus trivittatus reveals a new kappa sub-family
分子名称: Potassium channel toxin kappa-KTX3.1
著者Saucedo-Yanez, A, Del Rio-Portilla, F, Hernandez-Lopez, R.
登録日2011-08-19
公開日2012-01-11
最終更新日2012-04-25
実験手法SOLUTION NMR
主引用文献New Tricks of an Old Pattern: STRUCTURAL VERSATILITY OF SCORPION TOXINS WITH COMMON CYSTEINE SPACING.
J.Biol.Chem., 287, 2012
2BML
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BU of 2bml by Molmil
Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AUTOLYSIN, DEXTROFLOXACINE, ...
著者Fernandez-Tornero, C, Gimenez-Gallego, G, Romero, A, Garcia, E, Pascual-Teresa, B.D, Lopez, R.
登録日2005-03-15
公開日2005-03-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ofloxacin-Like Antibiotics Inhibit Pneumococcal Cell Wall-Degrading Virulence Factors
J.Biol.Chem., 280, 2005
4AIX
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BU of 4aix by Molmil
Crystallographic structure of an amyloidogenic variant, 3rC34Y, of the germinal line lambda 3
分子名称: IG LAMBDA CHAIN V-IV REGION BAU
著者Villalba, M.I, Luna, O.D, Rudino-Pinera, E, Sanchez, R, Sanchez-Lopez, R, Rojas-Trejo, S, Olamendi-Portugal, T, Fernandez-Velasco, D.A, Becerril, B.
登録日2012-02-15
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Site-Directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human Lambda3R Light Chains.
J.Biol.Chem., 290, 2015
4AJ0
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BU of 4aj0 by Molmil
Crystallographic structure of an amyloidogenic variant, 3rCW, of the germinal line lambda 3
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, ACETATE ION, GERMINAL LINE LAMBDA 3 3RCW VARIANT
著者Villalba, M.I, Luna, O.D, Rudino-Pinera, E, Sanchez, R, Sanchez-Lopez, R, Rojas-Trejo, S, Olamendi-Portugal, T, Fernandez-Velasco, D.A, Becerril, B.
登録日2012-02-15
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Site-Directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human Lambda3R Light Chains.
J.Biol.Chem., 290, 2015
4AIZ
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BU of 4aiz by Molmil
Crystallographic structure of 3mJL2 from the germinal line lambda 3
分子名称: 1,5:6,10-dianhydro-3,4,7,8-tetradeoxy-2,9-bis-C-(hydroxymethyl)-L-manno-decitol, CITRIC ACID, SULFATE ION, ...
著者Villalba, M.I, Luna, O.D, Rudino-Pinera, E, Sanchez, R, Sanchez-Lopez, R, Rojas-Trejo, S, Olamendi-Portugal, T, Fernandez-Velasco, D.A, Becerril, B.
登録日2012-02-15
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Site-Directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human Lambda3R Light Chains.
J.Biol.Chem., 290, 2015
1GVM
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BU of 1gvm by Molmil
CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AUTOLYSIN, CHOLINE ION, ...
著者Fernandez-Tornero, C, Lopez, R, Garcia, E, Gimenez-Gallego, G, Romero, A.
登録日2002-02-15
公開日2002-08-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Two New Crystal Forms of the Choline-Binding Domain of the Major Pneumococcal Autolysin: Insights Into the Dynamics of the Active Dimeric
J.Mol.Biol., 321, 2002
3J1T
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BU of 3j1t by Molmil
High affinity dynein microtubule binding domain - tubulin complex
分子名称: Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ...
著者Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E.
登録日2012-06-25
公開日2012-09-26
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structural basis for microtubule binding and release by dynein.
Science, 337, 2012
3J1U
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BU of 3j1u by Molmil
Low affinity dynein microtubule binding domain - tubulin complex
分子名称: Cytoplasmic dynein 1 heavy chain 1, seryl t-RNA synthetase chimera, Tubulin alpha-1B chain, ...
著者Redwine, W.B, Hernandez-Lopez, R, Zou, S, Huang, J, Reck-Peterson, S.L, Leschziner, A.E.
登録日2012-06-25
公開日2012-09-26
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structural basis for microtubule binding and release by dynein.
Science, 337, 2012
7BCB
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BU of 7bcb by Molmil
Crystal structure of the HTH DNA binding protein ArdK from R388 plasmid bound to IR3 DNA
分子名称: DNA (5'-D(*TP*AP*AP*TP*GP*TP*CP*AP*AP*AP*TP*AP*TP*TP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*AP*TP*AP*TP*TP*TP*GP*AP*CP*AP*TP*TP*A)-3'), KORA domain-containing protein
著者Fernandez-Lopez, R, Boer, D.R, Moncalian, G.
登録日2020-12-19
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of direct and inverted DNA sequence repeat recognition by helix-turn-helix transcription factors.
Nucleic Acids Res., 50, 2022
7BCA
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BU of 7bca by Molmil
Crystal structure of the HTH DNA binding protein ArdK from R388 plasmid bound to a direct-repeat DNA element
分子名称: DNA (5'-D(*GP*TP*AP*TP*TP*GP*AP*CP*AP*CP*CP*TP*AP*TP*TP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*AP*TP*AP*GP*GP*TP*GP*TP*CP*AP*AP*TP*AP*C)-3'), KORA domain-containing protein
著者Fernandez-Lopez, R, Boer, D.R, Moncalian, G.
登録日2020-12-18
公開日2022-07-13
最終更新日2022-12-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of direct and inverted DNA sequence repeat recognition by helix-turn-helix transcription factors.
Nucleic Acids Res., 50, 2022
7BBQ
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BU of 7bbq by Molmil
Crystal structure of the HTH DNA binding protein ArdK from R388 plasmid. Apo form.
分子名称: KORA domain-containing protein
著者Fernandez-Lopez, R, Boer, D.R, Moncalian, G.
登録日2020-12-18
公開日2022-07-13
最終更新日2022-12-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of direct and inverted DNA sequence repeat recognition by helix-turn-helix transcription factors.
Nucleic Acids Res., 50, 2022
1H8G
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BU of 1h8g by Molmil
C-terminal domain of the major autolysin (C-LytA) from Streptococcus pneumoniae
分子名称: CHOLINE ION, MAJOR AUTOLYSIN
著者Fernandez-Tornero, C, Garcia, E, Lopez, R, Gimenez-Gallego, G, Romero, A.
登録日2001-02-06
公開日2002-01-31
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Novel Solenoid Fold in the Cell Wall Anchoring Domain of the Pneumococcal Virulence Factor Lyta
Nat.Struct.Biol., 8, 2001
1HCX
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BU of 1hcx by Molmil
Choline binding domain of the major autolysin (C-LytA) from Streptococcus pneumoniae
分子名称: 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride, CHOLINE ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, ...
著者Fernandez-Tornero, C, Lopez, R, Garcia, E, Gimenez-Gallego, G, Romero, A.
登録日2001-05-10
公開日2001-11-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Novel Solenoid Fold in the Cell Wall Anchoring Domain of the Pneumococcal Virulence Factor Lyta
Nat.Struct.Biol., 8, 2001
2KY3
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BU of 2ky3 by Molmil
Solution structure of GS-alfa-Ktx5.4 synthetic scorpion like
分子名称: Potassium channel toxin alpha-KTx 5.4
著者Del Rio-Portilla, F, Ramirez-Cordero, B.E, Brieba-De Castro, L.
登録日2010-05-14
公開日2011-06-01
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Cytotoxicity of recombinant tamapin and related toxin-like peptides on model cell lines.
Chem.Res.Toxicol., 27, 2014
2LO7
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BU of 2lo7 by Molmil
Ts16 NMR solution structure
分子名称: Toxin Ts16
著者del Rio-Portilla, F, Saucedo, A.L, Flores-Solis, D.
登録日2012-01-17
公開日2012-03-14
最終更新日2014-01-15
実験手法SOLUTION NMR
主引用文献New Tricks of an Old Pattern: STRUCTURAL VERSATILITY OF SCORPION TOXINS WITH COMMON CYSTEINE SPACING.
J.Biol.Chem., 287, 2012
2WWD
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BU of 2wwd by Molmil
3D-structure of the modular autolysin LytC from Streptococcus pneumoniae in complex with pneummococcal peptidoglycan fragment
分子名称: 1,4-BETA-N-ACETYLMURAMIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ALANINE, ...
著者Perez-Dorado, I, Sanles, R, Hermoso, J.A, Gonzalez, A, Garcia, A, Garcia, P, Garcia, J.L.
登録日2009-10-22
公開日2010-04-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Insights Into Pneumococcal Fratricide from the Crystal Structures of the Modular Killing Factor Lytc.
Nat.Struct.Mol.Biol., 17, 2010
2WWC
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BU of 2wwc by Molmil
3D-structure of the modular autolysin LytC from Streptococcus pneumoniae in complex with synthetic peptidoglycan ligand
分子名称: 1,4-BETA-N-ACETYLMURAMIDASE, CHOLINE ION, GLYCEROL
著者Perez-Dorado, I, Sanles, R, Hermoso, J.A, Gonzalez, A, Garcia, A, Garcia, P, Garcia, J.L.
登録日2009-10-22
公開日2010-04-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Insights Into Pneumococcal Fratricide from the Crystal Structures of the Modular Killing Factor Lytc.
Nat.Struct.Mol.Biol., 17, 2010
2WW5
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BU of 2ww5 by Molmil
3D-structure of the modular autolysin LytC from Streptococcus pneumoniae at 1.6 A resolution
分子名称: 1,4-BETA-N-ACETYLMURAMIDASE, CHLORIDE ION, CHOLINE ION, ...
著者Perez-Dorado, I, Sanles, R, Hermoso, J.A, Gonzalez, A, Garcia, A, Garcia, P, Garcia, J.L, Menendez, M.
登録日2009-10-21
公開日2010-04-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Insights Into Pneumococcal Fratricide from the Crystal Structures of the Modular Killing Factor Lytc.
Nat.Struct.Mol.Biol., 17, 2010
2K9O
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BU of 2k9o by Molmil
Solution structure of Vm24 synthetic scorpion toxin
分子名称: Vm24 SCORPION toxin
著者del Rio-Portilla, F, Hernandez-Lopez, R, Possani-Postay, L, Gurrola, G.
登録日2008-10-20
公開日2009-11-03
最終更新日2014-05-28
実験手法SOLUTION NMR
主引用文献Structure, function, and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes.
Biochemistry, 51, 2012
2W0K
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BU of 2w0k by Molmil
Crystal structure of the recombinant variable domain 6JAL2
分子名称: V1-22 PROTEIN
著者Rudino-Pinera, E, Gonzalezrubio-Garrido, P, Horjales, E.
登録日2008-08-19
公開日2009-11-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A Single Mutation at the Sheet Switch Region Results in Conformational Changes Favoring Lambda6 Light-Chain Fibrillogenesis.
J.Mol.Biol., 396, 2010
5IR3
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BU of 5ir3 by Molmil
Crystal structure of the recombinant highest fibrillogenic natural mutant (obtained from patient AR) derived from lambda 6 light chain variable domain
分子名称: ACETATE ION, Ig lambda chain V-VI region AR
著者Hernandez-Santoyo, A, Rodriguez-Romero, A.
登録日2016-03-11
公開日2017-06-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Stabilizing an amyloidogenic lambda 6 light chain variable domain.
FEBS J., 284, 2017
5C9K
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BU of 5c9k by Molmil
Crystal structure of a highly fibrillogenic Arg24Gly mutant of the Recombinant variable domain 6AJL2
分子名称: ACETATE ION, Amyloid lambda 6 light chain variable region PIP
著者Hernandez-Santoyo, A, Rodriguez-Romero, A, Luna-Martinez, O.D, Becerril-Lujan, B.
登録日2015-06-27
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Mutating amyloidogenic lambda6 light chain AR back to germline 6aJL2
To Be Published
3BDX
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BU of 3bdx by Molmil
Crystal structure of the unstable and highly fibrillogenic Pro7Ser mutant of the Recombinant variable domain 6AJL2
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Amyloid lambda 6 light chain variable region PIP (fragment), ...
著者Hernandez-Santoyo, A, Fuentes-Silva, D, Del Pozo Yauner, L, Becerril, B, Rodriguez-Romero, A.
登録日2007-11-15
公開日2008-10-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A single mutation at the sheet switch region results in conformational changes favoring lambda6 light-chain fibrillogenesis.
J.Mol.Biol., 396, 2010
3B5G
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BU of 3b5g by Molmil
Crystal Structure of the Unstable and Highly Fibrillogenic PRO7SER Mutant of the Recombinant Variable Domain 6AJL2
分子名称: ACETATE ION, AMYLOID LAMBDA 6 LIGHT CHAIN VARIABLE REGION PIP, GLYCEROL, ...
著者Hernandez-Santoyo, A, Rodriguez-Romero, A.
登録日2007-10-25
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A single mutation at the sheet switch region results in conformational changes favoring lambda6 light-chain fibrillogenesis.
J.Mol.Biol., 396, 2010
2LU9
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BU of 2lu9 by Molmil
NMR solution structure of recombinant Tamapin
分子名称: Potassium channel toxin alpha-KTx 5.4
著者del Rio-Portilla, F, Ramirez-Cordero, B.
登録日2012-06-08
公開日2013-12-11
最終更新日2014-07-02
実験手法SOLUTION NMR
主引用文献Cytotoxicity of recombinant tamapin and related toxin-like peptides on model cell lines.
Chem.Res.Toxicol., 27, 2014

 

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