2BML

Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors

Summary for 2BML

• Entry DOI: 10.2210/pdb2bml/pdb
• Related: 1GVM 1H8G 1HCX
• Descriptor: AUTOLYSIN, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HEXAETHYLENE GLYCOL, ... (7 entities in total)
• Functional Keywords: choline-binding domain, cell wall attachment, ofloxacin-like antibiotics
• Biological source: STREPTOCOCCUS PNEUMONIAE
• Cellular location: Secreted (Potential): P06653
• Total number of polymer chains: 2
• Total formula weight: 31437.73

Authors

Fernandez-Tornero, C.,Gimenez-Gallego, G.,Romero, A.,Garcia, E.,Pascual-Teresa, B.D.,Lopez, R. (deposition date: 2005-03-15, release date: 2005-03-30, Last modification date: 2023-12-13)

• Primary citation: Fernandez-Tornero, C.,Garcia, E.,Lopez, R.,Pascual-Teresa, B.D.,Gimenez-Gallego, G.,Romero, A.; Ofloxacin-Like Antibiotics Inhibit Pneumococcal Cell Wall-Degrading Virulence Factors; J.Biol.Chem., 280:19948-, 2005; PubMed: 15769740; DOI: 10.1074/JBC.M501236200

Experimental method

X-RAY DIFFRACTION (2.6 Å)