2BML
Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B1322 |
| Chain | Residue |
| A | LYS201 |
| A | TRP206 |
| B | LYS243 |
| B | TRP248 |
| B | P6G1320 |
| B | HOH2028 |
| B | HOH2033 |
| B | HOH2034 |
| B | HOH2035 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B1323 |
| Chain | Residue |
| A | LYS243 |
| A | TRP248 |
| B | LYS201 |
| B | TRP206 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B1324 |
| Chain | Residue |
| A | GLN285 |
| B | ASN281 |
| B | HOH2036 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE TRS A1319 |
| Chain | Residue |
| A | TRP220 |
| A | GLU275 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE TRS A1320 |
| Chain | Residue |
| A | TRP261 |
| A | TRP268 |
| A | TYR293 |
| A | LEU301 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE P6G A1321 |
| Chain | Residue |
| A | TRP241 |
| A | TRP248 |
| A | TYR269 |
| A | MET278 |
| A | ASP298 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE XED B1319 |
| Chain | Residue |
| B | SER212 |
| B | GLY213 |
| B | TYR214 |
| B | MET215 |
| B | TRP220 |
| B | TRP228 |
| B | GLU275 |
| B | HOH2009 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE P6G B1320 |
| Chain | Residue |
| A | PHE199 |
| A | TRP206 |
| A | TYR229 |
| A | GLU254 |
| B | TRP241 |
| B | TRP248 |
| B | TYR264 |
| B | TYR269 |
| B | ASP298 |
| B | SO41322 |
| B | HOH2030 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 B1321 |
| Chain | Residue |
| A | TYR207 |
| A | MET215 |
| B | TRP261 |
| B | TRP268 |
| B | HOH2032 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 38 |
| Details | Repeat: {"description":"Cell wall-binding 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"Cell wall-binding 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 38 |
| Details | Repeat: {"description":"Cell wall-binding 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 38 |
| Details | Repeat: {"description":"Cell wall-binding 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | Repeat: {"description":"Cell wall-binding 6"} |
| Chain | Residue | Details |
