2BML
Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AUTOLYSIN | polymer | 126 | 14892.5 | 2 | UniProt (P06653) Pfam (PF01473) | STREPTOCOCCUS PNEUMONIAE | N-ACETYLMURAMOYL-L-ALANINE AMIDASE, MUREIN, HYDROLASE, MUCOPEPTIDE AMINOHYDROLASE, CELL WALL HYDROLASE |
| 2 | C, D (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 3 | E, G (A, B) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 2 | Chemie (P6G) | |||
| 4 | F (B) | DEXTROFLOXACINE | non-polymer | 361.4 | 1 | Chemie (XED) | |||
| 5 | H (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | I, J, K (B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, B: 193 - 318 (UniProt: P06653)
| PDB | External Database | Details |
|---|---|---|
| Arg 304 | Lys 304 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29785.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1652.7 | |
| All* | Total formula weight | 31437.7 |
