3EG5
 
 | | Crystal structure of MDIA1-TSH GBD-FH3 in complex with CDC42-GMPPNP | | 分子名称: | Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Lammers, M, Meyer, S, Kuehlmann, D, Wittinghofer, A. | | 登録日 | 2008-09-10 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Specificity of Interactions between mDia Isoforms and Rho Proteins
J.Biol.Chem., 283, 2008
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2BAP
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2X25
 | | Free acetyl-CypA orthorhombic form | | 分子名称: | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A | | 著者 | Lammers, M, Neumann, H, Chin, J.W, James, L.C. | | 登録日 | 2010-01-11 | | 公開日 | 2010-03-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerization.
Nat.Chem.Biol., 6, 2010
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2X2A
 | | Free acetyl-CypA trigonal form | | 分子名称: | GLYCEROL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, SULFATE ION | | 著者 | Lammers, M, Neumann, H, Chin, J.W, James, L.C. | | 登録日 | 2010-01-12 | | 公開日 | 2010-03-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerization.
Nat.Chem.Biol., 6, 2010
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2X2D
 | | acetyl-CypA:HIV-1 N-term capsid domain complex | | 分子名称: | CAPSID PROTEIN P24, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A | | 著者 | Lammers, M, Neumann, H, Chin, J.W, James, L.C. | | 登録日 | 2010-01-12 | | 公開日 | 2010-03-23 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerisation
Nat.Chem.Biol., 6, 2010
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2X2C
 | | acetyl-CypA:cyclosporine complex | | 分子名称: | CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A | | 著者 | Lammers, M, Neumann, H, Chin, J.W, James, L.C. | | 登録日 | 2010-01-12 | | 公開日 | 2010-03-23 | | 最終更新日 | 2018-05-02 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerisation
Nat.Chem.Biol., 6, 2010
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4UWX
 | | Structure of liprin-alpha3 in complex with mDia1 Diaphanous- inhibitory domain | | 分子名称: | LIPRIN-ALPHA-3, NICKEL (II) ION, PROTEIN DIAPHANOUS HOMOLOG 1, ... | | 著者 | Brenig, J, de Boor, S, Knyphausen, P, Kuhlmann, N, Wroblowski, S, Baldus, L, Scislowski, L, Artz, O, Trauschies, P, Baumann, U, Neundorf, I, Lammers, M. | | 登録日 | 2014-08-15 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural and Biochemical Basis for the Inhibitory Effect of Liprin-Alpha3 on Mouse Diaphanous 1 (Mdia1) Function.
J.Biol.Chem., 290, 2015
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7P97
 | | Structure of 3-phospho-D-glycerate guanylyltransferase with product 3-GPPG bound | | 分子名称: | 3-(guanosine-5'-diphospho)-D-glycerate, 3-phospho-D-glycerate guanylyltransferase, CHLORIDE ION, ... | | 著者 | Palm, G.J, Berndt, L, Lammers, M. | | 登録日 | 2021-07-26 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Diversification by CofC and Control by CofD Govern Biosynthesis and Evolution of Coenzyme F 420 and Its Derivative 3PG-F 420.
Mbio, 13, 2022
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6Y9K
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8RPK
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8RPL
 | | AMP-forming acetyl-CoA synthetase from Chloroflexota bacterium with bound acetyl AMP | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Acetate--CoA ligase, MAGNESIUM ION, ... | | 著者 | Striska, K, Palm, G.J, Lammers, M. | | 登録日 | 2024-01-16 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Acetyl-CoA synthetase activity is enzymatically regulated by lysine acetylation using acetyl-CoA or acetyl-phosphate as donor molecule.
Nat Commun, 15, 2024
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7QE8
 | | Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 (SPINK1) | | 分子名称: | SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1 | | 著者 | Nagel, F, Palm, G.J, Delcea, M, Lammers, M. | | 登録日 | 2021-12-01 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
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7QE9
 | | Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 N34S (SPINK1 N34S) | | 分子名称: | SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1 | | 著者 | Nagel, F, Palm, G.J, Delcea, M, Lammers, M. | | 登録日 | 2021-12-01 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
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8S7Z
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1Z2C
 | | Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP | | 分子名称: | Diaphanous protein homolog 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Rose, R, Weyand, M, Lammers, M, Ishizaki, T, Ahmadian, M.R, Wittinghofer, A. | | 登録日 | 2005-03-08 | | 公開日 | 2005-05-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and mechanistic insights into the interaction between Rho and mammalian Dia.
Nature, 435, 2005
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5FR2
 | | Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178 | | 分子名称: | FARNESYL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kuhlmann, N, Wroblowski, S, Knyphausen, P, de Boor, S, Brenig, J, Zienert, A.Y, Meyer-Teschendorf, K, Praefcke, G.J.K, Nolte, H, Krueger, M, Schacherl, M, Baumann, U, James, L.C, Chin, J.W, Lammers, M. | | 登録日 | 2015-12-15 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation.
J.Biol.Chem., 291, 2016
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5FYQ
 | | Sirt2 in complex with a 13-mer trifluoroacetylated Ran peptide | | 分子名称: | NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, RAN AA 31-43, SULFATE ION, ... | | 著者 | Knyphausen, P, de Boor, S, Scislowski, L, Extra, A, Baldus, L, Schacherl, M, Baumann, U, Neundorf, I, Lammers, M. | | 登録日 | 2016-03-09 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Insights Into Lysine-Deacetylation of Natively Folded Substrate Proteins by Sirtuins.
J.Biol.Chem., 291, 2016
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7AC0
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7ATL
 | | EstCE1, a hydrolase with promiscuous acyltransferase activity | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Esterase, ... | | 著者 | Palm, G.J, Lammers, M, Berndt, L. | | 登録日 | 2020-10-30 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.478 Å) | | 主引用文献 | Discovery and Design of Family VIII Carboxylesterases as Highly Efficient Acyltransferases.
Angew.Chem.Int.Ed.Engl., 60, 2021
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5FR1
 | | Double acetylated RhoGDI-alpha in complex with RhoA-GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RHO GDP-DISSOCIATION INHIBITOR 1, ... | | 著者 | Kuhlmann, N, Wroblowski, S, Lammers, M. | | 登録日 | 2015-12-15 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Rhogdi Alpha Acetylation at K127 and K141 Affects Binding Towards Non-Prenylated Rhoa.
Biochemistry, 55, 2016
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9GKY
 | | Crystal Structure of Histone deacetylase (HdaH) from Vibrio cholerae in complex with decanoic acid | | 分子名称: | DECANOIC ACID, Histone deacetylase, IMIDAZOLE, ... | | 著者 | Graf, L.G, Schulze, S, Palm, G.J, Lammers, M. | | 登録日 | 2024-08-26 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Distribution and diversity of classical deacylases in bacteria
Nature Communications, 2024
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9GKV
 | | Crystal Structure of Deacetylase (HdaH) from Vibrio cholerae in complex with SAHA | | 分子名称: | ACETATE ION, Histone deacetylase, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ... | | 著者 | Graf, L.G, Schulze, S, Lammers, M, Palm, G.J. | | 登録日 | 2024-08-26 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Distribution and diversity of classical deacylases in bacteria
Nature Communications, 2024
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9GKX
 | | Crystal Structure of Rhizorhabdus wittichii Dimethoate hydrolase (DmhA) in complex with SAHA | | 分子名称: | Dimethoate hydrolase, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, OCTANOIC ACID (CAPRYLIC ACID), ... | | 著者 | Graf, L.G, Lammers, M, Schulze, S, Palm, G.J. | | 登録日 | 2024-08-26 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Distribution and diversity of classical deacylases in bacteria
Nature Communications, 2024
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9GKW
 | | Crystal Structure of Dimethoate hydrolase (DmhA) of Rhizorhabdus wittichii in complex with octanoic acid | | 分子名称: | Dimethoate hydrolase, OCTANOIC ACID (CAPRYLIC ACID), PENTAETHYLENE GLYCOL, ... | | 著者 | Graf, L.G, Schulze, S, Palm, G.J, Lammers, M. | | 登録日 | 2024-08-26 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Distribution and diversity of classical deacylases in bacteria
Nature Communications, 2024
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9GKZ
 | | Crystal Structure of Acetylpolyamine amidohydrolase (ApaH) from Pseudomonas sp. M30-35 | | 分子名称: | ACETATE ION, Acetylpolyamine amidohydrolase, CHLORIDE ION, ... | | 著者 | Graf, L.G, Schulze, S, Palm, G.J, Lammers, M. | | 登録日 | 2024-08-26 | | 公開日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Distribution and diversity of classical deacylases in bacteria
Nature Communications, 2024
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