1QSY
| DDATP-Trapped closed ternary complex of the large fragment of DNA Polymerase I from thermus aquaticus | 分子名称: | 2',3'-dideoxyadenosine triphosphate, 5'-D(*AP*TP*TP*GP*CP*GP*CP*CP*TP*P*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3', ... | 著者 | Li, Y, Mitaxov, V, Waksman, G. | 登録日 | 1999-06-24 | 公開日 | 1999-08-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
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1QSS
| DDGTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS | 分子名称: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3', ... | 著者 | Li, Y, Mitaxov, V, Waksman, G. | 登録日 | 1999-06-23 | 公開日 | 1999-08-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
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3C0F
| Crystal Structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source | 分子名称: | Uncharacterized protein AF_1514 | 著者 | Li, Y, Bahti, P, Shaw, N, Song, G, Yin, J, Zhu, J.-Y, Zhang, H, Xu, H, Wang, B.-C, Liu, Z.-J. | 登録日 | 2008-01-20 | 公開日 | 2008-02-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source. Proteins, 71, 2008
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2A3I
| Structural and Biochemical Mechanisms for the Specificity of Hormone Binding and Coactivator Assembly by Mineralocorticoid Receptor | 分子名称: | CORTICOSTERONE, Mineralocorticoid receptor, Nuclear receptor coactivator 1, ... | 著者 | Li, Y, Suino, K, Daugherty, J, Xu, H.E. | 登録日 | 2005-06-24 | 公開日 | 2005-07-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor Mol.Cell, 19, 2005
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5F59
| The crystal structure of MLL3 SET domain | 分子名称: | Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | 著者 | Li, Y, Lei, M, Chen, Y. | 登録日 | 2015-12-04 | 公開日 | 2016-02-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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5F6L
| The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L | 分子名称: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Li, Y, Lei, M, Chen, Y. | 登録日 | 2015-12-06 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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5F5E
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5F6K
| Crystal structure of the MLL3-Ash2L-RbBP5 complex | 分子名称: | Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Li, Y, Lei, M, Chen, Y. | 登録日 | 2015-12-06 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.411 Å) | 主引用文献 | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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3ETL
| RadA recombinase from Methanococcus maripaludis in complex with AMPPNP | 分子名称: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Li, Y, He, Y, Luo, Y. | 登録日 | 2008-10-08 | 公開日 | 2009-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr.,Sect.D, 65, 2009
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1HQR
| CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II | 分子名称: | HLA-DR ALPHA CHAIN, HLA-DR BETA CHAIN, MYELIN BASIC PROTEIN, ... | 著者 | Li, Y, Li, H, Dimasi, N, Schlievert, P, Mariuzza, R. | 登録日 | 2000-12-19 | 公開日 | 2001-01-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II. Immunity, 14, 2001
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3D34
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5KTQ
| LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO DCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, PROTEIN (DNA POLYMERASE I) | 著者 | Li, Y, Kong, Y, Korolev, S, Waksman, G. | 登録日 | 1998-09-22 | 公開日 | 1998-09-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates. Protein Sci., 7, 1998
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6QNX
| Structure of the SA2/SCC1/CTCF complex | 分子名称: | Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog, Transcriptional repressor CTCF | 著者 | Li, Y, Muir, K.W, Panne, D. | 登録日 | 2019-02-12 | 公開日 | 2020-01-22 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The structural basis for cohesin-CTCF-anchored loops. Nature, 578, 2020
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8GZ1
| Cryo-EM structure of human NaV1.6/beta1/beta2,apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Sodium channel protein type 8 subunit alpha, ... | 著者 | Li, Y, Jiang, D. | 登録日 | 2022-09-24 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of human Na V 1.6 channel reveals Na + selectivity and pore blockade by 4,9-anhydro-tetrodotoxin. Nat Commun, 14, 2023
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8GZ2
| Cryo-EM structure of human NaV1.6/beta1/beta2-4,9-anhydro-tetrodotoxin | 分子名称: | (1R,2S,3S,4R,5R,9S,11S,12S,14R)-7-amino-2,4,12-trihydroxy-2-(hydroxymethyl)-10,13,15-trioxa-6,8-diazapentacyclo[7.4.1.1~3,12~.0~5,11~.0~5,14~]pentadec-7-en-8-ium (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein type 8 subunit alpha, ... | 著者 | Li, Y, Jiang, D. | 登録日 | 2022-09-24 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of human Na V 1.6 channel reveals Na + selectivity and pore blockade by 4,9-anhydro-tetrodotoxin. Nat Commun, 14, 2023
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6H8Q
| Structural basis for Scc3-dependent cohesin recruitment to chromatin | 分子名称: | Cohesin subunit SCC3, DNA (5'-D(P*CP*TP*TP*TP*CP*GP*TP*TP*TP*CP*CP*TP*TP*GP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*CP*AP*AP*GP*GP*AP*AP*AP*CP*GP*AP*AP*AP*G)-3'), ... | 著者 | Li, Y, Muir, K, Panne, D. | 登録日 | 2018-08-03 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.631 Å) | 主引用文献 | Structural basis for Scc3-dependent cohesin recruitment to chromatin. Elife, 7, 2018
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6IUS
| A higher kcat Rubisco | 分子名称: | Ribulose-1,5-bisphosphate carboxylase/oxygenase | 著者 | Li, Y, Cai, Z. | 登録日 | 2018-11-30 | 公開日 | 2019-12-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | A higher kcat Rubisco To Be Published
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6IMQ
| Crystal structure of PML B1-box multimers | 分子名称: | CHLORIDE ION, Protein PML, ZINC ION | 著者 | Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G. | 登録日 | 2018-10-23 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis. Nat Commun, 10, 2019
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3EWA
| RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions | 分子名称: | DNA repair and recombination protein radA, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Li, Y, He, Y, Luo, Y. | 登録日 | 2008-10-14 | 公開日 | 2009-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis. Acta Crystallogr.,Sect.D, 65, 2009
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2QM4
| Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor | 分子名称: | Non-homologous end-joining factor 1 | 著者 | Li, Y, Chirgadze, D.Y, Sibanda, B.L, Bolanos-Garcia, V.M, Davies, O.R, Blundell, T.L. | 登録日 | 2007-07-14 | 公開日 | 2007-12-11 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ. Embo J., 27, 2008
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3CS8
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5DO2
| Complex structure of MERS-RBD bound with 4C2 antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C2 heavy chain, 4C2 light chain, ... | 著者 | Li, Y, Wan, Y, Liu, P, Zhao, J, Lu, G, Qi, J, Wang, Q, Lu, X, Wu, Y, Liu, W, Yuen, K.Y, Perlman, S, Gao, G.F, Yan, J. | 登録日 | 2015-09-10 | 公開日 | 2015-10-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.409 Å) | 主引用文献 | A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein. Cell Res., 25, 2015
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8GPX
| YFV_E_YD73Fab_postfusion | 分子名称: | Envelope protein, YD73Fab_H, YD73Fab_K | 著者 | Li, Y, Wu, L, Chai, Y, Qi, J, Yan, J, Gao, G.F. | 登録日 | 2022-08-27 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus. Innovation (N Y), 3, 2022
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3FYH
| Recombinase in complex with ADP and metatungstate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA repair and recombination protein radA, MAGNESIUM ION, ... | 著者 | Li, Y, He, Y, Luo, Y. | 登録日 | 2009-01-22 | 公開日 | 2009-09-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of an archaeal Rad51 homologue in complex with a metatungstate inhibitor. Biochemistry, 48, 2009
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2N7R
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