4CYE
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![BU of 4cye by Molmil](/molmil-images/mine/4cye) | Crystal structure of avian FAK FERM domain FAK31-405 at 3.2A | 分子名称: | FOCAL ADHESION KINASE 1 | 著者 | Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D. | 登録日 | 2014-04-10 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes. Proc.Natl.Acad.Sci.USA, 111, 2014
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6RFT
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![BU of 6rft by Molmil](/molmil-images/mine/6rft) | Crystal structure of Eis2 from Mycobacterium abscessus bound to Acetyl-CoA | 分子名称: | ACETYL COENZYME *A, Uncharacterized N-acetyltransferase D2E36_21790 | 著者 | Blaise, M, Kremer, L, Olieric, V, Alsarraf, H, Ung, K.L. | 登録日 | 2019-04-16 | 公開日 | 2019-07-10 | 最終更新日 | 2019-11-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus. Febs J., 286, 2019
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6RFX
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![BU of 6rfx by Molmil](/molmil-images/mine/6rfx) | Crystal structure of Eis2 from Mycobacterium abscessus | 分子名称: | ACETATE ION, CITRIC ACID, Eis2, ... | 著者 | Blaise, M, Kremer, L, Olieric, V, Alsarraf, H, Ung, K.L. | 登録日 | 2019-04-16 | 公開日 | 2019-07-10 | 最終更新日 | 2019-11-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus. Febs J., 286, 2019
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6RFY
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![BU of 6rfy by Molmil](/molmil-images/mine/6rfy) | Crystal structure of Eis2 form Mycobacterium abscessus | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Eis2, SULFATE ION | 著者 | Blaise, M, Kremer, L, Olieric, V, Alsarraf, H, Ung, K.L. | 登録日 | 2019-04-16 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus. Febs J., 286, 2019
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3ZDT
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![BU of 3zdt by Molmil](/molmil-images/mine/3zdt) | Crystal structure of basic patch mutant FAK FERM domain FAK31- 405 K216A, K218A, R221A, K222A | 分子名称: | FOCAL ADHESION KINASE 1 | 著者 | Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D. | 登録日 | 2012-11-30 | 公開日 | 2012-12-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes. Proc.Natl.Acad.Sci.USA, 111, 2014
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5T2V
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![BU of 5t2v by Molmil](/molmil-images/mine/5t2v) | Crystal structure of MSMEG_6753 a putative betaketoacyl-ACP reductase | 分子名称: | MAGNESIUM ION, Oxidoreductase, short chain dehydrogenase/reductase family protein | 著者 | Blaise, M, Van Wyk, N, Baneres-Roquet, F, Guerardel, Y, Kremer, L. | 登録日 | 2016-08-24 | 公開日 | 2017-02-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Binding of NADP(+) triggers an open-to-closed transition in a mycobacterial FabG beta-ketoacyl-ACP reductase. Biochem. J., 474, 2017
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3OF2
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![BU of 3of2 by Molmil](/molmil-images/mine/3of2) | Crystal structure of InhA_T266D:NADH complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Molle, V, Gulten, G, Vilcheze, C, Veyron-Churlet, R, Zanella-Cleon, I, Sacchettini, J.C, Jacobs Jr, W.R, Kremer, L. | 登録日 | 2010-08-13 | 公開日 | 2010-12-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis. Mol.Microbiol., 78, 2010
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2AHB
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![BU of 2ahb by Molmil](/molmil-images/mine/2ahb) | X-ray crystal structure of R46A,R161A mutant of Mycobacterium tuberculosis FabH | 分子名称: | Beta- ketoacyl-ACP synthase III | 著者 | Brown, A.K, Sridharan, S, Kremer, L, Lindenberg, S, Dover, L.G, Sacchettini, J.C, Besra, G.S. | 登録日 | 2005-07-27 | 公開日 | 2005-08-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the Mechanism of the Mycobacterium tuberculosis {beta}-Ketoacyl-Acyl Carrier Protein Synthase III mtFabH: FACTORS INFLUENCING CATALYSIS AND SUBSTRATE SPECIFICITY J.Biol.Chem., 280, 2005
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2AJ9
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![BU of 2aj9 by Molmil](/molmil-images/mine/2aj9) | X-ray crystal structure of W42A,R161A double mutant of Mycobacterium tuberculosis beta-ketoacyl-ACP synthase III | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase III | 著者 | Brown, A.K, Sridharan, S, Kremer, L, Lindenberg, S, Dover, L.G, Sacchettini, J.C, Besra, G.S. | 登録日 | 2005-08-01 | 公開日 | 2005-08-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Probing the Mechanism of the Mycobacterium tuberculosis beta-Ketoacyl-Acyl Carrier Protein Synthase III mtFabH: Factors Influencing Catalysis And Substrate Specificity. J.Biol.Chem., 280, 2005
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3OEY
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![BU of 3oey by Molmil](/molmil-images/mine/3oey) | Crystal structure of InhA_T266E:NADH complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Molle, V, Gulten, G, Vilcheze, C, Veyron-Churlet, R, Zanella-Cleon, I, Sacchettini, J.C, Jacobs Jr, W.R, Kremer, L. | 登録日 | 2010-08-13 | 公開日 | 2010-12-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis. Mol.Microbiol., 78, 2010
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3OEW
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![BU of 3oew by Molmil](/molmil-images/mine/3oew) | Crystal structure of wild-type InhA:NADH complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Molle, V, Gulten, G, Vilcheze, C, Veyron-Churlet, R, Zanella-Cleon, I, Sacchettini, J.C, Jacobs Jr, W.R, Kremer, L. | 登録日 | 2010-08-13 | 公開日 | 2010-12-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis. Mol.Microbiol., 78, 2010
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5OCJ
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![BU of 5ocj by Molmil](/molmil-images/mine/5ocj) | Crystal structure of Ag85C bound to cyclophostin 8beta inhibitor | 分子名称: | DIMETHYL SULFOXIDE, Diacylglycerol acyltransferase/mycolyltransferase Ag85C, methoxy-[(3~{R})-3-[(2~{R})-1-methoxy-1,3-bis(oxidanylidene)butan-2-yl]pentadecyl]phosphinic acid | 著者 | Viljoen, A, Richard, M, Nguyen, P.C, Spilling, C.D, Canaan, S, Cavalier, J.F, Blaise, M, Kremer, L. | 登録日 | 2017-07-03 | 公開日 | 2018-01-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cyclipostins and cyclophostin analogs inhibit the antigen 85C from J. Biol. Chem., 293, 2018
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5OVJ
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![BU of 5ovj by Molmil](/molmil-images/mine/5ovj) | Structure of the apo form of Mycobacterium smegmatis MabA | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] reductase FabG, SULFATE ION | 著者 | Kussau, T, Van Wyk, N, Viljoen, A, Olieric, V, Flipo, M, Kremer, L, Blaise, M. | 登録日 | 2017-08-29 | 公開日 | 2018-02-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural rearrangements occurring upon cofactor binding in the Mycobacterium smegmatis beta-ketoacyl-acyl carrier protein reductase MabA. Acta Crystallogr D Struct Biol, 74, 2018
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5OVL
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![BU of 5ovl by Molmil](/molmil-images/mine/5ovl) | crystal structure of MabA bound to NADP+ from M. smegmatis | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] reductase FabG, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Kussau, T, Van Wyk, N, Viljoen, A, Olieric, V, Flipo, M, Kremer, L, Blaise, M. | 登録日 | 2017-08-29 | 公開日 | 2018-02-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural rearrangements occurring upon cofactor binding in the Mycobacterium smegmatis beta-ketoacyl-acyl carrier protein reductase MabA. Acta Crystallogr D Struct Biol, 74, 2018
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5OVY
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![BU of 5ovy by Molmil](/molmil-images/mine/5ovy) | Crystal structure of MAB_4384 tetR | 分子名称: | Putative transcriptional regulator, TetR family | 著者 | Richard, M, Gutierrez, A.V, Viljoen, A, Ghigo, E, Blaise, M, Kremer, L. | 登録日 | 2017-08-30 | 公開日 | 2018-03-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump inMycobacterium abscessus. Front Microbiol, 9, 2018
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5OVK
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![BU of 5ovk by Molmil](/molmil-images/mine/5ovk) | Crystal structure MabA bound to NADPH from M. smegmatis | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] reductase FabG, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Kussau, T, Van Wyk, N, Viljoen, A, Olieric, V, Flipo, M, Kremer, L, Blaise, M. | 登録日 | 2017-08-29 | 公開日 | 2018-02-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural rearrangements occurring upon cofactor binding in the Mycobacterium smegmatis beta-ketoacyl-acyl carrier protein reductase MabA. Acta Crystallogr D Struct Biol, 74, 2018
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2QJ3
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![BU of 2qj3 by Molmil](/molmil-images/mine/2qj3) | Mycobacterium tuberculosis FabD | 分子名称: | Malonyl CoA-acyl carrier protein transacylase, NICKEL (II) ION | 著者 | Ghadbane, H, Brown, A.K, Kremer, L, Besra, G.S, Futterer, K. | 登録日 | 2007-07-06 | 公開日 | 2007-09-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT). Acta Crystallogr.,Sect.F, 63, 2007
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1R88
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![BU of 1r88 by Molmil](/molmil-images/mine/1r88) | The crystal structure of Mycobacterium tuberculosis MPT51 (FbpC1) | 分子名称: | MPT51/MPB51 antigen | 著者 | Wilson, R.A, Maughan, W.N, Kremer, L, Besra, G.S, Futterer, K. | 登録日 | 2003-10-23 | 公開日 | 2003-12-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha/beta hydrolases. J.Mol.Biol., 335, 2004
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4V12
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![BU of 4v12 by Molmil](/molmil-images/mine/4v12) | Crystal structure of the MSMEG_6754 dehydratase from Mycobacterium smegmatis | 分子名称: | (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAOC LIKE DOMAIN PROTEIN | 著者 | Blaise, M. | 登録日 | 2014-09-23 | 公開日 | 2015-03-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A New Dehydratase Conferring Innate Resistance to Thiacetazone and Intra-Amoebal Survival of Mycobacterium Smegmatis. Mol.Microbiol., 96, 2015
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5I7N
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![BU of 5i7n by Molmil](/molmil-images/mine/5i7n) | MaoC-like dehydratase | 分子名称: | MaoC-like dehydratase | 著者 | Blaise, M. | 登録日 | 2016-02-18 | 公開日 | 2016-07-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent. Proc.Natl.Acad.Sci.USA, 113, 2016
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5LD8
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![BU of 5ld8 by Molmil](/molmil-images/mine/5ld8) | |
7N12
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![BU of 7n12 by Molmil](/molmil-images/mine/7n12) | Crystal structure of the M. abscessus LeuRS editing domain in complex with epetraborole-AMP adduct | 分子名称: | Leucine--tRNA ligase, SULFATE ION, [(1S,5R,6R,7'S,8R)-7'-(aminomethyl)-6-(6-aminopurin-9-yl)-2'-(3-oxidanylpropoxy)spiro[2,4,7-trioxa-3-boranuidabicyclo[3.3.0]octane-3,9'-8-oxa-9-boranuidabicyclo[4.3.0]nona-1(6),2,4-triene]-8-yl]methyl dihydrogen phosphate | 著者 | Kalthoff, E, Schmeing, M. | 登録日 | 2021-05-26 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline. Plos Pathog., 17, 2021
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7N11
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![BU of 7n11 by Molmil](/molmil-images/mine/7n11) | |
7Q3A
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![BU of 7q3a by Molmil](/molmil-images/mine/7q3a) | Crystal structure of MAB_4324 a tandem repeat GNAT from Mycobacterium abscessus | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... | 著者 | Blaise, M, Alsarraf, M.A.B. | 登録日 | 2021-10-27 | 公開日 | 2022-05-04 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biochemical, structural, and functional studies reveal that MAB_4324c from Mycobacterium abscessus is an active tandem repeat N-acetyltransferase. Febs Lett., 596, 2022
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3F4B
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![BU of 3f4b by Molmil](/molmil-images/mine/3f4b) | |