7N11
Crystal structure of the M. abscessus LeuRS editing domain in complex with epetraborole-AMP adduct
Summary for 7N11
| Entry DOI | 10.2210/pdb7n11/pdb |
| Descriptor | Leucine--tRNA ligase, SULFATE ION (3 entities in total) |
| Functional Keywords | oxaborole, inhibitor, complex, antibiotic, ligase-ligase inhibitor complex, ligase/ligase inhibitor |
| Biological source | Mycobacteroides abscessus |
| Total number of polymer chains | 1 |
| Total formula weight | 21312.47 |
| Authors | Kalthoff, E.,Schmeing, M. (deposition date: 2021-05-26, release date: 2021-10-06, Last modification date: 2023-10-18) |
| Primary citation | Sullivan, J.R.,Lupien, A.,Kalthoff, E.,Hamela, C.,Taylor, L.,Munro, K.A.,Schmeing, T.M.,Kremer, L.,Behr, M.A. Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline. Plos Pathog., 17:e1009965-e1009965, 2021 Cited by PubMed: 34637487DOI: 10.1371/journal.ppat.1009965 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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