3OEW

Crystal structure of wild-type InhA:NADH complex

Summary for 3OEW

• Entry DOI: 10.2210/pdb3oew/pdb
• Related: 3OEW 3OEY 3OF2
• Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: enoly-reductase, oxidoreductase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 29336.38

Authors

Molle, V.,Gulten, G.,Vilcheze, C.,Veyron-Churlet, R.,Zanella-Cleon, I.,Sacchettini, J.C.,Jacobs Jr, W.R.,Kremer, L. (deposition date: 2010-08-13, release date: 2010-12-01, Last modification date: 2024-02-21)

• Primary citation: Molle, V.,Gulten, G.,Vilcheze, C.,Veyron-Churlet, R.,Zanella-Cleon, I.,Sacchettini, J.C.,Jacobs Jr, W.R.,Kremer, L.; Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis.; Mol.Microbiol., 78:1591-1605, 2010; PubMed: 21143326; DOI: 10.1111/j.1365-2958.2010.07446.x

Experimental method

X-RAY DIFFRACTION (2.2 Å)