5OCJ
Crystal structure of Ag85C bound to cyclophostin 8beta inhibitor
Summary for 5OCJ
Entry DOI | 10.2210/pdb5ocj/pdb |
Descriptor | Diacylglycerol acyltransferase/mycolyltransferase Ag85C, methoxy-[(3~{R})-3-[(2~{R})-1-methoxy-1,3-bis(oxidanylidene)butan-2-yl]pentadecyl]phosphinic acid, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | ag85c, mycolicate, mycomembrane, tmm, tdm, transferase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Cellular location | Secreted : P9WQN9 |
Total number of polymer chains | 2 |
Total formula weight | 67482.88 |
Authors | Viljoen, A.,Richard, M.,Nguyen, P.C.,Spilling, C.D.,Canaan, S.,Cavalier, J.F.,Blaise, M.,Kremer, L. (deposition date: 2017-07-03, release date: 2018-01-24, Last modification date: 2024-01-17) |
Primary citation | Viljoen, A.,Richard, M.,Nguyen, P.C.,Fourquet, P.,Camoin, L.,Paudal, R.R.,Gnawali, G.R.,Spilling, C.D.,Cavalier, J.F.,Canaan, S.,Blaise, M.,Kremer, L. Cyclipostins and cyclophostin analogs inhibit the antigen 85C from J. Biol. Chem., 293:2755-2769, 2018 Cited by PubMed: 29301937DOI: 10.1074/jbc.RA117.000760 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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