5OCJ

Crystal structure of Ag85C bound to cyclophostin 8beta inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Diacylglycerol acyltransferase/mycolyltransferase Ag85C	polymer	303	33242.8	2	UniProt (P9WQN9) Pfam (PF00756)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	DGAT,Acyl-CoA:diacylglycerol acyltransferase,Antigen 85 complex C,Ag85C,Fibronectin-binding protein C,Fbps C
2	C, E (A, B)	methoxy-[(3~{R})-3-[(2~{R})-1-methoxy-1,3-bis(oxidanylidene)butan-2-yl]pentadecyl]phosphinic acid	non-polymer		420.5	2	Chemie (9SW)
3	D, F (A, B)	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS)
4	G, H (A, B)	water	water		18.0	533	Chemie (HOH)

Sequence modifications

A, B: 1 - 294 (UniProt: P9WQN9)

PDB	External Database	Details
Met 0	-	initiating methionine
Leu 295	-	expression tag
Glu 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66485.6
Non-Polymers*	Number of molecules	4
	Total formula weight	997.3
All*	Total formula weight	67482.9

*Water molecules are not included.