5OCJ
Crystal structure of Ag85C bound to cyclophostin 8beta inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Diacylglycerol acyltransferase/mycolyltransferase Ag85C | polymer | 303 | 33242.8 | 2 | UniProt (P9WQN9) Pfam (PF00756) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | DGAT,Acyl-CoA:diacylglycerol acyltransferase,Antigen 85 complex C,Ag85C,Fibronectin-binding protein C,Fbps C |
2 | A, B | methoxy-[(3~{R})-3-[(2~{R})-1-methoxy-1,3-bis(oxidanylidene)butan-2-yl]pentadecyl]phosphinic acid | non-polymer | 420.5 | 2 | Chemie (9SW) | |||
3 | A, B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
4 | water | water | 18.0 | 533 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 294 (UniProt: P9WQN9)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Leu 295 | - | expression tag |
Glu 296 | - | expression tag |
His 297 | - | expression tag |
His 298 | - | expression tag |
His 299 | - | expression tag |
His 300 | - | expression tag |
His 301 | - | expression tag |
His 302 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 66485.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 997.3 | |
All* | Total formula weight | 67482.9 |