5OCJ
Crystal structure of Ag85C bound to cyclophostin 8beta inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004144 | molecular_function | diacylglycerol O-acyltransferase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006869 | biological_process | lipid transport |
| A | 0009247 | biological_process | glycolipid biosynthetic process |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0035375 | molecular_function | zymogen binding |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0050348 | molecular_function | trehalose O-mycolyltransferase activity |
| A | 0071769 | biological_process | mycolate cell wall layer assembly |
| B | 0004144 | molecular_function | diacylglycerol O-acyltransferase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006869 | biological_process | lipid transport |
| B | 0009247 | biological_process | glycolipid biosynthetic process |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0035375 | molecular_function | zymogen binding |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0050348 | molecular_function | trehalose O-mycolyltransferase activity |
| B | 0071769 | biological_process | mycolate cell wall layer assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue 9SW A 401 |
| Chain | Residue |
| A | GLY39 |
| A | LEU40 |
| A | SER124 |
| A | PRO223 |
| A | LEU227 |
| A | HIS260 |
| A | TRP265 |
| A | HOH501 |
| B | 9SW401 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 402 |
| Chain | Residue |
| A | PHE26 |
| A | GLY29 |
| A | GLY30 |
| A | SER65 |
| A | LYS111 |
| A | GLY112 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue 9SW B 401 |
| Chain | Residue |
| A | ALA165 |
| A | ILE222 |
| A | PRO223 |
| A | PHE226 |
| A | 9SW401 |
| B | GLY39 |
| B | LEU40 |
| B | ARG41 |
| B | SER124 |
| B | ILE222 |
| B | PRO223 |
| B | PHE226 |
| B | LEU227 |
| B | HIS260 |
| B | TRP265 |
| B | HOH501 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue DMS B 402 |
| Chain | Residue |
| B | ASP79 |
| B | TYR81 |
| B | MET177 |
| B | HOH656 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:10655617 |
| Chain | Residue | Details |
| A | SER124 | |
| B | SER124 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:10655617 |
| Chain | Residue | Details |
| A | GLU228 | |
| A | HIS260 | |
| B | GLU228 | |
| B | HIS260 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LEU40 | |
| B | LEU40 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER124 | |
| A | ASN152 | |
| A | LEU230 | |
| A | THR237 | |
| A | HIS260 | |
| B | SER124 | |
| B | ASN152 | |
| B | LEU230 | |
| B | THR237 | |
| B | HIS260 |
