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4DBL
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BU of 4dbl by Molmil
Crystal structure of E159Q mutant of BtuCDF
分子名称: PHOSPHATE ION, SULFATE ION, Vitamin B12 import ATP-binding protein BtuD, ...
著者Korkhov, V.M, Mireku, S.M, Hvorup, R.N, Locher, K.P.
登録日2012-01-16
公開日2012-03-07
最終更新日2012-05-23
実験手法X-RAY DIFFRACTION (3.493 Å)
主引用文献Asymmetric states of vitamin B12 transporter BtuCD are not discriminated by its cognate substrate binding protein BtuF.
Febs Lett., 586, 2012
4R9U
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BU of 4r9u by Molmil
Structure of vitamin B12 transporter BtuCD in a nucleotide-bound outward facing state
分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Korkhov, V.M, Mireku, S.A, Veprintsev, D.B, Locher, K.P.
登録日2014-09-08
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.785 Å)
主引用文献Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F.
Nat.Struct.Mol.Biol., 21, 2014
4FI3
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BU of 4fi3 by Molmil
Structure of vitamin B12 transporter BtuCD-F in a nucleotide-bound state
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Vitamin B12 import ATP-binding protein BtuD, ...
著者Korkhov, V.M, Mireku, S.A, Locher, K.P.
登録日2012-06-07
公開日2012-09-19
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.466 Å)
主引用文献Structure of AMP-PNP-bound vitamin B12 transporter BtuCD-F.
Nature, 490, 2012
6R4P
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BU of 6r4p by Molmil
Structure of a soluble domain of adenylyl cyclase bound to an activated stimulatory G protein
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Korkhov, V.M, Qi, C.
登録日2019-03-22
公開日2019-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
Science, 364, 2019
7NUR
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BU of 7nur by Molmil
Structure of the Toxoplasma gondii kinase Ron13, kinase-dead mutant
分子名称: Protein kinase domain-containing protein
著者Korkhov, V.M, Mehta, V.
登録日2021-03-13
公開日2021-05-26
最終更新日2021-07-07
実験手法ELECTRON MICROSCOPY (3.125 Å)
主引用文献Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion.
Nat Commun, 12, 2021
6RMG
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BU of 6rmg by Molmil
Structure of PTCH1 bound to a modified Hedgehog ligand ShhN-C24II
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Korkhov, V.M, Qi, C.
登録日2019-05-06
公開日2019-10-09
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of sterol recognition by human hedgehog receptor PTCH1.
Sci Adv, 5, 2019
6TBU
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BU of 6tbu by Molmil
Structure of Drosophila melanogaster Dispatched
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Korkhov, V.M, Cannac, F.
登録日2019-11-04
公開日2020-06-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Cryo-EM structure of the Hedgehog release protein Dispatched.
Sci Adv, 6, 2020
6TD6
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BU of 6td6 by Molmil
Structure of Drosophila melanogaster Dispatched bound to a modified Hedgehog ligand, HhN-C85II
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein dispatched, ...
著者Korkhov, V.M, Cannac, F.
登録日2019-11-07
公開日2020-06-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.76 Å)
主引用文献Cryo-EM structure of the Hedgehog release protein Dispatched.
Sci Adv, 6, 2020
6R3Q
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BU of 6r3q by Molmil
The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Korkhov, V.M, Qi, C.
登録日2019-03-20
公開日2019-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
Science, 364, 2019
8JPS
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BU of 8jps by Molmil
Structure of Duffy Antigen Receptor for Chemokines (DARC)/ACKR1 in complex with the chemokine, CCL7 (Composite map)
分子名称: Atypical chemokine receptor 1, C-C motif chemokine 7
著者Banerjee, R, Khanppnavar, B, Maharana, J, Saha, S, Korkhov, V.M, Shukla, A.K.
登録日2023-06-12
公開日2024-07-31
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor.
Cell, 187, 2024
8BUZ
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BU of 8buz by Molmil
Structure of Adenylyl cyclase 8 bound to stimulatory G-protein, Ca2+/Calmodulin, Forskolin and MANT-GTP
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 8, FORSKOLIN, ...
著者Khanppnavar, B, Korkhov, V.M, Mehta, V.
登録日2022-12-01
公開日2023-12-13
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics.
Embo Rep., 25, 2024
8BV5
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BU of 8bv5 by Molmil
Focus refinement of soluble domain of Adenylyl cyclase 8 bound to stimulatory G protein, Forskolin, ATPalphaS, and Ca2+/Calmodulin in lipid nanodisc conditions
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 8, FORSKOLIN, ...
著者Khanppnavar, B, Korkhov, V.M.
登録日2023-01-04
公開日2024-01-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics.
Embo Rep., 25, 2024
6R4O
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BU of 6r4o by Molmil
Structure of a truncated adenylyl cyclase bound to MANT-GTP, forskolin and an activated stimulatory Galphas protein
分子名称: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, ...
著者Qi, C, Sorrentino, S, Medalia, O, Korkhov, V.M.
登録日2019-03-22
公開日2019-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
Science, 364, 2019
7PD4
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BU of 7pd4 by Molmil
structure of Adenylyl cyclase 9 in complex with MANT-GTP
分子名称: Adenylate cyclase 9
著者Qi, C, Korkhov, V.M.
登録日2021-08-04
公開日2022-01-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PD8
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BU of 7pd8 by Molmil
Structure of Adenylyl cyclase 9 in complex with DARPin C4 and MANT-GTP
分子名称: Adenylate cyclase 9, DARPin C4
著者Qi, C, Korkhov, V.M.
登録日2021-08-04
公開日2022-01-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDH
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BU of 7pdh by Molmil
structure of adenylyl cyclase 9 in complex with DARPin C4 and ATP-aS
分子名称: Adenylate cyclase 9, DARPin C4
著者Qi, C, Korkhov, V.M.
登録日2021-08-05
公開日2022-01-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDD
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BU of 7pdd by Molmil
Focus refinement of soluble domain of Adenylyl cyclase 9 in complex with DARPin C4 and MANT-GTP
分子名称: Adenylate cyclase 9, DARPin C4
著者Qi, C, Korkhov, V.M.
登録日2021-08-05
公開日2022-01-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDG
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BU of 7pdg by Molmil
structure of adenylyl cyclase 9 in complex with DARPin C4 and ATP-aS
分子名称: Adenylate cyclase 9, DARPin C4
著者Qi, C, Korkhov, V.M.
登録日2021-08-05
公開日2022-01-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDE
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BU of 7pde by Molmil
Structure of Adenylyl cyclase 9 in complex with Gs protein alpha subunit and MANT-GTP
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Qi, C, Korkhov, V.M.
登録日2021-08-05
公開日2022-01-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDF
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BU of 7pdf by Molmil
focus refinement of soluble domain of adenylyl cyclase 9 in complex with Gs protein alpha subunit and MANT-GTP
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Qi, C, Korkhov, V.M.
登録日2021-08-05
公開日2022-01-26
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
8QK6
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BU of 8qk6 by Molmil
Connexin-32 hemichannel upon addition of 2-aminoetoxydiphenyl borate
分子名称: CHOLESTEROL, Gap junction beta-1 protein
著者Lavriha, P, Korkhov, V.M, Han, Y.
登録日2023-09-14
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
To Be Published
8QKI
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BU of 8qki by Molmil
Connexin-32 hemichannel upon addition of mefloquine
分子名称: CHOLESTEROL, Gap junction beta-1 protein
著者Lavriha, P, Korkhov, V.M, Han, Y.
登録日2023-09-15
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
To Be Published
8QKO
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BU of 8qko by Molmil
Connexin-43 gap junction channel in complex with mefloquine
分子名称: Gap junction alpha-1 protein
著者Lavriha, P, Korkhov, V.M, Han, Y.
登録日2023-09-16
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
To Be Published
8QJF
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BU of 8qjf by Molmil
Connexin-32 gap junction channel in complex with 2-aminoethoxydiphenyl borate
分子名称: CHOLESTEROL, Gap junction beta-1 protein
著者Lavriha, P, Korkhov, V.M, Han, Y.
登録日2023-09-13
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
To Be Published
8QJH
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BU of 8qjh by Molmil
Connexin-32 gap junction channel in complex with mefloquine
分子名称: Gap junction beta-1 protein
著者Lavriha, P, Korkhov, V.M, Han, Y.
登録日2023-09-13
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
To Be Published

 

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