6R4O

Structure of a truncated adenylyl cyclase bound to MANT-GTP, forskolin and an activated stimulatory Galphas protein

Summary for 6R4O

• Entry DOI: 10.2210/pdb6r4o/pdb
• EMDB information: 4721
• Descriptor: Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: adenylyl cyclase, g protein, mant-gtp, forskolin, membrane protein
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 2
• Total formula weight: 219696.01

Authors

Qi, C.,Sorrentino, S.,Medalia, O.,Korkhov, V.M. (deposition date: 2019-03-22, release date: 2019-05-08, Last modification date: 2019-11-06)

• Primary citation: Qi, C.,Sorrentino, S.,Medalia, O.,Korkhov, V.M.; The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.; Science, 364:389-394, 2019; PubMed: 31023924; DOI: 10.1126/science.aav0778

Experimental method

ELECTRON MICROSCOPY (4.2 Å)