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8QJH

Connexin-32 gap junction channel in complex with mefloquine

Summary for 8QJH
Entry DOI10.2210/pdb8qjh/pdb
EMDB information18447
DescriptorGap junction beta-1 protein (1 entity in total)
Functional Keywordscomplex, membrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains12
Total formula weight384786.40
Authors
Lavriha, P.,Korkhov, V.M.,Han, Y. (deposition date: 2023-09-13, release date: 2024-09-25, Last modification date: 2024-10-16)
Primary citationLavriha, P.,Han, Y.,Ding, X.,Qi, C.,Vaithia, A.,Korkhov, V.M.
Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.91 Å)
Structure validation

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PDB entries from 2024-11-06

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