8QKI
Connexin-32 hemichannel upon addition of mefloquine
Summary for 8QKI
Entry DOI | 10.2210/pdb8qki/pdb |
EMDB information | 18463 |
Descriptor | Gap junction beta-1 protein, CHOLESTEROL (2 entities in total) |
Functional Keywords | connexin, hemichannel, mefloqine, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 194713.12 |
Authors | Lavriha, P.,Korkhov, V.M.,Han, Y. (deposition date: 2023-09-15, release date: 2024-09-25, Last modification date: 2024-11-20) |
Primary citation | Lavriha, P.,Han, Y.,Ding, X.,Qi, C.,Vaithia, A.,Korkhov, V.M. Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.46 Å) |
Structure validation
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