8QKI

Connexin-32 hemichannel upon addition of mefloquine

Summary for 8QKI

• Entry DOI: 10.2210/pdb8qki/pdb
• EMDB information: 18463
• Descriptor: Gap junction beta-1 protein, CHOLESTEROL (2 entities in total)
• Functional Keywords: connexin, hemichannel, mefloqine, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 194713.12

Authors

Lavriha, P.,Korkhov, V.M.,Han, Y. (deposition date: 2023-09-15, release date: 2024-09-25)

• Primary citation: Lavriha, P.,Han, Y.,Ding, X.,Qi, C.,Vaithia, A.,Korkhov, V.M.; Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.46 Å)