8QKO

Connexin-43 gap junction channel in complex with mefloquine

Summary for 8QKO

• Entry DOI: 10.2210/pdb8qko/pdb
• EMDB information: 18468
• Descriptor: Gap junction alpha-1 protein (1 entity in total)
• Functional Keywords: connexin, gap junction channel, complex, mefloquine, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 516736.03

Authors

Lavriha, P.,Korkhov, V.M.,Han, Y. (deposition date: 2023-09-16, release date: 2024-09-25, Last modification date: 2024-10-23)

• Primary citation: Lavriha, P.,Han, Y.,Ding, X.,Qi, C.,Vaithia, A.,Korkhov, V.M.; Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.73 Å)