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8QKO

Connexin-43 gap junction channel in complex with mefloquine

Summary for 8QKO
Entry DOI10.2210/pdb8qko/pdb
EMDB information18468
DescriptorGap junction alpha-1 protein (1 entity in total)
Functional Keywordsconnexin, gap junction channel, complex, mefloquine, membrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains12
Total formula weight516736.03
Authors
Lavriha, P.,Korkhov, V.M.,Han, Y. (deposition date: 2023-09-16, release date: 2024-09-25, Last modification date: 2024-10-23)
Primary citationLavriha, P.,Han, Y.,Ding, X.,Qi, C.,Vaithia, A.,Korkhov, V.M.
Two distinct mechanisms of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.73 Å)
Structure validation

228677

PDB entries from 2024-12-11

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