6UI2
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4M47
| structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA polymerase beta, MAGNESIUM ION, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-06 | 公開日 | 2014-01-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine. J.Biol.Chem., 289, 2014
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4MF2
| Structure of human DNA polymerase beta complexed with O6MG as the template base in a 1-nucleotide gapped DNA | 分子名称: | DNA polymerase beta, SODIUM ION, synthetic downstream primer, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-27 | 公開日 | 2014-04-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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4MFF
| Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable TTP | 分子名称: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA polymerase beta, MAGNESIUM ION, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-27 | 公開日 | 2014-04-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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4MF8
| Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template O6MG and incoming CTP | 分子名称: | DNA polymerase beta, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-27 | 公開日 | 2014-08-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structures of human DNA polymerase beta inserting bases opposite templating O6MG To be Published
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4MFC
| Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable CTP | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA polymerase beta, MAGNESIUM ION, ... | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | 登録日 | 2013-08-27 | 公開日 | 2014-04-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta. J.Am.Chem.Soc., 136, 2014
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6PL8
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6PLC
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6PKZ
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6PL7
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4JCH
| OSH4 bound to an electrophilic oxysterol | 分子名称: | (3beta,9beta,22R,25R)-3-hydroxyfurost-5-en-27-yl propanoate, Protein KES1 | 著者 | Koag, M.C, Kou, Y.I, Monzingo, A.F, Lee, S. | 登録日 | 2013-02-21 | 公開日 | 2014-03-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of OSH4 bound to an electrophilic oxysterol To be Published
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4F4B
| Structure of OSH4 with a cholesterol analog | 分子名称: | (3beta,9beta,25R)-3-hydroxy-26-iodocholest-5-ene-16,22-dione, Protein KES1 | 著者 | Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S. | 登録日 | 2012-05-10 | 公開日 | 2013-05-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4. Steroids, 78, 2013
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4FES
| Structure of OSH4 in complex with cholesterol analogs | 分子名称: | (3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2S,6S)-6-methyl-3-oxooctan-2-yl]-1,2,3,4,7,8,9,10,11,12,13,14,15,17-tetradecahydro-16H-cyclopenta[a]phenanthren-16-one, Protein KES1 | 著者 | Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S. | 登録日 | 2012-05-30 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4. Steroids, 78, 2013
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4TUR
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4TUS
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4TUQ
| Human DNA polymerase beta inserting dCMPNPP opposite GG template (GG0b). | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*AP*TP*GP*GP*GP*C)-3'), ... | 著者 | Koag, M.C, Lee, S. | 登録日 | 2014-06-24 | 公開日 | 2014-10-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.367 Å) | 主引用文献 | Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta. J.Biol.Chem., 289, 2014
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4TUP
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4O5C
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4PGY
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4PHE
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4O5E
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4O5K
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4PGX
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4PGQ
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4PHP
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