4PGX
Structure of human DNA polymerase beta complexed with G in the template base paired with incoming non-hydrolyzable TTP and MANGANESE
Summary for 4PGX
Entry DOI | 10.2210/pdb4pgx/pdb |
Descriptor | DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (8 entities in total) |
Functional Keywords | human dna polymerase, nucleotidyl synthtsis, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 47284.66 |
Authors | Koag, M.C.,Lee, S. (deposition date: 2014-05-03, release date: 2014-09-24, Last modification date: 2023-12-27) |
Primary citation | Koag, M.C.,Nam, K.,Lee, S. The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase beta. Nucleic Acids Res., 42:11233-11245, 2015 Cited by PubMed: 25200079DOI: 10.1093/nar/gku789 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.077 Å) |
Structure validation
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