6UI2

Structure of human DNA polymerase eta complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP

Summary for 6UI2

• Entry DOI: 10.2210/pdb6ui2/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(FMG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total)
• Functional Keywords: dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 55346.63

Authors

Koag, M.C.,Lee, S. (deposition date: 2019-09-30, release date: 2020-01-15, Last modification date: 2023-10-11)

• Primary citation: Koag, M.C.,Jung, H.,Kou, Y.,Lee, S.; Bypass of the Major Alkylative DNA Lesion by Human DNA Polymerase eta.; Molecules, 24:-, 2019; PubMed: 31683505; DOI: 10.3390/molecules24213928

Experimental method

X-RAY DIFFRACTION (2.35 Å)