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6UI2

Structure of human DNA polymerase eta complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP

Functional Information from GO Data
ChainGOidnamespacecontents
A0003684molecular_functiondamaged DNA binding
A0006281biological_processDNA repair
Functional Information from PDB Data
site_idAC1
Number of Residues20
Detailsbinding site for residue 0KX A 501
ChainResidue
AASP13
AARG55
AARG61
AASP115
ALYS231
AMG502
AMG503
AHOH606
AHOH623
AHOH642
PDT8
AMET14
TFMG4
AASP15
ACYS16
APHE17
APHE18
AILE48
AALA49
ATYR52

site_idAC2
Number of Residues5
Detailsbinding site for residue MG A 502
ChainResidue
AASP13
AMET14
AASP115
A0KX501
AMG503

site_idAC3
Number of Residues6
Detailsbinding site for residue MG A 503
ChainResidue
AASP13
AASP115
AGLU116
A0KX501
AMG502
PDT8

site_idAC4
Number of Residues10
Detailsbinding site for residue GOL A 504
ChainResidue
AARG24
AGLN25
APRO244
APHE247
ASER248
AGLY276
AGLU277
AHOH610
AHOH624
AHOH638

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO
ChainResidueDetails
AASP13
AMET14
AASP115
AGLU116

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:27284197
ChainResidueDetails
AARG61

227561

PDB entries from 2024-11-20

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