8JH4
 
 | | RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome | | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. | | 登録日 | 2023-05-22 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
|
|
8JH2
 | | RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome | | 分子名称: | DNA (218-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ... | | 著者 | Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. | | 登録日 | 2023-05-22 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
|
|
8JH3
 | | RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome | | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. | | 登録日 | 2023-05-22 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
|
|
1IY6
 | | Solution structure of OMSVP3 variant, P14C/N39C | | 分子名称: | OMSVP3 | | 著者 | Hemmi, H, Kumazaki, T, Yamazaki, T, Kojima, S, Yoshida, T, Kyogoku, Y, Katsu, M, Yokosawa, H, Miura, K, Kobayashi, Y. | | 登録日 | 2002-07-23 | | 公開日 | 2003-03-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Inhibitory Specificity Change of Ovomucoid Third Domain of the Silver Pheasant upon Introduction of an Engineered Cys14-Cys39 Bond
BIOCHEMISTRY, 42, 2003
|
|
1IY5
 | | Solution structure of wild type OMSVP3 | | 分子名称: | OMSVP3 | | 著者 | Hemmi, H, Kumazaki, T, Yamazaki, T, Kojima, S, Yoshida, T, Kyogoku, Y, Katsu, M, Yokosawa, H, Miura, K, Kobayashi, Y. | | 登録日 | 2002-07-23 | | 公開日 | 2003-03-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Inhibitory Specificity Change of Ovomucoid Third Domain of the Silver Pheasant upon Introduction of an Engineered Cys14-Cys39 Bond
BIOCHEMISTRY, 42, 2003
|
|
8JLB
 | | Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (2.36 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
|
|
8JL9
 | | Cryo-EM structure of the human nucleosome with scFv | | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
|
|
8JLD
 | | Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
|
|
8JLA
 | | Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 | | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
|
|
5X7Y
 | | Crystal Structure of the Dog Lipocalin Allergen Can f 6 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Lipocalin-Can f 6 allergen | | 著者 | Yamamoto, K, Otani, T, Sugiura, K, Nakatsuji, M, Nishimura, S, Inui, T. | | 登録日 | 2017-02-28 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of the dog allergen Can f 6 and structure-based implications of its cross-reactivity with the cat allergen Fel d 4.
Sci Rep, 9, 2019
|
|
7DRU
 | |
6D7G
 | | Structure of 5F3 TCR in complex with HLA-A2/MART-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MART1 PEPTIDE-BETA-2-MICROGLOBULIN-HLA-A*02 CHIMERA, T-CELL RECEPTOR GAMMA VARIABLE 8,T-CELL RECEPTOR GAMMA-2 CHAIN C REGION, ... | | 著者 | Roy, S, Adams, E.J. | | 登録日 | 2018-04-24 | | 公開日 | 2019-01-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Generation and molecular recognition of melanoma-associated antigen-specific human gamma delta T cells.
Sci Immunol, 3, 2018
|
|
6LRA
 | | The complex structure of PHF core domain peptide of tau and antibody's Fab domain. | | 分子名称: | Fab Heavy Chain, Fab Light Chain, VQIINK | | 著者 | Tomohiro, T, Kouki, S, Tomohiro, S, Takahiro, T, Katsushiro, M, Yasuko, I, Katsuhiko, M, Taizo, T, Toshimitsu, I, Koji, T. | | 登録日 | 2020-01-15 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the human tau PHF core domain VQIINK complexed with the Fab domain of monoclonal antibody Tau2r3.
Febs Lett., 2020
|
|
7FGL
 | | The complex structure of PHF core domain peptide of tau, VQIVYK, and antibody's Fab domain. | | 分子名称: | AMMONIUM ION, Fab Heavy Chain, Fab Light Chain, ... | | 著者 | Tsuchida, T, Tsuchiya, T, Miyamoto, K, In, Y, Minoura, K, Taniguchi, T, Ishida, T, Tomoo, K. | | 登録日 | 2021-07-27 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The cross-reaction complex structure with VQIVYK of tau and the antibody's Fab domain.
To Be Published
|
|
7V3D
 | |
7X5O
 | | Crystal structure of E. faecium SHMT in complex with Me-THF and PLP-Gly | | 分子名称: | N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, Serine hydroxymethyltransferase | | 著者 | Hasegawa, K, Hayashi, H. | | 登録日 | 2022-03-05 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors.
Commun Biol, 5, 2022
|
|
7X5N
 | | Crystal structure of E. faecium SHMT in complex with (+)-SHIN-1 and PLP-Ser | | 分子名称: | (4R)-6-azanyl-4-[3-(hydroxymethyl)-5-phenyl-phenyl]-3-methyl-4-propan-2-yl-1H-pyrano[2,3-c]pyrazole-5-carbonitrile, Serine hydroxymethyltransferase, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | | 著者 | Hasegawa, K, Hayashi, H. | | 登録日 | 2022-03-05 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors.
Commun Biol, 5, 2022
|
|
8KB5
 | | Cryo-EM structure of the human nucleosome containing H3.8 | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Hirai, H, Kujirai, T, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-08-03 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.26133 Å) | | 主引用文献 | Cryo-EM and biochemical analyses of the nucleosome containing the human histone H3 variant H3.8.
J.Biochem., 174, 2023
|
|
8HTA
 | |
5MJS
 | |
3A7E
 | | Crystal structure of human COMT complexed with SAM and 3,5-dinitrocatechol | | 分子名称: | 3,5-DINITROCATECHOL, Catechol O-methyltransferase, MAGNESIUM ION, ... | | 著者 | Tsuji, E. | | 登録日 | 2009-09-26 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Hit to Lead: Comprehensive Strategy of de novo Scaffold Generation by FBDD. Part 1: In silico Fragments Linking and Verification of Spatial Proximity using Inter Ligand NOE Approachs
To be Published
|
|
3A7D
 | | Crystal Structures of rat Catechol-O-Methyltransferase complexed with new bi-substrate type inhibitor | | 分子名称: | 5'-deoxy-5'-[4-({[(2,3-dihydroxy-5-nitrophenyl)carbonyl]amino}methyl)-1H-1,2,3-triazol-1-yl]adenosine, Catechol O-methyltransferase, MAGNESIUM ION, ... | | 著者 | Tsuji, E. | | 登録日 | 2009-09-26 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Hit to Lead: Comprehensive Strategy of de novo Scaffold Generation by FBDD. Part 2: Ligand Fishing using Mass Spectrometry by Detection of Ligand-Protein Non-Covalent Complex after Matrix Click Chemistry
To be Published
|
|
