6LRA
The complex structure of PHF core domain peptide of tau and antibody's Fab domain.
Summary for 6LRA
Entry DOI | 10.2210/pdb6lra/pdb |
Descriptor | Fab Heavy Chain, Fab Light Chain, VQIINK, ... (4 entities in total) |
Functional Keywords | tauopathies, tau protein, antibody, alzheimer's disease, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 3 |
Total formula weight | 47534.98 |
Authors | Tomohiro, T.,Kouki, S.,Tomohiro, S.,Takahiro, T.,Katsushiro, M.,Yasuko, I.,Katsuhiko, M.,Taizo, T.,Toshimitsu, I.,Koji, T. (deposition date: 2020-01-15, release date: 2020-08-26, Last modification date: 2023-11-29) |
Primary citation | Tsuchida, T.,Susa, K.,Kibiki, T.,Tsuchiya, T.,Miyamoto, K.,In, Y.,Minoura, K.,Taniguchi, T.,Ishida, T.,Tomoo, K. Crystal structure of the human tau PHF core domain VQIINK complexed with the Fab domain of monoclonal antibody Tau2r3. Febs Lett., 2020 Cited by PubMed: 32282060DOI: 10.1002/1873-3468.13791 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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