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6LRA

The complex structure of PHF core domain peptide of tau and antibody's Fab domain.

Summary for 6LRA
Entry DOI10.2210/pdb6lra/pdb
DescriptorFab Heavy Chain, Fab Light Chain, VQIINK, ... (4 entities in total)
Functional Keywordstauopathies, tau protein, antibody, alzheimer's disease, immune system
Biological sourceMus musculus
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Total number of polymer chains3
Total formula weight47534.98
Authors
Tomohiro, T.,Kouki, S.,Tomohiro, S.,Takahiro, T.,Katsushiro, M.,Yasuko, I.,Katsuhiko, M.,Taizo, T.,Toshimitsu, I.,Koji, T. (deposition date: 2020-01-15, release date: 2020-08-26, Last modification date: 2023-11-29)
Primary citationTsuchida, T.,Susa, K.,Kibiki, T.,Tsuchiya, T.,Miyamoto, K.,In, Y.,Minoura, K.,Taniguchi, T.,Ishida, T.,Tomoo, K.
Crystal structure of the human tau PHF core domain VQIINK complexed with the Fab domain of monoclonal antibody Tau2r3.
Febs Lett., 2020
Cited by
PubMed: 32282060
DOI: 10.1002/1873-3468.13791
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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