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3SL0
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BU of 3sl0 by Molmil
Crystal Structure of P. falciparum arginase complexed with 2-amino-6-borono-2-(difluoromethyl)hexanoic acid
分子名称: 2-(difluoromethyl)-6-(dihydroxyboranyl)-L-norleucine, Arginase, MANGANESE (II) ION
著者Dowling, D.P, Ilies, M, Christianson, D.W.
登録日2011-06-23
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
J.Med.Chem., 54, 2011
3SL1
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BU of 3sl1 by Molmil
Crystal Structure of P. falciparum arginase complexed with 2-amino-6-borono-2-methylhexanoic acid
分子名称: 6-(dihydroxyboranyl)-2-methyl-L-norleucine, Arginase, MANGANESE (II) ION
著者Dowling, D.P, Ilies, M, Christianson, D.W.
登録日2011-06-23
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
J.Med.Chem., 54, 2011
3MMR
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BU of 3mmr by Molmil
Structure of Plasmodium falciparum Arginase in complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase, BETA-MERCAPTOETHANOL, ...
著者Dowling, D.P, Ilies, M, Olszewski, K.L, Portugal, S, Mota, M.M, Llinas, M, Christianson, D.W.
登録日2010-04-20
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection .
Biochemistry, 49, 2010
3MFV
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BU of 3mfv by Molmil
Crystal structure of human arginase I in complex with 2-aminohomohistidine
分子名称: (2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic acid, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2010-04-04
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.
J.Med.Chem., 53, 2010
3GMZ
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BU of 3gmz by Molmil
Crystal of human arginase in complex with L-ornithine. Resolution 1.43 A.
分子名称: Arginase-1, L-ornithine, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2009-03-15
公開日2010-01-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design
J.Med.Chem., 54, 2011
3GN0
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BU of 3gn0 by Molmil
Crystal structure of human arginase I in complex with difluoromethylornithine (DFMO)
分子名称: ALPHA-DIFLUOROMETHYLORNITHINE, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2009-03-15
公開日2010-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design
J.Med.Chem., 54, 2011
3MJL
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BU of 3mjl by Molmil
Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
分子名称: 1H-imidazol-2-amine, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2010-04-13
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human arginase I in complex with 2-aminoimidazole. Resolution 1.90 A.
To be Published
3MFW
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BU of 3mfw by Molmil
Crystal structure of human arginase I in complex with L-2-aminohistidine and sulphate
分子名称: 2-amino-L-histidine, Arginase-1, MANGANESE (II) ION, ...
著者Di Costanzo, L, Christianson, D.W.
登録日2010-04-04
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.
J.Med.Chem., 53, 2010
3SJT
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BU of 3sjt by Molmil
Crystal structure of human arginase I in complex with the inhibitor Me-ABH, Resolution 1.60 A, twinned structure
分子名称: Arginase-1, MANGANESE (II) ION, [(5S)-5-amino-5-carboxyhexyl](trihydroxy)borate
著者Di Costanzo, L, Christianson, D.W.
登録日2011-06-21
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.597 Å)
主引用文献Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
J.Med.Chem., 54, 2011
3SKK
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BU of 3skk by Molmil
Crystal structure of human arginase I in complex with the inhibitor FABH, Resolution 1.70 A, twinned structure
分子名称: Arginase-1, MANGANESE (II) ION, [(5S)-5-amino-5-carboxy-6,6-difluorohexyl](trihydroxy)borate(1-)
著者Thorn, K.J, Di Costanzo, L, Christianson, D.W.
登録日2011-06-22
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Binding of alpha , alpha-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
J.Med.Chem., 54, 2011
5W8B
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BU of 5w8b by Molmil
Carbonic anhydrase II in complex with activating histamine pyridinium derivative
分子名称: 1-[2-(1H-imidazol-5-yl)ethyl]-4-methyl-2,6-di(propan-2-yl)pyridin-1-ium, Carbonic anhydrase 2, GLYCEROL, ...
著者Bhatt, A, Ilies, M, McKenna, R.
登録日2017-06-21
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Crystal Structure of Carbonic Anhydrase II in Complex with an Activating Ligand: Implications in Neuronal Function.
Mol. Neurobiol., 55, 2018
3LP7
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BU of 3lp7 by Molmil
Crystal structure of Human Arginase I in complex with inhibitor N(omega)-hydroxy-L-arginine (NOHA), 2.04A Resolution
分子名称: Arginase-1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE
著者Di Costanzo, L, Christianson, D.W.
登録日2010-02-04
公開日2010-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
3KV2
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BU of 3kv2 by Molmil
HIGH RESOLUTION STRUCTURE OF HUMAN ARGINASE I IN COMPLEX WITH THE STRONG INHIBITOR N(omega)-hydroxy-nor-L-arginine (nor-NOHA)
分子名称: Arginase-1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE
著者Di Costanzo, L, Christianson, D.W.
登録日2009-11-28
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
3LP4
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BU of 3lp4 by Molmil
Crystal structure of human arginase I in complex with L-LYSINE, 1.90A Resolution.
分子名称: Arginase-1, LYSINE, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2010-02-04
公開日2010-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010

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