6QE6
| Structure of M. capricolum TrmK in complex with the natural cofactor product S-adenosyl-homocysteine (SAH) | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Adenine(22)-N(1))-methyltransferase | 著者 | Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C. | 登録日 | 2019-01-04 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites. Rna Biol., 16, 2019
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6QE5
| Structure of E.coli RlmJ in complex with the natural cofactor product S-adenosyl-homocysteine (SAH) | 分子名称: | Ribosomal RNA large subunit methyltransferase J, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C. | 登録日 | 2019-01-04 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites. Rna Biol., 16, 2019
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6QE0
| Structure of E.coli RlmJ in complex with a bisubstrate analogue (BA2) | 分子名称: | (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[2-[[9-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]ethyl]amino]-2-azanyl-butanoic acid, Ribosomal RNA large subunit methyltransferase J | 著者 | Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C. | 登録日 | 2019-01-03 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.394 Å) | 主引用文献 | Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites. Rna Biol., 16, 2019
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6QDX
| Structure of E.coli RlmJ in complex with a bisubstrate analogue (BA4) | 分子名称: | (2~{S})-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[[9-[(2~{S},3~{R},4~{S},5~{S})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]propyl]amino]-2-azanyl-butanoic acid, Ribosomal RNA large subunit methyltransferase J | 著者 | Oerum, S, Catala, M, Atdjian, C, Brachet, F, Ponchon, L, Barraud, P, Iannazzo, L, Droogmans, L, Braud, E, Etheve-Quelquejeu, M, Tisne, C. | 登録日 | 2019-01-03 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites. Rna Biol., 16, 2019
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6FJ1
| Structure of the Ldtfm-avibactam carbamoyl enzyme | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 3,6,9,12,15-PENTAOXAHEPTADECANE, CHLORIDE ION, ... | 著者 | Li de la Sierra Gallay, I, Iannazzo, L, Compain, F, Fonvielle, M, van Tilbeurgh, H, Edoo, Z, Arthur, M, Etheve-Quelquejeu, M, Hugonnet, J. | 登録日 | 2018-01-19 | 公開日 | 2019-01-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Synthesis of Avibactam Derivatives and Activity on beta-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria. Chemistry, 24, 2018
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8PW8
| Crystal structure of the human METTL3-METTL14 in complex with a bisubstrate analogue (BA2) | 分子名称: | (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[2-[[9-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]ethyl]amino]-2-azanyl-butanoic acid, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... | 著者 | Bedi, R.K, Etheve-Quelquejeu, M, Caflisch, A. | 登録日 | 2023-07-19 | 公開日 | 2023-11-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The catalytic mechanism of the RNA methyltransferase METTL3. Elife, 12, 2024
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8PWA
| Crystal structure of the human METTL3-METTL14 in complex with a bisubstrate analogue (BA4) | 分子名称: | (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[[9-[(2~{R},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-7~{H}-purin-6-yl]amino]propyl]amino]-2-azanyl-butanoic acid, ACETATE ION, MAGNESIUM ION, ... | 著者 | Bedi, R.K, Etheve-Quelquejeu, M, Caflisch, A. | 登録日 | 2023-07-19 | 公開日 | 2023-11-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The catalytic mechanism of the RNA methyltransferase METTL3. Elife, 12, 2024
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8PWB
| Crystal structure of the human METTL3-METTL14 in complex with a bisubstrate analogue (BA6) | 分子名称: | (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(7~{H}-purin-6-ylcarbamoyl)amino]-2-azanyl-butanoic acid, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ... | 著者 | Bedi, R.K, Etheve-Quelquejeu, M, Caflisch, A. | 登録日 | 2023-07-19 | 公開日 | 2023-11-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The catalytic mechanism of the RNA methyltransferase METTL3. Elife, 12, 2024
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8PW9
| Crystal structure of the human METTL3-METTL14 in complex with a bisubstrate analogue (BA1) | 分子名称: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[[2-[[9-[(2~{R},3~{R},4~{S},5~{S})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]ethylamino]methyl]oxolane-3,4-diol, ACETATE ION, MAGNESIUM ION, ... | 著者 | Bedi, R.K, Etheve-Quelquejeu, M, Caflisch, A. | 登録日 | 2023-07-19 | 公開日 | 2023-11-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The catalytic mechanism of the RNA methyltransferase METTL3. Elife, 12, 2024
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7P9O
| Structure of E.coli RlmJ in complex with a SAM analogue (CA) | 分子名称: | 5'-{[(3S)-3-amino-3-carboxypropyl]amino}-5'-deoxyadenosine, Ribosomal RNA large subunit methyltransferase J | 著者 | Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C. | 登録日 | 2021-07-27 | 公開日 | 2022-05-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | 主引用文献 | Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase. Nucleic Acids Res., 50, 2022
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7P8Q
| Structure of E.coli RlmJ in complex with an RNA conjugate (GA-SAM) | 分子名称: | 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, RNA conjugate (GA-SAM), Ribosomal RNA large subunit methyltransferase J | 著者 | Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C. | 登録日 | 2021-07-23 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.289 Å) | 主引用文献 | Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase. Nucleic Acids Res., 50, 2022
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7P9I
| Structure of E.coli RlmJ in complex with an RNA conjugate (GAA-SAM) | 分子名称: | 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl)amino}-5'-deoxyadenosine, RNA conjugate (GAA-SAM), Ribosomal RNA large subunit methyltransferase J | 著者 | Meynier, V, Catala, M, Oerum, S, Barraud, P, Tisne, C. | 登録日 | 2021-07-27 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.594 Å) | 主引用文献 | Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase. Nucleic Acids Res., 50, 2022
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7Z6K
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7Z5Z
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7Z6A
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7Z5Y
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