7YHE
 
 | | Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG | | 分子名称: | 2-OXOGLUTARIC ACID, CmnC, FE (III) ION, ... | | 著者 | Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y. | | 登録日 | 2022-07-13 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7YW9
 | | Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG | | 分子名称: | ACETATE ION, CmnC, D-ARGININE, ... | | 著者 | Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y. | | 登録日 | 2022-08-22 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7VGN
 | | Crystal structure of CmnC | | 分子名称: | 2-OXOGLUTARIC ACID, ACETATE ION, CmnC, ... | | 著者 | Huang, S.J, Hsiao, Y.H, Lin, E.C, Lee, Y.C, Zheng, Y.Z, Chang, C.Y. | | 登録日 | 2021-09-17 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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5XU8
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7Y5F
 | | Crystal structure of CmnC in complex with L-homoarginine | | 分子名称: | CmnC, FE (III) ION, L(+)-TARTARIC ACID, ... | | 著者 | Hsiao, Y.H, Huang, S.J, Lin, E.C, Lee, Y.C, Chang, C.Y. | | 登録日 | 2022-06-17 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7Y5I
 | | Crystal structure of CmnC in complex with L-homoarginine | | 分子名称: | ARGININE, CmnC, FE (III) ION, ... | | 著者 | Hsiao, Y.H, Huang, S.J, Lin, E.C, Lee, Y.C, Chang, C.Y. | | 登録日 | 2022-06-17 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7Y5P
 | | Crystal structure of CmnC in complex with L-arginine and alpha-KG | | 分子名称: | 2-OXOGLUTARIC ACID, ARGININE, CmnC, ... | | 著者 | Hsiao, Y.H, Huang, S.J, Lin, E.C, Lee, Y.C, Chang, C.Y. | | 登録日 | 2022-06-17 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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4NDL
 | | Computational design and experimental verification of a symmetric homodimer | | 分子名称: | ENH-c2b, computational designed homodimer | | 著者 | Mou, Y, Huang, P.S, Hsu, F.C, Huang, S.J, Mayo, S.L. | | 登録日 | 2013-10-26 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Computational design and experimental verification of a symmetric protein homodimer.
Proc.Natl.Acad.Sci.USA, 112, 2015
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2MG4
 | | Computational design and experimental verification of a symmetric protein homodimer | | 分子名称: | Computational designed homodimer | | 著者 | Mou, Y, Huang, P.S, Hsu, F.C, Huang, S.J, Mayo, S.L. | | 登録日 | 2013-10-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Computational design and experimental verification of a symmetric protein homodimer.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1RRQ
 | | MutY adenine glycosylase in complex with DNA containing an A:oxoG pair | | 分子名称: | 5'-D(*TP*GP*TP*CP*CP*AP*AP*GP*TP*CP*T)-3', 5'-D(AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', CALCIUM ION, ... | | 著者 | Fromme, J.C, Banerjee, A, Huang, S.J, Verdine, G.L. | | 登録日 | 2003-12-08 | | 公開日 | 2004-02-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Nature, 427, 2004
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1RRS
 | | MutY adenine glycosylase in complex with DNA containing an abasic site | | 分子名称: | 5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*T)-3', CALCIUM ION, ... | | 著者 | Fromme, J.C, Banerjee, A, Huang, S.J, Verdine, G.L. | | 登録日 | 2003-12-08 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Nature, 427, 2004
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1VRL
 | | MutY adenine glycosylase in complex with DNA and soaked adenine free base | | 分子名称: | 5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*T)-3', ADENINE, ... | | 著者 | Fromme, J.C, Banerjee, A, Huang, S.J, Verdine, G.L. | | 登録日 | 2005-03-08 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Nature, 427, 2004
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7V5S
 | | Crystal structure of human bleomycin hydrolase C73A mutant | | 分子名称: | Bleomycin hydrolase, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | | 著者 | Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C. | | 登録日 | 2021-08-18 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
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7V5L
 | | Crystal structure of human bleomycin hydrolase | | 分子名称: | Bleomycin hydrolase | | 著者 | Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C. | | 登録日 | 2021-08-17 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
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7V5T
 | | Crystal structure of human bleomycin hydrolase C73S mutant | | 分子名称: | Bleomycin hydrolase | | 著者 | Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C. | | 登録日 | 2021-08-18 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
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7XF9
 | | Crystal structure of human bleomycin hydrolase H372A mutant | | 分子名称: | Bleomycin hydrolase | | 著者 | Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C. | | 登録日 | 2022-04-01 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
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7VGL
 | | Crystal structure of CmnC | | 分子名称: | ACETATE ION, CmnC | | 著者 | Hsiao, Y.H, Huang, S.J, Lin, E.C, Lee, Y.C, Zheng, Y.Z, Chang, C.Y. | | 登録日 | 2021-09-17 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Front Chem, 10, 2022
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7XDD
 | | Cryo-EM structure of EDS1 and PAD4 | | 分子名称: | Lipase-like PAD4, Protein EDS1 | | 著者 | Huang, S.J, Jia, A.L, Sun, Y, Han, Z.F, Chai, J.J. | | 登録日 | 2022-03-26 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity.
Science, 377, 2022
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7XJP
 | | Cryo-EM structure of EDS1 and SAG101 with ATP-APDR | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5-DIPHOSPHORIBOSE, ISOPROPYL ALCOHOL, ... | | 著者 | Huang, S.J, Jia, A.L, Han, Z.F, Chai, J.J. | | 登録日 | 2022-04-18 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity.
Science, 377, 2022
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5XVE
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6VN7
 | | Cryo-EM structure of an activated VIP1 receptor-G protein complex | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Duan, J, Shen, D.-D, Zhou, X.E, Liu, Q.-F, Zhuang, Y.-W, Zhang, H.-B, Xu, P.-Y, Ma, S.-S, He, X.-H, Melcher, K, Zhang, Y, Xu, H.E, Yi, J. | | 登録日 | 2020-01-29 | | 公開日 | 2020-09-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy.
Nat Commun, 11, 2020
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7Y6J
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7YBR
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7YCQ
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8HY4
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