1WPX
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![BU of 1wpx by Molmil](/molmil-images/mine/1wpx) | Crystal structure of carboxypeptidase Y inhibitor complexed with the cognate proteinase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase Y, Carboxypeptidase Y inhibitor, ... | 著者 | Mima, J, Hayashida, M, Fujii, T, Narita, Y, Hayashi, R, Ueda, M, Hata, Y. | 登録日 | 2004-09-14 | 公開日 | 2005-03-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the carboxypeptidase y inhibitor i(c) in complex with the cognate proteinase reveals a novel mode of the proteinase-protein inhibitor interaction J.Mol.Biol., 346, 2005
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7JW6
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![BU of 7jw6 by Molmil](/molmil-images/mine/7jw6) | Crystal structure of Drosophila Nibbler EXO domain | 分子名称: | Exonuclease mut-7 homolog | 著者 | Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J. | 登録日 | 2020-08-24 | 公開日 | 2021-01-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-function analysis of microRNA 3'-end trimming by Nibbler. Proc.Natl.Acad.Sci.USA, 117, 2020
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7JW2
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![BU of 7jw2 by Molmil](/molmil-images/mine/7jw2) | Crystal structure of Aedes aegypti Nibbler EXO domain | 分子名称: | Exonuclease mut-7 homolog | 著者 | Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J. | 登録日 | 2020-08-24 | 公開日 | 2021-01-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-function analysis of microRNA 3'-end trimming by Nibbler. Proc.Natl.Acad.Sci.USA, 117, 2020
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7JW3
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![BU of 7jw3 by Molmil](/molmil-images/mine/7jw3) | Crystal structure of Aedes aegypti Nibbler NTD domain | 分子名称: | Exonuclease mut-7 homolog | 著者 | Xie, W, Sowemimo, I, Hayashi, R, Wang, J, Brennecke, J, Ameres, S.L, Patel, D.J. | 登録日 | 2020-08-24 | 公開日 | 2021-01-20 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structure-function analysis of microRNA 3'-end trimming by Nibbler. Proc.Natl.Acad.Sci.USA, 117, 2020
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3OQ5
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![BU of 3oq5 by Molmil](/molmil-images/mine/3oq5) | Crystal structure of the 3-MBT domain from human L3MBTL1 in complex with p53K382me1 | 分子名称: | Cellular tumor antigen p53, Lethal(3)malignant brain tumor-like protein | 著者 | Roy, S, West, L.E, Weiner, K.L, Hayashi, R, Shi, X, Appella, E, Gozani, O, Kutateladze, T. | 登録日 | 2010-09-02 | 公開日 | 2010-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5005 Å) | 主引用文献 | The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression. J.Biol.Chem., 285, 2010
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1FS3
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![BU of 1fs3 by Molmil](/molmil-images/mine/1fs3) | |
1EIE
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![BU of 1eie by Molmil](/molmil-images/mine/1eie) | |
1EID
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![BU of 1eid by Molmil](/molmil-images/mine/1eid) | |
1EIC
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![BU of 1eic by Molmil](/molmil-images/mine/1eic) | |
1IZQ
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![BU of 1izq by Molmil](/molmil-images/mine/1izq) | F46V mutant of bovine pancreatic ribonuclease A | 分子名称: | RIBONUCLEASE A | 著者 | Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. | 登録日 | 2002-10-11 | 公開日 | 2003-11-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
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1IZR
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![BU of 1izr by Molmil](/molmil-images/mine/1izr) | F46A mutant of bovine pancreatic ribonuclease A | 分子名称: | RIBONUCLEASE A | 著者 | Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. | 登録日 | 2002-10-11 | 公開日 | 2003-11-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
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1IZP
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![BU of 1izp by Molmil](/molmil-images/mine/1izp) | F46L mutant of bovine pancreatic ribonuclease A | 分子名称: | RIBONUCLEASE A | 著者 | Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. | 登録日 | 2002-10-11 | 公開日 | 2003-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
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7YUZ
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![BU of 7yuz by Molmil](/molmil-images/mine/7yuz) | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP8784 | 分子名称: | AP8784, GUANOSINE-5'-DIPHOSPHATE, IODIDE ION, ... | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | 登録日 | 2022-08-18 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.878 Å) | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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7YV1
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![BU of 7yv1 by Molmil](/molmil-images/mine/7yv1) | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ... | 著者 | Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A. | 登録日 | 2022-08-18 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.454 Å) | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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8JJS
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![BU of 8jjs by Molmil](/molmil-images/mine/8jjs) | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | 登録日 | 2023-05-31 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | 主引用文献 | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor. J.Am.Chem.Soc., 145, 2023
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2MWO
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![BU of 2mwo by Molmil](/molmil-images/mine/2mwo) | |
2MWP
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![BU of 2mwp by Molmil](/molmil-images/mine/2mwp) | |
7Q74
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![BU of 7q74 by Molmil](/molmil-images/mine/7q74) | |
7Q73
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![BU of 7q73 by Molmil](/molmil-images/mine/7q73) | Structure of Pla1 apo | 分子名称: | GLYCEROL, Poly(A) polymerase pla1 | 著者 | Soni, K, Wild, K, Sinning, I. | 登録日 | 2021-11-09 | 公開日 | 2022-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nat Commun, 14, 2023
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7Q72
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![BU of 7q72 by Molmil](/molmil-images/mine/7q72) | Structure of Pla1 in complex with Red1 | 分子名称: | NURS complex subunit red1, Poly(A) polymerase pla1 | 著者 | Soni, K, Wild, K, Sinning, I. | 登録日 | 2021-11-09 | 公開日 | 2022-12-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nat Commun, 14, 2023
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3LH0
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![BU of 3lh0 by Molmil](/molmil-images/mine/3lh0) | |
3LGF
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![BU of 3lgf by Molmil](/molmil-images/mine/3lgf) | |
3LGL
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![BU of 3lgl by Molmil](/molmil-images/mine/3lgl) | |
2K8F
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![BU of 2k8f by Molmil](/molmil-images/mine/2k8f) | Structural Basis for the Regulation of p53 Function by p300 | 分子名称: | Cellular tumor antigen p53, Histone acetyltransferase p300 | 著者 | Bai, Y, Feng, H, Jenkins, L.M, Durell, S.R, Wiodawer, A, Appella, E. | 登録日 | 2008-09-08 | 公開日 | 2009-03-03 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation. Structure, 17, 2009
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