2YAK
 
 | | Structure of death-associated protein Kinase 1 (dapk1) in complex with a ruthenium octasporine ligand (OSV) | | 分子名称: | DEATH-ASSOCIATED PROTEIN KINASE 1, RUTHENIUM OCTASPORINE 4 | | 著者 | Feng, L, Geisselbrecht, Y, Blanck, S, Wilbuer, A, Atilla-Gokcumen, G.E, Filippakopoulos, P, Kraeling, K, Celik, M.A, Harms, K, Maksimoska, J, Marmorstein, R, Frenking, G, Knapp, S, Essen, L.-O, Meggers, E. | | 登録日 | 2011-02-23 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors.
J.Am.Chem.Soc., 133, 2011
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5JQF
 | | Crystal structure of the lasso peptide Sphingopyxin I (SpI) | | 分子名称: | Sphingopyxin I | | 著者 | Fage, C.D, Hegemann, J.D, Harms, K, Bange, G, Marahiel, M.A. | | 登録日 | 2016-05-04 | | 公開日 | 2016-09-14 | | 最終更新日 | 2021-06-16 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase.
Angew. Chem. Int. Ed. Engl., 55, 2016
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4AS0
 | | Cyclometalated Phthalimides as Protein Kinase Inhibitors | | 分子名称: | PHTALIMIDE-RUTHENIUM COMPLEX, SERINE/THREONINE-PROTEIN KINASE PIM-1 | | 著者 | Blanck, S, Geisselbrecht, Y, Middel, S, Mietke, T, Harms, K, Essen, L.-O, Meggers, E. | | 登録日 | 2012-04-27 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Bioactive Cyclometalated Phthalimides: Design, Synthesis and Kinase Inhibition.
Dalton Trans, 41, 2012
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4NAG
 | | Xanthomonins I III are a New Class of Lasso Peptides Featuringa Seven-Membered Macrolactam Ring | | 分子名称: | HEXANE-1,6-DIOL, Xanthomonin I | | 著者 | Hegemann, J.D, Zimmermann, M, Zhu, S, Steuber, H, Harms, K, Xie, X, Marahiel, M.A. | | 登録日 | 2013-10-22 | | 公開日 | 2014-04-30 | | 最終更新日 | 2014-05-21 | | 実験手法 | X-RAY DIFFRACTION (0.81 Å) | | 主引用文献 | Xanthomonins I-III: A New Class of Lasso Peptides with a Seven-Residue Macrolactam Ring.
Angew.Chem.Int.Ed.Engl., 53, 2014
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5D9E
 | | Crystal Structure of the Proline-rich Lasso Peptide Caulosegnin II | | 分子名称: | CHLORIDE ION, Caulosegnin II | | 著者 | Fage, C.D, Hegemann, J.D, Harms, K, Marahiel, M.A. | | 登録日 | 2015-08-18 | | 公開日 | 2016-02-17 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (0.859 Å) | | 主引用文献 | The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II.
Mol Biosyst, 12, 2016
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3PUP
 | | Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1) | | 分子名称: | Glycogen synthase kinase-3 beta, Ruthenium octasporine | | 著者 | Filippakopoulos, P, Kraling, K, Essen, L.O, Meggers, E, Knapp, S. | | 登録日 | 2010-12-06 | | 公開日 | 2010-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors.
J.Am.Chem.Soc., 133, 2011
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2MFV
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7ASS
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5JRL
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5JRK
 | | Crystal Structure of the Sphingopyxin I Lasso Peptide Isopeptidase SpI-IsoP (SeMet-derived) | | 分子名称: | Dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like protein, beta-D-glucopyranose | | 著者 | Fage, C.D, Hegemann, J.D, Bange, G, Marahiel, M.A. | | 登録日 | 2016-05-06 | | 公開日 | 2016-09-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase.
Angew.Chem.Int.Ed.Engl., 55, 2016
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6GEM
 | | FeII-Dependent Halogenase Wi-WelO15 | | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, Oxidoreductase | | 著者 | Srinivasan, V. | | 登録日 | 2018-04-26 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.462 Å) | | 主引用文献 | Directed Evolution of an FeII-Dependent Halogenase for Asymmetric C(sp3)-H Chlorination
ChemRxiv, 2019
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4DAW
 | | Crystal structure of PAK1 kinase domain with the ruthenium phthalimide complex | | 分子名称: | Serine/threonine-protein kinase PAK 1, [1,3-dioxo-6-(pyridin-2-yl-kappaN)-2,3-dihydro-1H-isoindol-5-yl-kappaC~5~][(thioxomethylidene)azanido-kappaN](1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium | | 著者 | Maksimoska, J, Marmorstein, R. | | 登録日 | 2012-01-13 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The art of filling protein pockets efficiently with octahedral metal complexes.
Angew.Chem.Int.Ed.Engl., 51, 2012
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3FXZ
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3FY0
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