3FY0

Crystal structure of PAK1 kinase domain with ruthenium complex DW1

Summary for 3FY0

Entry DOI	10.2210/pdb3fy0/pdb
Related	3FXZ
Descriptor	Serine/threonine-protein kinase PAK 1, Ruthenium pyridocarbazole (3 entities in total)
Functional Keywords	transferase, kinase, atp-binding, phosphorylation, allosteric enzyme, apoptosis, cell junction, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : Q13153
Total number of polymer chains	1
Total formula weight	33863.68
Authors	Maksimoska, J.,Marmorstein, R.,Meggers, E. (deposition date: 2009-01-21, release date: 2009-03-03, Last modification date: 2021-10-20)
Primary citation	Maksimoska, J.,Feng, L.,Harms, K.,Yi, C.,Kissil, J.,Marmorstein, R.,Meggers, E. Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes J.Am.Chem.Soc., 130:15764-15765, 2008 Cited by PubMed: 18973295 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation