6K4N
 
 | | Cryo-EM structure of p300 | | 分子名称: | Histone acetyltransferase p300 | | 著者 | Ghosh, R, Roy, S, Sengupta, J. | | 登録日 | 2019-05-24 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | | 主引用文献 | Tumor Suppressor p53-Mediated Structural Reorganization of the Transcriptional Coactivator p300.
Biochemistry, 58, 2019
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3BCN
 | | Crystal structure of a papain-like cysteine protease Ervatamin-A complexed with irreversible inhibitor E-64 | | 分子名称: | BETA-MERCAPTOETHANOL, Ervatamin-A, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE | | 著者 | Ghosh, R, Chakrabarti, C, Dattagupta, J.K, Biswas, S. | | 登録日 | 2007-11-13 | | 公開日 | 2007-11-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria
Febs J., 275, 2008
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5XZC
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2PNS
 | | 1.9 Angstrom resolution crystal structure of a plant cysteine protease Ervatamin-C refinement with cDNA derived amino acid sequence | | 分子名称: | Ervatamin-C, a papain-like plant cysteine protease, PHOSPHATE ION, ... | | 著者 | Ghosh, R, Guha Thakurta, P, Biswas, S, Chakrabarti, C, Dattagupta, J.K. | | 登録日 | 2007-04-25 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A thermostable cysteine protease precursor from a tropical plant contains an unusual C-terminal propeptide: cDNA cloning, sequence comparison and molecular modeling studies.
Biochem.Biophys.Res.Commun., 362, 2007
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2PRE
 | | Crystal structure of plant cysteine protease Ervatamin-C complexed with irreversible inhibitor E-64 at 2.7 A resolution | | 分子名称: | Ervatamin-C, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, SULFATE ION | | 著者 | Ghosh, R, Chakrabarti, C, Dattagupta, J.K, Biswas, S. | | 登録日 | 2007-05-04 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria.
Febs J., 275, 2008
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2I0W
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7BMK
 | | ATP-Competitive Partial Antagonists-'PAIR's-Rheostatically Modulate IRE1alpha's Kinase Helix-alphaC to Segregate its RNase-Mediated Biological Outputs | | 分子名称: | 1,2-ETHANEDIOL, 2,2,2-tris(fluoranyl)-~{N}-[4-[3-[2-[[(3~{S})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]ethanesulfonamide, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Feldman, H.C, Ghosh, R, Auyeung, V, Mueller, J.L, Vidadala, V.N, Olivier, A, Backes, B.J, Zikherman, J, Papa, F.R, Maly, D.J. | | 登録日 | 2021-01-20 | | 公開日 | 2021-09-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | ATP-competitive partial antagonists of the IRE1 alpha RNase segregate outputs of the UPR.
Nat.Chem.Biol., 17, 2021
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2HRI
 | | A parallel stranded human telomeric quadruplex in complex with the porphyrin TMPyP4 | | 分子名称: | (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3', POTASSIUM ION | | 著者 | Parkinson, G.N, Ghosh, R, Neidle, S. | | 登録日 | 2006-07-20 | | 公開日 | 2007-05-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural basis for binding of porphyrin to human telomeres.
Biochemistry, 46, 2007
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1ORD
 | | CRYSTALLOGRAPHIC STRUCTURE OF A PLP-DEPENDENT ORNITHINE DECARBOXYLASE FROM LACTOBACILLUS 30A TO 3.1 ANGSTROMS RESOLUTION | | 分子名称: | ORNITHINE DECARBOXYLASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Hackert, M.L, Momany, C, Ernst, S, Ghosh, R. | | 登録日 | 1995-02-08 | | 公開日 | 1995-09-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystallographic structure of a PLP-dependent ornithine decarboxylase from Lactobacillus 30a to 3.0 A resolution.
J.Mol.Biol., 252, 1995
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3EM2
 | | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6038 | | 分子名称: | 3,6-Bis[(3-morpholinopropionamido)] acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | | 著者 | Campbell, N.H, Parkinson, G, Neidle, S. | | 登録日 | 2008-09-23 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Selectivity in Ligand Recognition of G-Quadruplex Loops.
Biochemistry, 48, 2009
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3EQW
 | | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6042 in small unit cell | | 分子名称: | 3,6-Bis{3-[(2R)-(2-ethylpiperidino)]propionamido}acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | | 著者 | Campbell, N.H, Parkinson, G, Neidle, S. | | 登録日 | 2008-10-01 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Selectivity in Ligand Recognition of G-Quadruplex Loops.
Biochemistry, 48, 2009
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3ET8
 | | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6054 | | 分子名称: | 3,6-Bis{3-(3-[(3R)-methylpiperidino)]propionamido}acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | | 著者 | Campbell, N.H, Parkinson, G, Neidle, S. | | 登録日 | 2008-10-07 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Selectivity in Ligand Recognition of G-Quadruplex Loops.
Biochemistry, 48, 2009
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3EUM
 | | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6066 | | 分子名称: | 3,6-Bis[3-(azepan-1-yl)propionamido]acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | | 著者 | Campbell, N.H, Parkinson, G, Neidle, S. | | 登録日 | 2008-10-10 | | 公開日 | 2008-10-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Selectivity in Ligand Recognition of G-Quadruplex Loops.
Biochemistry, 48, 2009
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3EUI
 | | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6042 in a large unit cell | | 分子名称: | 3,6-Bis{3-[(2R)-(2-ethylpiperidino)]propionamido}acridine, 3-[(2R)-2-ethylpiperidin-1-yl]-N-[6-({3-[(2S)-2-ethylpiperidin-1-yl]propanoyl}amino)acridin-3-yl]propanamide, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', ... | | 著者 | Campbell, N.H, Parkinson, G, Neidle, S. | | 登録日 | 2008-10-10 | | 公開日 | 2008-12-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Selectivity in Ligand Recognition of G-Quadruplex Loops.
Biochemistry, 48, 2009
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3ERU
 | | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6045 | | 分子名称: | 3,6-Bis{3-[(2R)-2-methylpiperidino)]propionamido}acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | | 著者 | Campbell, N.H, Parkinson, G, Neidle, S. | | 登録日 | 2008-10-03 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Selectivity in Ligand Recognition of G-Quadruplex Loops.
Biochemistry, 48, 2009
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5D1O
 | | Archaeal ATP-dependent RNA ligase - form 1 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA ligase, MAGNESIUM ION, ... | | 著者 | Murakami, K.S. | | 登録日 | 2015-08-04 | | 公開日 | 2016-03-09 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.648 Å) | | 主引用文献 | Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysis.
Nucleic Acids Res., 44, 2016
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5D1P
 | | Archaeal ATP-dependent RNA ligase - form 2 | | 分子名称: | ATP-dependent RNA ligase, MAGNESIUM ION, SULFATE ION | | 著者 | Murakami, K.S. | | 登録日 | 2015-08-04 | | 公開日 | 2016-03-09 | | 最終更新日 | 2016-03-30 | | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | | 主引用文献 | Structural and mutational analysis of archaeal ATP-dependent RNA ligase identifies amino acids required for RNA binding and catalysis.
Nucleic Acids Res., 44, 2016
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3ES0
 | | A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6048 | | 分子名称: | 3,6-Bis[3-(4-methylpiperidino)propionamido]acridine, 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION | | 著者 | Campbell, N.H, Parkinson, G, Neidle, S. | | 登録日 | 2008-10-03 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Selectivity in Ligand Recognition of G-Quadruplex Loops.
Biochemistry, 48, 2009
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1PHO
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1OPF
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1BT9
 | | OMPF PORIN MUTANT D74A | | 分子名称: | PROTEIN (MATRIX PORIN OUTER MEMBRANE PROTEIN F) | | 著者 | Philippsen, A, Schirmer, T. | | 登録日 | 1998-09-01 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Stability of trimeric OmpF porin: the contributions of the latching loop L2.
Biochemistry, 37, 1998
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1MPF
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1GFM
 | | OMPF PORIN (MUTANT D113G) | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MATRIX PORIN OUTER MEMBRANE PROTEIN F | | 著者 | Lou, K.-L, Schirmer, T. | | 登録日 | 1996-05-08 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural and functional characterization of OmpF porin mutants selected for larger pore size. I. Crystallographic analysis.
J.Biol.Chem., 271, 1996
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1GFN
 | | OMPF PORIN DELETION (MUTANT DELTA 109-114) | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MATRIX PORIN OUTER MEMBRANE PROTEIN F | | 著者 | Lou, K.-L, Schirmer, T. | | 登録日 | 1996-05-08 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural and functional characterization of OmpF porin mutants selected for larger pore size. I. Crystallographic analysis.
J.Biol.Chem., 271, 1996
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1GFP
 | | OMPF PORIN (MUTANT R42C) | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MATRIX PORIN OUTER MEMBRANE PROTEIN F | | 著者 | Lou, K.-L, Schirmer, T. | | 登録日 | 1996-05-08 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and functional characterization of OmpF porin mutants selected for larger pore size. I. Crystallographic analysis.
J.Biol.Chem., 271, 1996
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