3EUI

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6042 in a large unit cell

Summary for 3EUI

• Entry DOI: 10.2210/pdb3eui/pdb
• Related: 1JPQ 1JRN 1L1H 3CE5 3EM2 3EQW 3ERU 3ES0 3ET8 3EUM
• Descriptor: 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION, 3-[(2R)-2-ethylpiperidin-1-yl]-N-[6-({3-[(2S)-2-ethylpiperidin-1-yl]propanoyl}amino)acridin-3-yl]propanamide, ... (6 entities in total)
• Functional Keywords: quadruplex, oxytricha nova, bsu-6042, bsu6042, anti-parallel, bimolecular, macromolecule, dna, g-quadruplex
• Total number of polymer chains: 4
• Total formula weight: 16824.45

Authors

Campbell, N.H.,Parkinson, G.,Neidle, S. (deposition date: 2008-10-10, release date: 2008-12-02, Last modification date: 2023-09-06)

• Primary citation: Campbell, N.H.,Patel, M.,Tofa, A.B.,Ghosh, R.,Parkinson, G.N.,Neidle, S.; Selectivity in Ligand Recognition of G-Quadruplex Loops.; Biochemistry, 48:1675-1680, 2009; PubMed: 19173611; DOI: 10.1021/bi802233v

Experimental method

X-RAY DIFFRACTION (2.2 Å)