3EM2

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine BSU-6038

Summary for 3EM2

• Entry DOI: 10.2210/pdb3em2/pdb
• Related: 1JPQ 1JRN 1L1H 3CE5 3EQW 3ERU 3ES0 3ET8
• Descriptor: 5'-D(*DGP*DGP*DGP*DGP*DTP*DTP*DTP*DTP*DGP*DGP*DGP*DG)-3', POTASSIUM ION, 3,6-Bis[(3-morpholinopropionamido)] acridine, ... (4 entities in total)
• Functional Keywords: quadruplex, oxytricha nova, bsu-6038, bsu6038, anti-parallel, bimolecular, macromolecule, g-quadruplex, dna
• Total number of polymer chains: 2
• Total formula weight: 8258.89

Authors

Campbell, N.H.,Parkinson, G.,Neidle, S. (deposition date: 2008-09-23, release date: 2008-10-14, Last modification date: 2023-09-06)

• Primary citation: Campbell, N.H.,Patel, M.,Tofa, A.B.,Ghosh, R.,Parkinson, G.N.,Neidle, S.; Selectivity in Ligand Recognition of G-Quadruplex Loops.; Biochemistry, 48:1675-1680, 2009; PubMed: 19173611; DOI: 10.1021/bi802233v

Experimental method

X-RAY DIFFRACTION (2.3 Å)