2PRE
Crystal structure of plant cysteine protease Ervatamin-C complexed with irreversible inhibitor E-64 at 2.7 A resolution
Summary for 2PRE
Entry DOI | 10.2210/pdb2pre/pdb |
Related | 1O0E 2PNS |
Descriptor | Ervatamin-C, SULFATE ION, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, ... (4 entities in total) |
Functional Keywords | protease-inhibitor complex, papain-like fold, plant cysteine protease, ervatamin, hydrolase |
Biological source | Tabernaemontana divaricata |
Total number of polymer chains | 2 |
Total formula weight | 47285.90 |
Authors | Ghosh, R.,Chakrabarti, C.,Dattagupta, J.K.,Biswas, S. (deposition date: 2007-05-04, release date: 2008-01-22, Last modification date: 2023-08-30) |
Primary citation | Ghosh, R.,Chakraborty, S.,Chakrabarti, C.,Dattagupta, J.K.,Biswas, S. Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria. Febs J., 275:421-434, 2008 Cited by PubMed: 18167146DOI: 10.1111/j.1742-4658.2007.06211.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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