2HRI

A parallel stranded human telomeric quadruplex in complex with the porphyrin TMPyP4

Summary for 2HRI

• Entry DOI: 10.2210/pdb2hri/pdb
• Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3', POTASSIUM ION, (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, ... (4 entities in total)
• Functional Keywords: quadruplex, dna, propeller, dimeric, human telomere parallel stranded, ligand, complex
• Total number of polymer chains: 2
• Total formula weight: 8413.48

Authors

Parkinson, G.N.,Ghosh, R.,Neidle, S. (deposition date: 2006-07-20, release date: 2007-05-08, Last modification date: 2023-08-30)

• Primary citation: Parkinson, G.N.,Ghosh, R.,Neidle, S.; Structural basis for binding of porphyrin to human telomeres.; Biochemistry, 46:2390-2397, 2007; PubMed: 17274602; DOI: 10.1021/bi062244n

Experimental method

X-RAY DIFFRACTION (2.09 Å)