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6QZV
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BU of 6qzv by Molmil
DPP9 bound to a dipeptide (MP) from the N-terminus of BRCA2
分子名称: Dipeptidyl peptidase 9, MET-PRO
著者Ross, B, Geiss-Friedlander, R, Huber, R.
登録日2019-03-12
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair
Biorxiv, 2020
6QZW
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BU of 6qzw by Molmil
DPP8 bound to a dipeptide (MP) from the N-terminus of BRCA2
分子名称: Dipeptidyl peptidase 8, MET-PRO, SODIUM ION
著者Ross, B, Geiss-Friedlander, R, Huber, R.
登録日2019-03-12
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair
Biorxiv, 2020
7OZ7
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BU of 7oz7 by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, L84
分子名称: Dipeptidyl peptidase 8, trimethylamine oxide, ~{N}-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]-2-ethyl-2-methanoyl-butanamide
著者Ross, B, Huber, R.
登録日2021-06-26
公開日2021-07-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 61, 2022
7OR4
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BU of 7or4 by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B142
分子名称: Dipeptidyl peptidase 8, methyl 3-[4-[(4-bromophenyl)methyl]piperazin-1-yl]carbonyl-5-[(2-ethyl-2-methanoyl-butanoyl)amino]benzoate, trimethylamine oxide
著者Ross, B, Huber, R.
登録日2021-06-04
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 61, 2022
7NVQ
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BU of 7nvq by Molmil
Aerosol-soaked human cdk2 crystals with Staurosporine
分子名称: 1,2-ETHANEDIOL, Cyclin-dependent kinase 2, STAUROSPORINE
著者Ross, B, Huber, R.
登録日2021-03-15
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Aerosol-based ligand soaking of reservoir-free protein crystals.
J.Appl.Crystallogr., 54, 2021
7ZXS
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BU of 7zxs by Molmil
Crystal structure of DPP9 in complex with a 4-oxo-b-lactam based inhibitor, A295
分子名称: 1,2-ETHANEDIOL, 2-ethyl-2-methanoyl-~{N}-[3-[[4-(quinolin-8-ylmethyl)piperazin-1-yl]methyl]phenyl]butanamide, DI(HYDROXYETHYL)ETHER, ...
著者Ross, B, Huber, R.
登録日2022-05-22
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 61, 2022
6TRW
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BU of 6trw by Molmil
Crystal structure of DPP8 in complex with the EIL peptide (SLRFLFEGQRIADNH)
分子名称: Dipeptidyl peptidase 8, SER-LEU-ARG-PHE-LEU-PHE-GLU-GLY-GLN-ARG, SODIUM ION
著者Ross, B, Huber, R.
登録日2019-12-19
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Aerosol-based ligand soaking of reservoir-free protein crystals.
J.Appl.Crystallogr., 54, 2021
6TRX
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BU of 6trx by Molmil
Crystal structure of DPP8 in complex with 1G244
分子名称: (2~{S})-2-azanyl-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione, Dipeptidyl peptidase 8, PHOSPHATE ION, ...
著者Ross, B.H, Huber, R.
登録日2019-12-19
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Aerosol-based ligand soaking of reservoir-free protein crystals.
J.Appl.Crystallogr., 54, 2021
7A3G
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BU of 7a3g by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, 91
分子名称: 1-[3-(7,8-dihydro-5~{H}-[1,3]dioxolo[4,5-g]isoquinolin-6-ylmethyl)phenyl]-3,3-diethyl-azetidine-2,4-dione, CHLORIDE ION, Dipeptidyl peptidase 8, ...
著者Ross, B.H, Huber, R.
登録日2020-08-18
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
7A3J
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BU of 7a3j by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, A272
分子名称: 2-ethyl-2-methanoyl-~{N}-[3-[[4-(naphthalen-1-ylmethyl)piperazin-1-yl]methyl]phenyl]butanamide, CHLORIDE ION, Dipeptidyl peptidase 8, ...
著者Ross, B.H, Huber, R.
登録日2020-08-18
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
7A3L
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BU of 7a3l by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, A241
分子名称: 2-ethyl-2-methanoyl-~{N}-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]butanamide, CHLORIDE ION, Dipeptidyl peptidase 8, ...
著者Ross, B.H, Huber, R.
登録日2020-08-18
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
7AYR
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BU of 7ayr by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B115
分子名称: Dipeptidyl peptidase 8, PHOSPHATE ION, trimethylamine oxide, ...
著者Ross, B.H, Huber, R.
登録日2020-11-13
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
7AYQ
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BU of 7ayq by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B114
分子名称: Dipeptidyl peptidase 8, GLYCEROL, PHOSPHATE ION, ...
著者Ross, B, Huber, R.
登録日2020-11-13
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew.Chem.Int.Ed.Engl., 2022
7A3F
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BU of 7a3f by Molmil
Crystal structure of apo DPP9
分子名称: Dipeptidyl peptidase 9, GLYCEROL, PHOSPHATE ION
著者Ross, B.H, Huber, R.
登録日2020-08-18
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery and Development of 4-Oxo-beta-Lactams as Novel Inhibitors of Dipeptidyl Peptidases 8 and 9
To Be Published
7A3I
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BU of 7a3i by Molmil
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, LMC375
分子名称: CHLORIDE ION, Dipeptidyl peptidase 8, SODIUM ION, ...
著者Ross, B.H, Huber, R.
登録日2020-08-18
公開日2021-06-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery and Development of 4-Oxo-beta-Lactams as Novel Inhibitors of Dipeptidyl Peptidases 8 and 9
To Be Published
7A3K
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BU of 7a3k by Molmil
Crystal structure of DPP8 in complex with a b-lactam based inhibitor, A296.1
分子名称: 1-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]azetidin-2-one, CHLORIDE ION, Dipeptidyl peptidase 8, ...
著者Ross, B.H, Huber, R.
登録日2020-08-18
公開日2021-07-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Discovery and Development of 4-Oxo-beta-Lactams as Novel Inhibitors of Dipeptidyl Peptidases 8 and 9
To Be Published
6EOP
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BU of 6eop by Molmil
DPP8 - SLRFLYEG, space group 20
分子名称: CALCIUM ION, CITRATE ANION, Dipeptidyl peptidase 8, ...
著者Ross, B.R, Huber, R.
登録日2017-10-10
公開日2018-02-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EOO
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BU of 6eoo by Molmil
DPP8 - Apo, space group 20
分子名称: Dipeptidyl peptidase 8
著者Ross, B.R, Huber, R.
登録日2017-10-10
公開日2018-02-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EOR
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BU of 6eor by Molmil
DPP9 - 1G244
分子名称: (2~{S})-2-azanyl-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione, Dipeptidyl peptidase 9
著者Ross, B.R, Huber, R.
登録日2017-10-10
公開日2018-02-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EOS
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BU of 6eos by Molmil
DPP8 - Apo, space group 19
分子名称: Dipeptidyl peptidase 8
著者Ross, B.R, Huber, R.
登録日2017-10-10
公開日2018-02-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EOQ
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BU of 6eoq by Molmil
DPP9 - Apo
分子名称: Dipeptidyl peptidase 9
著者Ross, B.R, Huber, R.
登録日2017-10-10
公開日2018-02-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EOT
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BU of 6eot by Molmil
DPP8 - SLRFLYEG, space group 19
分子名称: Dipeptidyl peptidase 8, SER-LEU-ARG-PHE-LEU-TYR-GLU-GLY
著者Ross, B.R, Huber, R.
登録日2017-10-10
公開日2018-02-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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件を2024-10-09に公開中

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