5WOZ
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5WOX
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5WOT
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5WOY
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6E5C
| Solution NMR structure of a de novo designed double-stranded beta-helix | 分子名称: | De novo beta protein | 著者 | Marcos, E, Chidyausiku, T.M, McShan, A, Evangelidis, T, Nerli, S, Sgourakis, N, Tripsianes, K, Baker, D. | 登録日 | 2018-07-19 | 公開日 | 2018-11-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | De novo design of a non-local beta-sheet protein with high stability and accuracy. Nat. Struct. Mol. Biol., 25, 2018
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7OX6
| Solution structure of human interleukin-9 | 分子名称: | Interleukin-9 | 著者 | Savvides, S.N, Tripsianes, K, De Vos, T, Papageorgiou, A, Evangelidis, T. | 登録日 | 2021-06-22 | 公開日 | 2022-12-28 | 最終更新日 | 2023-01-11 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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6YEU
| Second EH domain of AtEH1/Pan1 | 分子名称: | CALCIUM ION, Calcium-binding EF hand family protein | 著者 | Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K. | 登録日 | 2020-03-25 | 公開日 | 2021-03-31 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding. Nat Commun, 12, 2021
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6YET
| Second EH domain of AtEH1/Pan1 | 分子名称: | CALCIUM ION, Calcium-binding EF hand family protein | 著者 | Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K. | 登録日 | 2020-03-25 | 公開日 | 2021-03-31 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding. Nat Commun, 12, 2021
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7SKN
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7SKP
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7SKO
| De novo synthetic protein DIG8-CC (orthogonal space group) | 分子名称: | De novo synthetic protein DIG8-CC, MAGNESIUM ION | 著者 | Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X. | 登録日 | 2021-10-21 | 公開日 | 2022-10-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | De novo design of immunoglobulin-like domains Nat Commun, 13, 2022
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7OX5
| hIL-9:hIL-9Ra complex | 分子名称: | Interleukin-9, Interleukin-9 receptor, SULFATE ION | 著者 | De Vos, T, Savvides, S.N. | 登録日 | 2021-06-22 | 公開日 | 2022-12-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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7OX4
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7OX3
| Fab 6D3: hIL-9 complex | 分子名称: | Heavy chain (Fab 6D3), Interleukin-9, Light chain (Fab 6D3), ... | 著者 | De Vos, T, Savvides, S.N. | 登録日 | 2021-06-22 | 公開日 | 2022-12-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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7OX2
| Fab 6E2: hIL-9 complex | 分子名称: | Heavy chain (Fab 6E2), Interleukin-9, Light chain (Fab 6E2), ... | 著者 | De Vos, T, Savvides, S.N. | 登録日 | 2021-06-22 | 公開日 | 2022-12-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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7OX1
| Fab 7D6: hIL-9 complex | 分子名称: | Heavy chain (Fab 7D6), Interleukin-9, Light chain (Fab 7D6) | 著者 | De Vos, T, Savvides, S.N. | 登録日 | 2021-06-22 | 公開日 | 2022-12-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9) Biorxiv, 2022
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6Y99
| hSTING mutant R232K in complex with 2',3'-cGAMP | 分子名称: | Stimulator of interferon genes protein, cGAMP | 著者 | Boura, E, Smola, M. | 登録日 | 2020-03-06 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.984 Å) | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
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6YDB
| Human wtSTING in complex with 2',2'-difluoro-3',3'-c-di-GMP | 分子名称: | 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{R})-17-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-8-yl]-1~{H}-purin-6-one, Stimulator of interferon protein | 著者 | Boura, E, Smola, M. | 登録日 | 2020-03-20 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
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6YDZ
| Human wtSTING in complex with 3',3'-cGAMP | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon protein | 著者 | Boura, E, Smola, M. | 登録日 | 2020-03-23 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
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6YEA
| Human wtSTING in complex with 2',2'-difluoro-3',3'-cGAMP | 分子名称: | 2',2'-difluoro-3',3'-cGAMP, Stimulator of interferon protein | 著者 | Boura, E, Smola, M. | 登録日 | 2020-03-24 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
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6YIG
| Crystal structure of the N-terminal EF-hand domain of Arabidopsis thaliana AtEH1/Pan1 | 分子名称: | CALCIUM ION, Calcium-binding EF hand family protein, SODIUM ION | 著者 | Yperman, K, Merceron, R, De Munck, S, Bloch, Y, Savvides, S.N, Pleskot, R, Van Damme, D. | 登録日 | 2020-04-01 | 公開日 | 2021-04-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding. Nat Commun, 12, 2021
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6Z15
| Human wtSTING in complex with 3',3'-c-di-AMP | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of interferon protein | 著者 | Boura, E, Smola, M. | 登録日 | 2020-05-12 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
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6Z0Z
| Human wtSTING in complex with 3',3'-c-(2'FdAMP-2'FdAMP) | 分子名称: | 2'-fluoro-,3',3'-c-di-AMP, Stimulator of interferon protein | 著者 | Boura, E, Smola, M. | 登録日 | 2020-05-11 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
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