3O4L
| Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BSLF2/BMLF1 protein, Beta-2-microglobulin, ... | 著者 | Miles, J.J, Bulek, A.M, Cole, D.K, Gostick, E, Schauenburg, J.A, Dolton, G, Venturi, V, Davenport, M.P, Tan, M.P, Burrows, S.R, Wooldridge, L, Price, D.A, Rizkallah, P.J, Sewell, A.K. | 登録日 | 2010-07-27 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. Plos Pathog., 6, 2010
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7ZUC
| Human Major Histocompatibility Complex A2 allele presenting LLLGIGILV | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-LEU-LEU-GLY-ILE-GLY-ILE-LEU-VAL, ... | 著者 | Rizkallah, P.J, Wall, A, Sewell, A.K, Fuller, A. | 登録日 | 2022-05-12 | 公開日 | 2023-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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7P3D
| MHC I A02 Allele presenting YLQPRTFLL | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | 登録日 | 2021-07-07 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope. Cell, 185, 2022
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7P3E
| MHC I A02 Allele presenting YLQLRTFLL | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, IODIDE ION, ... | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | 登録日 | 2021-07-07 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope. Cell, 185, 2022
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7PBE
| Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Human T-cell Receptor YLQ36, ... | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | 登録日 | 2021-08-02 | 公開日 | 2022-04-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope. Cell, 185, 2022
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7Q9B
| MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | 登録日 | 2021-11-12 | 公開日 | 2023-02-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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7Q99
| MHC Class I A02 Allele presenting NLSALGIFST, in complex with Mel5 TCR | 分子名称: | 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | 登録日 | 2021-11-12 | 公開日 | 2023-02-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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7Q98
| MHC Class I A02 Allele presenting NLSALGIFST | 分子名称: | 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Sewell, A.K. | 登録日 | 2021-11-12 | 公開日 | 2023-02-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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7Q9A
| MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR | 分子名称: | Beta-2-microglobulin, GLYCEROL, Human Mel5 T Cell Receptor, ... | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | 登録日 | 2021-11-12 | 公開日 | 2023-02-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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4I4W
| Peptide length determines the outcome of T cell receptor/peptide-MHCI engagement | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Wooldridge, L, Cole, D.K. | 登録日 | 2012-11-28 | 公開日 | 2013-01-02 | 最終更新日 | 2015-11-25 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood, 121, 2013
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6G3J
| MHC A02 Allele presenting MTSAIGILVP | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Rizkallah, P.J, Sewell, A.K. | 登録日 | 2018-03-26 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Peptide Super-Agonist Enhances T-Cell Responses to Melanoma. Front Immunol, 10, 2019
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6HBY
| HLA class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope | 分子名称: | 1,2-ETHANEDIOL, ARRPPLAELAALNLSGSRL 5T4 tumour epitope, HLA class II histocompatibility antigen, ... | 著者 | MacLachlan, B, Rizkallah, P.J, Sewell, A.K, Cole, D.K, Godkin, A.J. | 登録日 | 2018-08-13 | 公開日 | 2019-08-14 | 最終更新日 | 2020-01-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. J.Biol.Chem., 294, 2019
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6G3K
| MHC A02 Allele presenting MTSAIGILPV | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Rizkallah, P.J, Sewell, A.K. | 登録日 | 2018-03-26 | 公開日 | 2019-09-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Peptide Super-Agonist Enhances T-Cell Responses to Melanoma. Front Immunol, 10, 2019
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6QZD
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6QZA
| HLA-DR1 with GMF Influenza PB1 Peptide | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | 著者 | Greenshields-Watson, A, Rizkallah, P.J. | 登録日 | 2019-03-11 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features. Cell Rep, 32, 2020
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5EU5
| HLA Class I antigen | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | 登録日 | 2015-11-18 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen. J.Biol.Chem., 291, 2016
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5EU6
| HLA Class I antigen | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | 登録日 | 2015-11-18 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen. J.Biol.Chem., 291, 2016
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5EU4
| HLA Class I antigen | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | 登録日 | 2015-11-18 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen. J.Biol.Chem., 291, 2016
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5EU3
| HLA Class I antigen | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K. | 登録日 | 2015-11-18 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen. J.Biol.Chem., 291, 2016
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6R0E
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3UTS
| 1E6-A*0201-ALWGPDPAAA Complex, Monoclinic | 分子名称: | 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M. | 登録日 | 2011-11-26 | 公開日 | 2012-01-25 | 最終更新日 | 2012-03-07 | 実験手法 | X-RAY DIFFRACTION (2.712 Å) | 主引用文献 | Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat.Immunol., 13, 2012
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6QZC
| HLA-DR1 with the QAR Peptide | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Greenshields-Watson, A, Rizkallah, P.J. | 登録日 | 2019-03-11 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features. Cell Rep, 32, 2020
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3UTT
| 1E6-A*0201-ALWGPDPAAA Complex, Triclinic | 分子名称: | 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M, Rossjohn, J, Gras, S. | 登録日 | 2011-11-26 | 公開日 | 2012-01-25 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat.Immunol., 13, 2012
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3UTP
| 1E6 TCR specific for HLA-A*0201-ALWGPDPAAA | 分子名称: | 1E6 TCR alpha chain, 1E6 TCR beta chain, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M. | 登録日 | 2011-11-26 | 公開日 | 2012-01-25 | 最終更新日 | 2012-03-07 | 実験手法 | X-RAY DIFFRACTION (2.574 Å) | 主引用文献 | Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat.Immunol., 13, 2012
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3UTQ
| Human HLA-A*0201-ALWGPDPAAA | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M. | 登録日 | 2011-11-26 | 公開日 | 2012-01-25 | 最終更新日 | 2012-03-07 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat.Immunol., 13, 2012
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