5EU4

HLA Class I antigen

Summary for 5EU4

• Entry DOI: 10.2210/pdb5eu4/pdb
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Peptide antigen YLAPGPVTA, ... (7 entities in total)
• Functional Keywords: immuno, hla-a02, 1e6-tcr, cross-reactivity, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01892; Secreted : P61769
• Total number of polymer chains: 6
• Total formula weight: 90574.32

Authors

Rizkallah, P.J.,Bianchi, V.,Cole, D.K.,Sewell, A.K. (deposition date: 2015-11-18, release date: 2016-03-02, Last modification date: 2024-01-10)

• Primary citation: Bianchi, V.,Bulek, A.,Fuller, A.,Lloyd, A.,Attaf, M.,Rizkallah, P.J.,Dolton, G.,Sewell, A.K.,Cole, D.K.; A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.; J.Biol.Chem., 291:8951-8959, 2016; PubMed: 26917722; DOI: 10.1074/jbc.M115.707414

Experimental method

X-RAY DIFFRACTION (2.12 Å)