Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1HRH
DownloadVisualize
BU of 1hrh by Molmil
CRYSTAL STRUCTURE OF THE RIBONUCLEASE H DOMAIN OF HIV-1 REVERSE TRANSCRIPTASE
分子名称: RIBONUCLEASE H
著者Davies /II, J.F, Matthews, D.A.
登録日1991-03-06
公開日1992-01-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase.
Science, 252, 1991
1DR5
DownloadVisualize
BU of 1dr5 by Molmil
CRYSTAL STRUCTURES OF ORGANOMERCURIAL-ACTIVATED CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXES
分子名称: CALCIUM ION, DIHYDROFOLATE REDUCTASE, MERCURY (II) ION, ...
著者Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J.
登録日1992-03-14
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes
To be Published
1DR4
DownloadVisualize
BU of 1dr4 by Molmil
CRYSTAL STRUCTURES OF ORGANOMERCURIAL-ACTIVATED CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXES
分子名称: 7,8-DIHYDROBIOPTERIN, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ...
著者Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J.
登録日1992-03-14
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes
To be Published
1DR3
DownloadVisualize
BU of 1dr3 by Molmil
2.3 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH THIONADP+ AND BIOPTERIN
分子名称: 7,8-DIHYDROBIOPTERIN, 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ...
著者Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J.
登録日1992-03-14
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes.
Biochemistry, 32, 1993
1DR2
DownloadVisualize
BU of 1dr2 by Molmil
2.3 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH THIONADP+ AND BIOPTERIN
分子名称: 7-THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, DIHYDROFOLATE REDUCTASE
著者Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J.
登録日1992-03-14
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of chicken liver dihydrofolate reductase: binary thioNADP+ and ternary thioNADP+.biopterin complexes.
Biochemistry, 32, 1993
1DR1
DownloadVisualize
BU of 1dr1 by Molmil
2.2 ANGSTROMS CRYSTAL STRUCTURE OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADP+ AND BIOPTERIN
分子名称: 7,8-DIHYDROBIOPTERIN, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ...
著者Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J.
登録日1992-03-14
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin.
Biochemistry, 31, 1992
1DR6
DownloadVisualize
BU of 1dr6 by Molmil
CRYSTAL STRUCTURES OF ORGANOMERCURIAL-ACTIVATED CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXES
分子名称: 7,8-DIHYDROBIOPTERIN, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ...
著者Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J.
登録日1992-03-14
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes
To be Published
1DR7
DownloadVisualize
BU of 1dr7 by Molmil
CRYSTAL STRUCTURES OF ORGANOMERCURIAL-ACTIVATED CHICKEN LIVER DIHYDROFOLATE REDUCTASE COMPLEXES
分子名称: CALCIUM ION, DIHYDROFOLATE REDUCTASE, MERCURIBENZOIC ACID, ...
著者Mctigue, M.A, Davies /II, J.F, Kaufman, B.T, Xuong, N.-H, Kraut, J.
登録日1992-03-14
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Organomercurial-Activated Chicken Liver Dihydrofolate Reductase Complexes
To be Published
2DHF
DownloadVisualize
BU of 2dhf by Molmil
CRYSTAL STRUCTURES OF RECOMBINANT HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 5-DEAZOFOLATE
分子名称: 5-DEAZAFOLIC ACID, DIHYDROFOLATE REDUCTASE
著者Davies /II, J.F, Kraut, J.
登録日1989-10-25
公開日1990-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate.
Biochemistry, 29, 1990
1DHF
DownloadVisualize
BU of 1dhf by Molmil
CRYSTAL STRUCTURES OF RECOMBINANT HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 5-DEAZOFOLATE
分子名称: DIHYDROFOLATE REDUCTASE, FOLIC ACID
著者Davies /II, J.F, Kraut, J.
登録日1989-10-25
公開日1990-07-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate.
Biochemistry, 29, 1990
8DFR
DownloadVisualize
BU of 8dfr by Molmil
REFINED CRYSTAL STRUCTURES OF CHICKEN LIVER DIHYDROFOLATE REDUCTASE. 3 ANGSTROMS APO-ENZYME AND 1.7 ANGSTROMS NADPH HOLO-ENZYME COMPLEX
分子名称: CALCIUM ION, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Matthews, D.A, Oatley, S.J, Burridge, J, Kaufman, B.T, Xuong, N.-H, Kraut, J.
登録日1989-05-30
公開日1989-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Refined Crystal Structures of Chicken Liver Dihydrofolate Reductase. 3 Angstroms Apo-Enzyme and 1.7 Angstroms Nadph Holo-Enzyme Complex
To be Published
1OHR
DownloadVisualize
BU of 1ohr by Molmil
VIRACEPT (R) (NELFINAVIR MESYLATE, AG1343): A POTENT ORALLY BIOAVAILABLE INHIBITOR OF HIV-1 PROTEASE
分子名称: 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE, ASPARTYLPROTEASE
著者Davies II, J.F.
登録日1997-09-27
公開日1998-12-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease.
J.Med.Chem., 40, 1997
1RPL
DownloadVisualize
BU of 1rpl by Molmil
2.3 ANGSTROMS CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF DNA POLYMERASE BETA
分子名称: DNA POLYMERASE BETA
著者Davies II, J.F, Almassy, R.J.
登録日1994-10-25
公開日1995-01-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献2.3 A crystal structure of the catalytic domain of DNA polymerase beta.
Cell(Cambridge,Mass.), 76, 1994
2DRC
DownloadVisualize
BU of 2drc by Molmil
INVESTIGATION OF THE FUNCTIONAL ROLE OF TRYPTOPHAN-22 IN ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE BY SITE-DIRECTED MUTAGENESIS
分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
著者Brown, K.A, Kraut, J.
登録日1992-06-10
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Biochemistry, 30, 1991
3K98
DownloadVisualize
BU of 3k98 by Molmil
HSP90 N-terminal domain in complex with (1R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide
分子名称: (1R)-2-[(5-chloro-2,4-dihydroxyphenyl)carbonyl]-N-ethyl-2,3-dihydro-1H-isoindole-1-carboxamide, Heat shock protein HSP 90-alpha, PHOSPHATE ION
著者Gajiwala, K.S, Davies II, J.F.
登録日2009-10-15
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone.
J.Med.Chem., 53, 2010
3K99
DownloadVisualize
BU of 3k99 by Molmil
HSP90 N-terminal domain in complex with 4-(1,3-dihydro-2H-isoindol-2-ylcarbonyl)benzene-1,3-diol
分子名称: 4-(1,3-dihydro-2H-isoindol-2-ylcarbonyl)benzene-1,3-diol, Heat shock protein HSP 90-alpha
著者Gajiwala, K.S, Davies II, J.F.
登録日2009-10-15
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone.
J.Med.Chem., 53, 2010
1DYJ
DownloadVisualize
BU of 1dyj by Molmil
ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS
分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Reyes, V.M, Kraut, J.
登録日1994-10-26
公開日1995-06-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
Biochemistry, 34, 1995
1DYH
DownloadVisualize
BU of 1dyh by Molmil
ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS
分子名称: 5-DEAZAFOLIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Reyes, V.M, Kraut, J.
登録日1994-10-26
公開日1995-06-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
Biochemistry, 34, 1995
1DYI
DownloadVisualize
BU of 1dyi by Molmil
ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS
分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
著者Reyes, V.M, Kraut, J.
登録日1994-10-26
公開日1995-06-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
Biochemistry, 34, 1995
1DRA
DownloadVisualize
BU of 1dra by Molmil
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
著者Oatley, S.J, Kraut, J.
登録日1991-11-06
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30, 1991
1DRB
DownloadVisualize
BU of 1drb by Molmil
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
著者David, C, Kraut, J.
登録日1991-11-06
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30, 1991
3DRC
DownloadVisualize
BU of 3drc by Molmil
INVESTIGATION OF THE FUNCTIONAL ROLE OF TRYPTOPHAN-22 IN ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE BY SITE-DIRECTED MUTAGENESIS
分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
著者Oatley, S.J, Kraut, J.
登録日1992-09-22
公開日1994-01-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Biochemistry, 30, 1991
1JOL
DownloadVisualize
BU of 1jol by Molmil
THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE
分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
著者Lee, H, Reyes, V.M, Kraut, J.
登録日1996-02-25
公開日1996-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4.
Biochemistry, 35, 1996
1JOM
DownloadVisualize
BU of 1jom by Molmil
THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX BETWEEN FOLINIC ACID (LEUCOVORIN) AND E. COLI DIHYDROFOLATE REDUCTASE
分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
著者Reyes, V.M, Lee, H, Kraut, J.
登録日1996-02-25
公開日1996-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4.
Biochemistry, 35, 1996
1RDH
DownloadVisualize
BU of 1rdh by Molmil
CRYSTALLOGRAPHIC ANALYSES OF AN ACTIVE HIV-1 RIBONUCLEASE H DOMAIN SHOW STRUCTURAL FEATURES THAT DISTINGUISH IT FROM THE INACTIVE FORM
分子名称: HIV-1 REVERSE TRANSCRIPTASE (RIBONUCLEASE H DOMAIN)
著者Finzel, B.C, Chattopadhyay, D, Einspahr, H.M.
登録日1993-03-05
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic analyses of an active HIV-1 ribonuclease H domain show structural features that distinguish it from the inactive form.
Acta Crystallogr.,Sect.D, 49, 1993

227111

件を2024-11-06に公開中

PDB statisticsPDBj update infoContact PDBjnumon