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1AL5
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A-TRACT RNA DODECAMER, NMR, 12 STRUCTURES
分子名称: RNA (5'-R(*CP*GP*CP*AP*AP*AP*UP*UP*UP*GP*CP*G)-3')
著者Conte, M.R, Conn, G.L, Brown, T, Lane, A.N.
登録日1997-06-11
公開日1997-12-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Conformational properties and thermodynamics of the RNA duplex r(CGCAAAUUUGCG)2: comparison with the DNA analogue d(CGCAAATTTGCG)2.
Nucleic Acids Res., 25, 1997
1BAX
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BU of 1bax by Molmil
MASON-PFIZER MONKEY VIRUS MATRIX PROTEIN, NMR, AVERAGE STRUCTURE
分子名称: M-PMV MATRIX PROTEIN
著者Conte, M.R, Klikova, M, Hunter, E, Ruml, T, Matthews, S.
登録日1998-04-20
公開日1998-06-17
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献The three-dimensional solution structure of the matrix protein from the type D retrovirus, the Mason-Pfizer monkey virus, and implications for the morphology of retroviral assembly.
EMBO J., 16, 1997
1QM9
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BU of 1qm9 by Molmil
NMR, REPRESENTATIVE STRUCTURE
分子名称: POLYPYRIMIDINE TRACT-BINDING PROTEIN
著者Conte, M.R, Grune, T, Curry, S, Matthews, S.
登録日1999-09-22
公開日2000-07-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of Tandem RNA Recognition Motifs from Polypyrimidine Tract Binding Protein Reveals Novel Features of the Rrm Fold
Embo J., 19, 2000
2G2K
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BU of 2g2k by Molmil
NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5 (eIF5)
分子名称: Eukaryotic translation initiation factor 5
著者Conte, M.R, Kelly, G, Babon, J, Sanfelice, D, Smerdon, S.J, Proud, C.G.
登録日2006-02-16
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors
Biochemistry, 45, 2006
1SAA
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BU of 1saa by Molmil
ATF-2 RECOGNITION SITE, NMR, 10 STRUCTURES
分子名称: DNA (5'-D(*CP*AP*TP*GP*TP*GP*AP*CP*GP*TP*CP*AP*CP*AP*TP*G)-3')
著者Conte, M.R, Lane, A.N, Bloomberg, G.
登録日1997-08-19
公開日1997-11-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the ATF-2 recognition site and its interaction with the ATF-2 peptide.
Nucleic Acids Res., 25, 1997
6I9B
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BU of 6i9b by Molmil
NMR structure of the La module from human LARP4A
分子名称: La-related protein 4
著者Conte, M.R, Martino, L, Atkinson, R.A, Kelly, G, Cruz-Gallardo, I, De Tito, S, Trotta, R.
登録日2018-11-22
公開日2019-03-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Nucleic Acids Res., 47, 2019
2L8K
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BU of 2l8k by Molmil
NMR Structure of the Arterivirus nonstructural protein 7 alpha (nsp7 alpha)
分子名称: Non-structural protein 7
著者Conte, M.R, Gaudin, C, Manolaridis, I, Tucker, P.W, Kelly, G.
登録日2011-01-19
公開日2011-07-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and Genetic Analysis of the Arterivirus Nonstructural Protein 7{alpha}.
J.Virol., 85, 2011
6I5G
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BU of 6i5g by Molmil
X-ray structure of human soluble Epoxide Hydrolase C-terminal Domain (hsEH CTD)in complex with 15d-PGJ2
分子名称: (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid, 1,2-ETHANEDIOL, Bifunctional epoxide hydrolase 2
著者Abis, G, Kopec, J, Yue, W.W, Conte, M.R.
登録日2018-11-13
公開日2019-05-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献15-deoxy-Delta12,14-Prostaglandin J2inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism.
Commun Biol, 2, 2019
6I5E
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BU of 6i5e by Molmil
X-ray structure of apo human soluble Epoxide Hydrolase C-terminal Domain (hsEH CTD)
分子名称: Bifunctional epoxide hydrolase 2
著者Abis, G, Kopec, J, Yue, W.W, Conte, M.R.
登録日2018-11-13
公開日2019-05-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献15-deoxy-Delta12,14-Prostaglandin J2inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism.
Commun Biol, 2, 2019
2VOP
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BU of 2vop by Molmil
Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUUUU
分子名称: 5'-R(*AP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN, SULFATE ION
著者Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S.
登録日2008-02-19
公開日2008-05-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein.
Structure, 16, 2008
2VOD
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BU of 2vod by Molmil
Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUAUUUU
分子名称: 5'-R(*AP*UP*AP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN
著者Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S.
登録日2008-02-15
公開日2008-05-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein.
Structure, 16, 2008
2VON
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BU of 2von by Molmil
Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUAAUUU
分子名称: 5'-R(*AP*UP*AP*AP*UP*UP*UP)-3', LUPUS LA PROTEIN
著者Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S.
登録日2008-02-19
公開日2008-05-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein.
Structure, 16, 2008
2VOO
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BU of 2voo by Molmil
Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer UUUUUUUU
分子名称: 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN
著者Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S.
登録日2008-02-19
公開日2008-05-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein.
Structure, 16, 2008
2MTG
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BU of 2mtg by Molmil
Solution structure of the RRM1 of human LARP6
分子名称: La-related protein 6
著者Martino, L, Atkinson, A.R, Kelly, G, Conte, M.R.
登録日2014-08-18
公開日2014-12-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Nucleic Acids Res., 43, 2015
2MTF
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BU of 2mtf by Molmil
Solution structure of the La motif of human LARP6
分子名称: La-related protein 6
著者Martino, L, Salisbury, N.JH, Atkinson, A.R, Kelly, G, Conte, M.R.
登録日2014-08-18
公開日2014-12-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Nucleic Acids Res., 43, 2015
1S7A
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BU of 1s7a by Molmil
NMR structure of the La motif of human La protein
分子名称: Lupus La protein
著者Alfano, C, Sanfelice, D, Babon, J, Kelly, G, Jacks, A, Curry, S, Conte, M.R.
登録日2004-01-29
公開日2004-04-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein.
Nat.Struct.Mol.Biol., 11, 2004
1S79
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BU of 1s79 by Molmil
Solution structure of the central RRM of human La protein
分子名称: Lupus La protein
著者Alfano, C, Sanfelice, D, Babon, J, Kelly, G, Jacks, A, Curry, S, Conte, M.R.
登録日2004-01-29
公開日2004-04-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein.
Nat.Struct.Mol.Biol., 11, 2004
2KFW
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BU of 2kfw by Molmil
Solution structure of full-length SlyD from E.coli
分子名称: FKBP-type peptidyl-prolyl cis-trans isomerase slyD
著者Martino, L, He, Y, Hands-Taylor, K.L, Valentine, E.R, Kelly, G, Giancola, C, Conte, M.R.
登録日2009-02-28
公開日2009-09-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The interaction of the Escherichia coli protein SlyD with nickel ions illuminates the mechanism of regulation of its peptidyl-prolyl isomerase activity.
Febs J., 276, 2009
1OWX
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BU of 1owx by Molmil
Solution structure of the C-terminal RRM of human La (La225-334)
分子名称: Lupus La protein
著者Jacks, A, Babon, J, Kelly, G, Manolaridis, I, Cary, P.D, Curry, S, Conte, M.R.
登録日2003-03-31
公開日2003-07-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element
Structure, 11, 2003
1SJR
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BU of 1sjr by Molmil
NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
分子名称: Polypyrimidine tract-binding protein 1
著者Simpson, P.J, Monie, T.P, Szendroi, A, Davydova, N, Tyzack, J.K, Conte, M.R, Read, C.M, Cary, P.D, Svergun, D.I, Konarev, P.V, Petoukhov, M.V, Curry, S, Matthews, S.J.
登録日2004-03-04
公開日2004-09-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and RNA Interactions of the N-Terminal RRM Domains of PTB
Structure, 12, 2004
1SJQ
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BU of 1sjq by Molmil
NMR Structure of RRM1 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
分子名称: Polypyrimidine tract-binding protein 1
著者Simpson, P.J, Monie, T.P, Szendroi, A, Davydova, N, Tyzack, J.K, Conte, M.R, Read, C.M, Cary, P.D, Svergun, D.I, Konarev, P.V, Petoukhov, M.V, Curry, S, Matthews, S.J.
登録日2004-03-04
公開日2004-09-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and RNA Interactions of the N-Terminal RRM Domains of PTB
Structure, 12, 2004
5O90
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BU of 5o90 by Molmil
Crystal structure of a P38alpha T185G mutant in complex with TAB1 peptide.
分子名称: 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, Mitogen-activated protein kinase 14, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
著者Nichols, C.E, De Nicola, G.F, Thapa, D.
登録日2017-06-15
公開日2018-01-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献TAB1-Induced Autoactivation of p38 alpha Mitogen-Activated Protein Kinase Is Crucially Dependent on Threonine 185.
Mol. Cell. Biol., 38, 2018
6GJ4
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Tubulin-6j complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-(quinolin-5-yl)naphtho[2,3-b]pyrrolo[1,2-d][1,4]oxazepin-4-yl acetate, CALCIUM ION, ...
著者Brindisi, M, Ulivieri, C, Alfano, G, Gemma, S, Balaguer, F.d.A, Khan, T, Grillo, A, Chemi, G, Menchon, G, Prota, A.E, Olieric, N, Agell, D.L, Barasoain, I, Diaz, J.F, Nebbioso, A, Conte, M.R, Lopresti, L, Magnano, S, Amet, R, Kinsella, P, Zisterer, D.M, Ibrahim, O, O'Sullivan, J, Morbidelli, L, Spaccapelo, R, Baldari, C, Butini, S, Novellino, E, Campiani, G, Altucci, L, Steinmetz, M.O, Brogi, S.
登録日2018-05-16
公開日2018-12-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents.
Eur J Med Chem, 162, 2018
3PKN
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BU of 3pkn by Molmil
Crystal structure of MLLE domain of poly(A) binding protein in complex with PAM2 motif of La-related protein 4 (LARP4)
分子名称: IODIDE ION, La-related protein 4, Polyadenylate-binding protein 1, ...
著者Xie, J, Kozlov, G, Gehring, K.
登録日2010-11-11
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability.
Mol.Cell.Biol., 31, 2011
4LOO
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Structural basis of autoactivation of p38 alpha induced by TAB1 (Monoclinic crystal form)
分子名称: 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, Mitogen-activated protein kinase 14, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
著者Chaikuad, A, DeNicola, G.F, Krojer, T, Allerston, C.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Marber, M.S, Knapp, S, Structural Genomics Consortium (SGC)
登録日2013-07-13
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1.
Nat.Struct.Mol.Biol., 20, 2013

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