2VOP

Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUUUU

Summary for 2VOP

• Entry DOI: 10.2210/pdb2vop/pdb
• Related: 1OWX 1S79 1S7A 1YTY 1ZH5 2VOD 2VON 2VOO
• Descriptor: LUPUS LA PROTEIN, 5'-R(*AP*UP*UP*UP*UP)-3', SULFATE ION (3 entities in total)
• Functional Keywords: rna-binding protein, rna recognition motif, systemic lupus erythematosus, phosphoprotein, rna maturation, rna binding protein, nucleus, la motif, rna-binding, polymorphism
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus (Probable): P05455
• Total number of polymer chains: 2
• Total formula weight: 24230.85

Authors

Kotik-Kogan, O.,Valentine, E.R.,Sanfelice, D.,Conte, M.R.,Curry, S. (deposition date: 2008-02-19, release date: 2008-05-06, Last modification date: 2023-12-13)

• Primary citation: Kotik-Kogan, O.,Valentine, E.R.,Sanfelice, D.,Conte, M.R.,Curry, S.; Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein.; Structure, 16:852-, 2008; PubMed: 18547518; DOI: 10.1016/J.STR.2008.02.021

Experimental method

X-RAY DIFFRACTION (2.8 Å)