Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6RY9
DownloadVisualize
BU of 6ry9 by Molmil
Winter flounder 1a-1 in SDS micelles
分子名称: Pleurocidin-like prepropolypeptide
著者Clarke, M, Mason, A.J.
登録日2019-06-10
公開日2020-07-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Winter flounder 1a-1 in SDS micelles
To Be Published
6S2D
DownloadVisualize
BU of 6s2d by Molmil
Winter flounder 1 in SDS micelles
分子名称: Pleurocidin-like prepropolypeptide
著者Clarke, M, Mason, A.J.
登録日2019-06-20
公開日2020-07-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Winter flounder 1 in SDS micelles
To Be Published
6RZC
DownloadVisualize
BU of 6rzc by Molmil
Winter flounder 4 in SDS micelles
分子名称: Pleurocidin-like peptide WF4
著者Mason, A.J, Clarke, M.
登録日2019-06-13
公開日2020-07-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Winter flounder 4 in SDS micelles
To Be Published
8C65
DownloadVisualize
BU of 8c65 by Molmil
Crystal structure of cutinase AdCut from Acidovorax delafieldii (PBS depolymerase)
分子名称: PBS(A) depolymerase
著者Zahn, M, Clark, M.
登録日2023-01-11
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.491 Å)
主引用文献Predictions of the substrate specificities of the plastic-degrading enzymes IsPETase and AdCut
To Be Published
6RYQ
DownloadVisualize
BU of 6ryq by Molmil
Winter flounder 1a in SDS micelles
分子名称: Pleurocidin-like prepropolypeptide
著者Mason, A.J, Clarke, M.
登録日2019-06-11
公開日2020-07-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Winter flounder 1a in SDS micelles
To Be Published
7ZF1
DownloadVisualize
BU of 7zf1 by Molmil
Structure of ubiquitinated FANCI in complex with FANCD2 and double-stranded DNA
分子名称: DNA (61-MER), Fanconi anemia group D2 protein, Fanconi anemia group I protein, ...
著者Lemonidis, K, Rennie, M.L, Arkinson, C, Streetley, J, Clarke, M, Chaugule, V.K, Walden, H.
登録日2022-03-31
公開日2022-11-16
最終更新日2023-02-08
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination.
Embo J., 42, 2023
6EHM
DownloadVisualize
BU of 6ehm by Molmil
Model of the Ebola virus nucleocapsid subunit from recombinant virus-like particles
分子名称: Membrane-associated protein VP24, Nucleoprotein
著者Wan, W, Kolesnikova, L, Clarke, M, Koehler, A, Noda, T, Becker, S, Briggs, J.A.G.
登録日2017-09-13
公開日2017-11-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structure and assembly of the Ebola virus nucleocapsid.
Nature, 551, 2017
6EHL
DownloadVisualize
BU of 6ehl by Molmil
Model of the Ebola virus nucleoprotein in recombinant nucleocapsid-like assemblies
分子名称: Nucleoprotein
著者Wan, W, Kolesnikova, L, Clarke, M, Koehler, A, Noda, T, Becker, S, Briggs, J.A.G.
登録日2017-09-13
公開日2017-11-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Structure and assembly of the Ebola virus nucleocapsid.
Nature, 551, 2017
6RZ1
DownloadVisualize
BU of 6rz1 by Molmil
Winter flounder 3 in SDS micelles
分子名称: Pleurocidin-like peptide WF3
著者Mason, A.J, Clarke, M.
登録日2019-06-12
公開日2020-07-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of winter flounder AMP 3
To Be Published
7ABK
DownloadVisualize
BU of 7abk by Molmil
Helical structure of PspA
分子名称: Chloroplast membrane-associated 30 kD protein
著者Junglas, B, Huber, S.T, Mann, D, Heidler, T, Clarke, M, Schneider, D, Sachse, C.
登録日2020-09-07
公開日2021-08-04
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献PspA adopts an ESCRT-III-like fold and remodels bacterial membranes.
Cell, 184, 2021
8CXC
DownloadVisualize
BU of 8cxc by Molmil
Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics
分子名称: 3F2 Antibody heavy chain, 3F2 Antibody light chain, Mesothelin, ...
著者Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E.
登録日2022-05-20
公開日2023-06-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (4.31 Å)
主引用文献Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics
Front. Drug Discov., 3, 2023
8CZ8
DownloadVisualize
BU of 8cz8 by Molmil
Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics
分子名称: Mesothelin, cleaved form, SULFATE ION, ...
著者Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E.
登録日2022-05-24
公開日2023-06-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics
Front. Drug Discov., 3, 2023
8CYH
DownloadVisualize
BU of 8cyh by Molmil
Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, A12 antibody heavy chain, A12 antibody light chain, ...
著者Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E.
登録日2022-05-23
公開日2023-06-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics
Front. Drug Discov., 3, 2023
1DYL
DownloadVisualize
BU of 1dyl by Molmil
9 ANGSTROM RESOLUTION CRYO-EM RECONSTRUCTION STRUCTURE OF SEMLIKI FOREST VIRUS (SFV) AND FITTING OF THE CAPSID PROTEIN STRUCTURE IN THE EM DENSITY
分子名称: NUCLEOCAPSID PROTEIN
著者Mancini, E.J, Clarke, M, Gowen, B.E, Rutten, T, Fuller, S.D.
登録日2000-02-02
公開日2000-08-18
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Cryo-Electron Microscopy Reveals the Functional Organization of an Enveloped Virus, Semliki Forest Virus.
Mol.Cell, 5, 2000
2N2H
DownloadVisualize
BU of 2n2h by Molmil
Solution structure of Sds3 in complex with Sin3A
分子名称: Paired amphipathic helix protein Sin3a, Sin3 histone deacetylase corepressor complex component SDS3
著者Clark, M, Radhakrishnan, I.
登録日2015-05-08
公開日2015-07-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural insights into the assembly of the histone deacetylase-associated Sin3L/Rpd3L corepressor complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
5OTF
DownloadVisualize
BU of 5otf by Molmil
MRCK beta in complex with BDP-00009066
分子名称: (6~{S})-8-(3-pyrimidin-4-yl-1~{H}-pyrrolo[2,3-b]pyridin-4-yl)-1,8-diazaspiro[5.5]undecane, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Schuettelkopf, A.W.
登録日2017-08-21
公開日2018-02-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer.
Cancer Res., 78, 2018
7SNC
DownloadVisualize
BU of 7snc by Molmil
Pacifastin related protease inhibitors
分子名称: Protease inhibitor
著者Gewe, M.M, Strong, R.K.
登録日2021-10-27
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
7SND
DownloadVisualize
BU of 7snd by Molmil
Pacifastin related protease inhibitors
分子名称: GLYCEROL, PHOSPHATE ION, Pacifastin-related peptide
著者Gewe, M.M, Strong, R.K.
登録日2021-10-27
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
6OBA
DownloadVisualize
BU of 6oba by Molmil
The beta2 adrenergic receptor bound to a negative allosteric modulator
分子名称: (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, 6-bromo-N~2~-phenylquinazoline-2,4-diamine, Beta-2 adrenergic receptor,Lysozyme,Beta-2 adrenergic receptor, ...
著者Liu, X, Stobel, A, Kaindl, J, Dengler, D, ClarK, M, Mahoney, J, Korczynska, M, Matt, R.A, Hubner, H, Xu, X, Stanek, M, Hirata, K, Shoichet, B, Sunahara, R, Gmeiner, R, Kobilka, B.K.
登録日2019-03-20
公開日2020-03-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献An allosteric modulator binds to a conformational hub in the beta2adrenergic receptor.
Nat.Chem.Biol., 16, 2020
7SJQ
DownloadVisualize
BU of 7sjq by Molmil
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T-cell engager
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cystine-dense peptide, GLYCEROL, ...
著者Rupert, P.B, Strong, R.
登録日2021-10-18
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
7AW0
DownloadVisualize
BU of 7aw0 by Molmil
MerTK kinase domain in complex with purine inhibitor
分子名称: 2-(cyclopentyloxy)-9-(2,6-difluorobenzyl)-N-methyl-9H-purin-6-amine, Tyrosine-protein kinase Mer
著者Schimpl, M, Nissink, J.W.M, Blackett, C, Clarke, M, Disch, J, Goldberg, K, Guilinger, J, Hennessy, E.J, Jetson, R, Ginkunja, D, Hardaker, E, Keefe, A, McCoull, W, McMurray, L, Collingwood, O, Overman, R, Pflug, A, Preston, M, Rawlins, P, Rivers, E, Smith, P, Underwood, E, Truman, C, Warwicker, J, Winter, J, Woodcock, S, Zhang, Y.
登録日2020-11-06
公開日2021-03-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.893 Å)
主引用文献Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy.
J.Med.Chem., 64, 2021
7XKA
DownloadVisualize
BU of 7xka by Molmil
Structure of human beta2 adrenergic receptor bound to constrained epinephrine
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Camelid Antibody Fragment, Endolysin,Beta-2 adrenergic receptor, ...
著者Xu, X, Shonberg, J, Kaindl, J, Clark, M, Stobel, A, Maul, L, Mayer, D, Hubner, H, Venkatakrishnan, A, Dror, R, Kobilka, B.K, Sunahara, R, Liu, X, Gmeiner, P.
登録日2022-04-19
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Constrained catecholamines gain beta 2 AR selectivity through allosteric effects on pocket dynamics.
Nat Commun, 14, 2023
7XK9
DownloadVisualize
BU of 7xk9 by Molmil
Structure of human beta2 adrenergic receptor bound to constrained isoproterenol
分子名称: (5R,6R)-6-(propan-2-ylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Camelid Antibody Fragment, Endolysin,Beta-2 adrenergic receptor, ...
著者Xu, X, Shonberg, J, Kaindl, J, Clark, M, Stobel, A, Maul, L, Mayer, D, Hubner, H, Venkatakrishnan, A, Dror, R, Kobilka, B.K, Sunahara, R, Liu, X, Gmeiner, P.
登録日2022-04-19
公開日2023-04-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Constrained catecholamines gain beta 2 AR selectivity through allosteric effects on pocket dynamics.
Nat Commun, 14, 2023
5OTE
DownloadVisualize
BU of 5ote by Molmil
MRCK beta in complex with BDP-00008900
分子名称: 1,2-ETHANEDIOL, 2-[4-[(6~{S})-1,8-diazaspiro[5.5]undecan-8-yl]-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]-1,3-thiazole, CHLORIDE ION, ...
著者Schuettelkopf, A.W.
登録日2017-08-21
公開日2018-02-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer.
Cancer Res., 78, 2018
6RSG
DownloadVisualize
BU of 6rsg by Molmil
NMR structure of pleurocidin VA in SDS micelles
分子名称: Pleurocidin
著者Manzo, G, Mason, A.J.
登録日2019-05-21
公開日2020-12-09
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A pleurocidin analogue with greater conformational flexibility, enhanced antimicrobial potency and in vivo therapeutic efficacy.
Commun Biol, 3, 2020

 

123>

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon