6VAL
| |
6VAI
| |
6VAM
| |
6VAK
| |
6WHU
| GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 1 | 分子名称: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WHW
| GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 1 | 分子名称: | (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WHY
| GluN1b-GluN2B NMDA receptor in complex with GluN1 antagonist L689,560, class 1 | 分子名称: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
9ARF
| Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in nonactive1 conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2024-02-23 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Molecular mechanism of ligand gating and opening of NMDA receptor. Nature, 632, 2024
|
|
9ARH
| |
9BIB
| Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in open-channel conformation, C1 symmetry | 分子名称: | GLUTAMIC ACID, GLYCINE, Glutamate receptor, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2024-04-23 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.81 Å) | 主引用文献 | Molecular mechanism of ligand gating and opening of NMDA receptor. Nature, 632, 2024
|
|
9ARG
| |
9ARI
| |
9ARE
| Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in open-channel conformation | 分子名称: | GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2024-02-23 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Molecular mechanism of ligand gating and opening of NMDA receptor. Nature, 632, 2024
|
|
5D18
| Crystal structure of Mycobacterium tuberculosis Rv0302, form I | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ISOPROPYL ALCOHOL, SODIUM ION, ... | 著者 | Chou, T.-H, Delmar, J, Su, C.-C, Yu, E. | 登録日 | 2015-08-04 | 公開日 | 2015-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302. Protein Sci., 2015
|
|
5D19
| |
8E97
| PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E94
| PYD-106-bound Human GluN1a-GluN2C NMDA receptor in intact conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E93
| D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in splayed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E92
| D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in intact conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E99
| Human GluN1a-GluN2A-GluN2C triheteromeric NMDA receptor in complex with Nb-4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E98
| D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in nanodisc - intact conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
7SAB
| Phencyclidine-bound GluN1a-GluN2B NMDA receptors | 分子名称: | 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2021-09-22 | 公開日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
|
|
7SAD
| Memantine-bound GluN1a-GluN2B NMDA receptors | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2021-09-22 | 公開日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
|
|
7SAA
| |
7SAC
| |