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3ZIF
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BU of 3zif by Molmil
Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly
分子名称: HEXON PROTEIN, PENTON PROTEIN, PIX, ...
著者Cheng, L, Huang, X, Li, X, Xiong, W, Sun, W, Yang, C, Zhang, K, Wang, Y, Liu, H, Ji, G, Sun, F, Zheng, C, Zhu, P.
登録日2013-01-09
公開日2014-01-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates
Virology, 450, 2014
3IZ3
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BU of 3iz3 by Molmil
CryoEM structure of cytoplasmic polyhedrosis virus
分子名称: Structural protein VP1, Structural protein VP3, Viral structural protein 5
著者Cheng, L, Sun, J, Zhang, K, Mou, Z, Huang, X, Ji, G, Sun, F, Zhang, J, Zhu, P.
登録日2010-09-14
公開日2011-03-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping.
Proc.Natl.Acad.Sci.USA, 108, 2011
5Z4D
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BU of 5z4d by Molmil
Structure of Tailor in complex with AGUU RNA
分子名称: RNA (5'-R(*AP*GP*UP*U)-3'), Terminal uridylyltransferase Tailor
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-11
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
5Z4M
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BU of 5z4m by Molmil
Structure of TailorD343A with bound UTP and Mg
分子名称: MAGNESIUM ION, Terminal uridylyltransferase Tailor, URIDINE 5'-TRIPHOSPHATE
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-11
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
5Z4C
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BU of 5z4c by Molmil
Crystal structure of Tailor
分子名称: Terminal uridylyltransferase Tailor
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-10
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
5Z4J
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BU of 5z4j by Molmil
Structure of Tailor in complex with U4 RNA
分子名称: RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-11
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
5Z4A
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BU of 5z4a by Molmil
Structure of Tailor in complex with AGU RNA
分子名称: RNA (5'-R(*AP*GP*U)-3'), Terminal uridylyltransferase Tailor
著者Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q.
登録日2018-01-10
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.637 Å)
主引用文献Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
7ECA
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BU of 7eca by Molmil
Crystal structure of the Keap1 complex with a peptide base on ETGE motif.
分子名称: Kelch-like ECH-associated protein 1, LEU-ASP-GLU-GLU-THR-GLY-GLU-PHE-LEU-PRO, SULFATE ION
著者Cheng, L, Wang, C.
登録日2021-03-11
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.00006342 Å)
主引用文献New insights into the mechanism of Keap1-Nrf2 interaction based on cancer-associated mutations.
Life Sci, 282, 2021
4CIK
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BU of 4cik by Molmil
plasminogen kringle 1 in complex with inhibitor
分子名称: 5-[(2R,4S)-2-(phenylmethyl)piperidin-4-yl]-1,2-oxazol-3-one, PLASMINOGEN
著者Xue, Y, Johansson, C, Cheng, L, Pettersen, D, Gustafsson, D.
登録日2013-12-10
公開日2014-06-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Discovery of the Fibrinolysis Inhibitor Azd6564, Acting Via Interference of a Protein-Protein Interaction.
Acs Med.Chem.Lett., 5, 2014
7BR3
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BU of 7br3 by Molmil
Crystal structure of the protein 1
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R)-2,3-dihydroxypropyl dodecanoate, 4-[[(1R)-2-[5-(2-fluoranyl-3-methoxy-phenyl)-3-[[2-fluoranyl-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-bis(oxidanylidene)pyrimidin-1-yl]-1-phenyl-ethyl]amino]butanoic acid, ...
著者Cheng, L, Shao, Z.
登録日2020-03-26
公開日2020-10-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode.
Nat Commun, 11, 2020
8JZ7
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BU of 8jz7 by Molmil
Cryo-EM structure of MK-6892-bound HCAR2 in complex with Gi protein
分子名称: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H.
登録日2023-07-04
公開日2023-10-04
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2.
Signal Transduct Target Ther, 8, 2023
3JA5
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BU of 3ja5 by Molmil
Genome and RdRp structure within the capsid of no-transcribing cypovirus
分子名称: RNA-dependent RNA polymerase
著者Liu, H, Cheng, L.
登録日2015-04-21
公開日2015-10-28
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Cryo-EM shows the polymerase structures and a nonspooled genome within a dsRNA virus.
Science, 349, 2015
4U6V
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BU of 4u6v by Molmil
Mechanisms of Neutralization of a Human Anti-Alpha Toxin Antibody
分子名称: Alpha-hemolysin, Fab, antigen binding fragment, ...
著者Oganesyan, V.Y, Peng, L, Damschroder, M.M, Cheng, L, Sadowska, A, Tkaczyk, C, Sellman, B, Wu, H, Dall'Acqua, W.F.
登録日2014-07-29
公開日2014-09-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Mechanisms of Neutralization of a Human Anti-alpha-toxin Antibody.
J.Biol.Chem., 289, 2014
4RN5
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BU of 4rn5 by Molmil
B1 domain of human Neuropilin-1 with acetate ion in a ligand-binding site
分子名称: ACETATE ION, GLYCEROL, Neuropilin-1, ...
著者Allerston, C.K, Yelland, T.S, Jarvis, A, Jenkins, K, Winfield, N, Cheng, L, Jia, H, Zachary, I, Selwood, D.L, Djordjevic, S.
登録日2014-10-23
公開日2015-10-28
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Conserved water molecules in a ligand-binding site of neuropilin-1
To be Published
4WVR
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BU of 4wvr by Molmil
Crystal structure of Dscam1 Ig7 domain, isoform 5
分子名称: Down syndrome cell adhesion molecule, isoform AK
著者Chen, Q, Yu, Y, Li, S, Cheng, L.
登録日2014-11-07
公開日2015-11-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.948 Å)
主引用文献Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4X83
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BU of 4x83 by Molmil
Crystal structure of Dscam1 isoform 7.44, N-terminal four Ig domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Chen, Q, Yu, Y, Li, S.A, Cheng, L.
登録日2014-12-10
公開日2015-12-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4X9B
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BU of 4x9b by Molmil
Crystal structure of Dscam1 isoform 4.44, N-terminal four Ig domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule, isoform 4.44, ...
著者Chen, Q, Yu, Y, Li, S.A, Cheng, L.
登録日2014-12-11
公開日2015-12-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4X9F
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BU of 4x9f by Molmil
Crystal structure of Dscam1 isoform 6.9, N-terminal four Ig domains
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Down Syndrome Cell Adhesion Molecule isoform 6.9, GLYCEROL, ...
著者Chen, Q, Yu, Y, Li, S.A, Cheng, L.
登録日2014-12-11
公開日2015-12-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4X9G
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BU of 4x9g by Molmil
Crystal structure of Dscam1 isoform 6.44, N-terminal four Ig domains
分子名称: Down Syndrome Cell Adhesion Molecule isoform 6.44, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Chen, Q, Yu, Y, Li, S.A, Cheng, L.
登録日2014-12-11
公開日2015-12-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.403 Å)
主引用文献Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4X5L
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BU of 4x5l by Molmil
Crystal structure of Dscam1 Ig7 domain, isoform 9
分子名称: Down syndrome cell adhesion molecule, isoform AM, SODIUM ION
著者Chen, Q, Yu, Y, Li, S.A, Cheng, L.
登録日2014-12-05
公開日2015-12-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.374 Å)
主引用文献Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4XB7
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BU of 4xb7 by Molmil
Crystal structure of Dscam1 isoform 4.4, N-terminal four Ig domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule, isoform 4.4, ...
著者Chen, Q, Yu, Y, Li, S.A, Cheng, L.
登録日2014-12-16
公開日2015-12-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (4.004 Å)
主引用文献Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4X9I
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BU of 4x9i by Molmil
Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule, isoform 9.44, ...
著者Chen, Q, Yu, Y, Li, S.A, cheng, L.
登録日2014-12-11
公開日2015-12-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.904 Å)
主引用文献Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
4XB8
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BU of 4xb8 by Molmil
Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains (with zinc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule, ...
著者Chen, Q, Yu, Y, Li, S.A, cheng, L.
登録日2014-12-16
公開日2015-12-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
3ERD
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BU of 3erd by Molmil
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DIETHYLSTILBESTROL AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE
分子名称: ACETIC ACID, CHLORIDE ION, DIETHYLSTILBESTROL, ...
著者Shiau, A.K, Barstad, D, Loria, P.M, Cheng, L, Kushner, P.J, Agard, D.A, Greene, G.L.
登録日1999-03-31
公開日1999-04-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.
Cell(Cambridge,Mass.), 95, 1998
3ERT
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BU of 3ert by Molmil
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 4-HYDROXYTAMOXIFEN
分子名称: 4-HYDROXYTAMOXIFEN, PROTEIN (ESTROGEN RECEPTOR ALPHA)
著者Shiau, A.K, Barstad, D, Loria, P.M, Cheng, L, Kushner, P.J, Agard, D.A, Greene, G.L.
登録日1999-03-30
公開日1999-04-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.
Cell(Cambridge,Mass.), 95, 1998

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